ChemicalBook > CAS DataBase List > Cysteamine

Cysteamine

Product Name: Cysteamine
CAS No.: 60-23-1
Chemical Name: Cysteamine
Synonyms: CYSTEAMINE;mercaptamine;2-MERCAPTOETHYLAMINE;Cysteamin;Cysteamide;Cisteamina;2-amino-ethanethio;2-Amino-1-ethanethiol;β-MEA;L-1573
CBNumber: CB2223766
Molecular Formula: C2H7NS
Formula Weight: 77.15
MOL File: 60-23-1.mol

Less

Cysteamine Property

Melting point:: 95°C
Boiling point:: 130 °C
Density: 0.934 (estimate)
refractive index: 1.5300 (estimate)
storage temp.: 2-8°C
Water Solubility: Soluble in water
solubility: Water (soluble), Ethanol (soluble (95% EtOH))
pka: 8.35(at 25℃)
form: Powder
color: White to slightly yellow
Merck: 14,2779
BRN: 635649
Stability:: Stable, but may be air-sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference: 60-23-1(CAS DataBase Reference)
EPA Substance Registry System: Cysteamine (60-23-1)

Less

Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-36
RIDADR: 3259
WGK Germany: 3
RTECS: KJ0175000
F: 1-3-10-13-34
HS Code: 29309090
Hazardous Substances Data: 60-23-1(Hazardous Substances Data)
Toxicity: LD50 in mice (mg/kg): 625 orally; 250 i.p. (Klayman); (Srivastava, Field)

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 30070
Product name: Cysteamine
Purity: ≥98.0% (RT)
Packaging: 10g
Price: $200
Updated: 2025/07/31

Sigma-Aldrich

Product number: 641022
Product name: 2-Mercaptoethylamine, polymer-bound
Purity: 70-90?mesh, extent of labeling: 0.6-1.1?mmol/g loading, 1?% cross-linked with divinylbenzene
Packaging: 5G
Price: $316
Updated: 2025/07/31

Sigma-Aldrich

Product number: 30070
Product name: Cysteamine
Purity: ≥98.0% (RT)
Packaging: 50g
Price: $576.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: 641022
Product name: 2-Mercaptoethylamine, polymer-bound
Purity: 70-90?mesh, extent of labeling: 0.6-1.1?mmol/g loading, 1?% cross-linked with divinylbenzene
Packaging: 25G
Price: $1100
Updated: 2023/06/20

TCI Chemical

Product number: A0648
Product name: 2-Aminoethanethiol
Purity: >95.0%(T)
Packaging: 25g
Price: $55
Updated: 2025/07/31

Less

Cysteamine Chemical Properties,Usage,Production

Description

Cysteamine, also known as 2-aminoethanethiol, is a chemical compound with the formula HSCH₂CH₂NH₂. It is the simplest stable aminothiol and a degradation product of the amino acid cysteine. It is often used as the hydrochloride salt, HSCH2CH2NH3Cl. The comparatively high melting point of cysteamine (95-97 °C), indicates that exists in a salt form.

Chemical Properties

2-Aminoethanethiol is a white to pale yellow solid powder with a melting point of 99–100°C. It is readily soluble in water and alcohols, exhibits an alkaline reaction, and readily oxidises to form disulphides in air. The free base is highly unstable and is generally formulated as the hydrochloride salt [156-57-0].

Uses

2-Aminoethanethiol is used in preparation method of fluorescence quenching array sensor based on cadmium telluride quantum dots and application in qualitative discrimination and quantitative analysis of organic acids.

Application

Cysteamine is suitable for use:

in the preparation of cysteamine modified gold nanoparticles (AuNP)
in the fabrication of SU-8 microrods, where in, the amine group of cysteamine reacts with the unreacted epoxide rings present on the surface of the particles, thereby opening it and forming a covalent bond
to enhance in vitro development of porcine oocytes matured and fertilized in vitro
in a study to demonstrate the depletion effect of cysteamine on cystinotic leucocyte granular fractions of cystine by disulphide interchange
as a radioprotector
to administer subcutaneously in rats to study its blocking effect on somatostatin secretion without modifying the pancreatic insulin or glucagon content
as a scavenger in electrophoretic gels (acetic acid/urea gels)
Scavenges benzyl and allyl halides and ketones.

Definition

2-AMINOETHANETHIOL is an amine that consists of an ethane skeleton substituted with a thiol group at C-1 and an amino group at C-2. It is an antihyperlipidemic and HMG-CoA reductase inhibitor.

Preparation

Cysteamine can also be prepared by the reaction of ethylenimine with hydrogen sulfide.
(NHCH₂CH₂) + H₂S → HSCH₂CH₂NH₂.

Reactions

2-AMINOETHANETHIOL is used as the hydrochloride salt, as it readily oxidizes to the corresponding disulfide, in the presence of air. The amine portion of the molecule serves as a catalyst for this reaction.
4 HSCH₂CH₂NH₂ + O₂ → 2 NH₂CH₂CH₂SSCH₂CH₂NH₂ + 2 H₂O.

benefits

Cysteamine is a potent inhibitor of dopamine-β-hydroxylase, leading to dopamine accumulation. Within the hypothalamus, dopamine strongly promotes the synthesis and secretion of growth hormone (GH). The active ingredient contained within exerts physiological regulatory effects, including improving the body's nutrient absorption and conversion, accelerating the growth rate of livestock and poultry, reducing body fat deposition, inhibiting protein degradation, and promoting protein synthesis.

reaction suitability

reaction type: solution phase peptide synthesis
reagent type: catalyst
reagent type: chelator

Pharmaceutical Applications

Under the trade name Cystagon, cysteamine is used in the treatment of disorders of cystine excretion. Cysteamine cleaves the disulfide bond with cystine to produce molecules that can escape the metabolic defect in cystinosis and cystinuria.
It is also used for treatment of radiation sickness.
Cysteamine is used in the body to form the essential biochemical coenzyme A by combining with pantothenate and adenosine triphosphate.
In 2008, Raptor Pharmaceuticals started phase II clinical trials testing a delayed release (DR) preparation of cysteamine bitartrate for Huntington's disease. DR Cysteamine is also being investigated as a treatment for cystinosis, Batten disease, and non-alcoholic steatohepatitis.

Biochem/physiol Actions

Cysteamine (β-mercaptoethylamine) depletes cystine from patient′s cells and there by regulates renal glomerular function and increases growth in them. Therefore, cysteamine is considered to be a potential therapeutic for nephropathic cystinosis.

Safety Profile

Poison by intravenous, subcutaneous, and intraperitoneal routesModerately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of SO, and NOx,.

Purification Methods

It is soluble in H2O giving an alkaline reaction, and it has a disagreeable odour. A likely impurity is the disulfide cystamine which is not soluble in alkaline solution. Under a N2 atmosphere dissolve it in EtOH, evaporate to dryness and wash the white residue with dry pet ether, then sublime it at 0.1mm and store it under N2 at 0-10o in the dark. Its HgCl2 (2:3) complex has m 181-182o (from H2O), and its picrate has m 125-126o. [Mills & Bogert J Am Chem Soc 57 2328 1935, 62 1173 1940, Baddiley & Thain J Chem Soc 800 1952, Shirley Preparation of Organic Intermediates (J. Wiley) Vol 3 189 1951, Barkowski & Hedberg J Am Chem Soc 109 6989 1987, Beilstein 4 IV 1570.]

Cysteamine Preparation Products And Raw materials

Raw materials

Hydrogen Sulfide Ethyleneimine

Preparation Products

Thiacloprid 4-[[(2-aminoethyl)thio]methyl]-5-methylimidazole Fosthiazate Coenzyme A

Less

Cysteamine Suppliers

Americas 1 Austria 1 Canada 2 China 278 Europe 2 France 2 Germany 5 India 12 Japan 9 South Korea 1 Switzerland 3 The Netherlands 2 Ukraine 1 United Kingdom 10 United States 42 Global 371

Rhawn Reagent

Tel: 400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 1438
Advantage: 58

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 14948
Advantage: 58

Shanghai daoyang technology co., ltd

Tel: QQ:3150471267 13381681725
Email: 3150471267@qq.com
Country: China
ProdList: 464
Advantage: 58

Shanghai YanyiBao Pharmaceutical Technology Co., Ltd.

Tel: 13661744693
Email: wangyue@yybyy.com
Country: China
ProdList: 598
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2208
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768836
Email: 1791901229@qq.com
Country: China
ProdList: 6950
Advantage: 52

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

ZhengZhou HuaWen Chemical Co.Ltd

Tel: 0370-2785118 17550508557
Fax: QQ：3470079902
Email: 675141927@qq.com
Country: China
ProdList: 3199
Advantage: 55

Beijing Taiya Jie Technology Development Co., Ltd.

Tel: 021-33690831-8001 13552411790
Fax: 021-33690831
Email: postmaster@tyjchem.cn
Country: China
ProdList: 1542
Advantage: 55

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9658
Advantage: 60

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4747
Advantage: 58

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4999
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Nanjing Dulai Biotechnology Co., Ltd.

Tel: 025-846993838003-8003 18013301590
Fax: 025-84699383-8003
Email: njduly@126.com
Country: China
ProdList: 3249
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Wuhan DKY Technology Co.,Ltd.

Tel: 027-27-81302488 15972195220
Fax: 027-81302088
Email: info@dkybpc.com
Country: China
ProdList: 1758
Advantage: 58

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Huainan Kedi Chemical Factory

Tel: 0554-2106669
Fax: 0554-2666215
Email: sales1@kedichem.com
Country: China
ProdList: 4924
Advantage: 55

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Shanghai CanSpecsci Instrument Co., Ltd.

Tel: 400-6087598 15021221957
Fax: 4006087598-8012
Email: order@canspecsci.com
Country: China
ProdList: 2001
Advantage: 56

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Chizhou Kailong Import and Export Trade Co., Ltd.

Tel
Fax: -
Email: xg01_gj@163.com
Country: China
ProdList: 9484
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Giant chemicals

Tel: 028-85434334 18108076537
Fax: QQ：245797092
Email: market@gianthx.com
Country: China
ProdList: 4505
Advantage: 56

Beijing NuoqiYa Biotechnology Co., Ltd.

Tel: 4000-819-385 010-62329685 13718666987
Fax: 010-62340519
Country: China
ProdList: 1971
Advantage: 55

Chengdu Research Accelerators Technology Co., Ltd.

Tel: 028-64353063
Fax: 028-64353063 QQ:784253935
Email: reacchemical@163.com
Country: China
ProdList: 5253
Advantage: 58

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9951
Advantage: 56

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Less

View Lastest Price from Cysteamine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Cysteamine 60-23-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-15

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Cysteamine Powder 60-23-1
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-15

Shaanxi Dideu Medichem Co. Ltd

Product: 2-AMINOETHANETHIOL 60-23-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-25

60-23-1, CysteamineRelated Search:

LANTHIONINE Z-CYS(BZL)-OH N-Acetyl-L-cysteine D-PENICILLAMINE DISULFIDE CHES N-ACETYL-DL-PENICILLAMINE S-CARBOXYMETHYL-L-CYSTEINE Pseudothiohydantoin Tiopronin D-Cystine S-Methyl-L-cysteine 2-(BUTYLAMINO)ETHANETHIOL S-tert-Butylmercapto-l-cysteine Taurodeoxycholic acid sodium salt DL-Cysteine S-Trityl-L-cysteine DL-PENICILLAMINE 2-Aminoethanethiol·hydrochloric acid,2-Aminoethanethiol hydrochloride ( cysteamine hydrochloride)

2-Amino-1-ethanethiol

2-amino-ethanethio

2-Aminoethyl mercaptan

2-aminoethylmercaptan

THIOETHANOLAMINE

2-MERCAPTOETHYLAMINE

2-MERCAPTOETHYLAMINE, POLYMER-BOUND

2-AMINOETHANETHIOL

DECARBOXYCYSTEINE

CYSTEAMINE

AURORA KA-7615

Beeaptan

BETA-MERCAPTOETHYLAMINE

cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine, Mercaptamine

2-mercaptoethylammonium

2-Aminoet-hylmercaptan

2-Mercaptoethanamine

Ethanethiol, 2-aMino-(8CI,9CI)

CysteaMine ~95%

Cysteamine(β-MEA)

Aminoethyl mercaptan

Becaptan

beta-Aminoethanethiol

beta-Aminoethylthiol

beta-MEA

Cisteamina

Cysteamide

Cysteamin

Cysteinamine

Ethanethiol, 2-amino-

Ethanethiolamine

L-1573

Lambraten

Lambratene

Mecramine

Mercamin

Mercamine

Mercaptamin

mercaptamine

2-AMINOETHANETHIOL 156-57-0

-Mercaptoethylamine

Merkamin

Riacon

2-Aminoethanthiol

2-mercaptoethylamine free base

2,2,4-trimethyl-1,2-dihydroquinoline (oligomers)

C01678

Cysteamine,β-Mercaptoethylamine, 2-Aminoethanethiol, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine

Cysteamine 2-Mercaptoethylamine

CYSTEAMINE HYDROCHLORIDE(P)

β-Mercaptoethylamine, 2-Aminoethanethiol, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine

JACS-60-23-1

2-Aminoethanethiol &gt

Aminoethanethiol...

cysteanine

2-AMINOETHANETHIOL USP/EP/BP

β-MEA

β-Mercaptoethylamine