N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE

Product Name: N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE
CAS No.: 5462-30-6
Chemical Name: N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE
Synonyms: 4,5-DICHLORO-2-NITROACETANILIDE;Dichloro-2-nitro-acetanilide,4,5-;4',5'-Dichloro-2'-nitroacetanilide;4,5-DICHLORO-2-NITRO-N-ACETYLANILINE;N-(4,5-dichloro-2-nitrophenyl)acetamid;N-(4,5-dichloro-2-aminophenyl)Acetamide;N-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE;N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE;4,5 DI CHLORO 2-NITRO ACETANILIDE 98%HPLC;ACETAMIDE, N-(4,5-DICHLORO-2-NITROPHENYL)-
CBNumber: CB2251039
Molecular Formula: C8H6Cl2N2O3
Formula Weight: 249.05
MOL File: 5462-30-6.mol

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N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE Property

Melting point:: 124-128 °C(lit.)
Boiling point:: 418.4±45.0 °C(Predicted)
Density: 1.573±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
pka: 12.29±0.70(Predicted)
color: White to Light yellow
InChI: InChI=1S/C8H6Cl2N2O3/c1-4(13)11-7-2-5(9)6(10)3-8(7)12(14)15/h2-3H,1H3,(H,11,13)
InChIKey: ZEGRPTYRAGSSBH-UHFFFAOYSA-N
SMILES: C(NC1=CC(Cl)=C(Cl)C=C1[N+]([O-])=O)(=O)C
CAS DataBase Reference: 5462-30-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-36/37
WGK Germany: 3
HS Code: 2924190090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 641715
Product name: N-(4,5-Dichloro-2-nitrophenyl)acetamide
Purity: 97%
Packaging: 5g
Price: $90
Updated: 2023/01/07

TCI Chemical

Product number: D4907
Product name: 4',5'-Dichloro-2'-nitroacetanilide
Purity: >97.0%(GC)
Packaging: 5g
Price: $119
Updated: 2025/07/31

TCI Chemical

Product number: D4907
Product name: 4',5'-Dichloro-2'-nitroacetanilide
Purity: >97.0%(GC)
Packaging: 25g
Price: $371
Updated: 2025/07/31

TRC

Product number: D436673
Product name: N-(4,5-Dichloro-2-nitrophenyl)acetamide
Packaging: 500mg
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: J91699
Product name: N1-(4,5-Dichloro-2-nitrophenyl)acetamide
Packaging: 1g
Price: $12
Updated: 2021/12/16

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N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE Chemical Properties,Usage,Production

Synthesis

2150-93-8

5462-30-6

The general procedure for the synthesis of N1-(4,5-dichloro-2-nitrophenyl)acetamide from N-(3,4-dichlorophenyl)acetamide was as follows: 3,4-dichloroacetanilide (II) (150 g, 0.74 mol) was slowly added to a reactor containing sulfuric acid (270 g, 99%, 2.7 mol) at 13 °C, stirred for 0.5 h and then cooled to 8 °C. Subsequently, fuming sulfuric acid (422 g, 31.1%, 4.61 mol) was slowly added to obtain a mixture. The sulfuric acid concentration of this mixture was 104%, where the molar ratio of 3,4-dichloroacetanilide (II) to sulfuric acid was 1:10. The mixture was further cooled to 3 °C and nitric acid (51 g, 98%, 0.79 mol) was slowly added over a period of 5 hours. The progress of the reaction was monitored by thin layer chromatography (TLC).3,4-Dichloroacetanilide was completely consumed within 1 h to give the product mixture. The product mixture was carefully poured into a mixture of 1650 g of ice with 200 ml of water, maintained at a temperature below 15 °C and stirred for 15 min to form a dispersion. The dispersion was filtered to give a residue containing 2-nitro-4,5-dichloroacetanilide (I). The residue was washed with water until no residual acid remained and dried to give 2-nitro-4,5-dichloroacetanilide (I) (174 g, yield = 95.23%, HPLC purity = 97.83%).HPLC analysis showed that the product contained 1.46% III.

References

[1] Patent: WO2018/91978, 2018, A1. Location in patent: Page/Page column 7-8
[2] Journal of Medicinal Chemistry, 1995, vol. 38, # 10, p. 1786 - 1792

N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE Suppliers

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View Lastest Price from N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd

Product: N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE 5462-30-6
Price: US $95.00-950.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-09

Career Henan Chemical Co

Product: N1-(4,5-Dichloro-2-Nitrophenyl)Acetamide 5462-30-6
Price: US $8.00/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: kg--ton
Release date: 2020-03-08

5462-30-6, N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDERelated Search:

2'-NITROACETANILIDE 5-CHLORO-N-METHYL-2-NITROBENZENAMINE 3,4-Dichloronitrobenzene N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE 4-Chloro-o-phenylenediamine N-ETHYL-2-NITROANILINE 2'-AMINOACETANILIDE 4-Chloro-2-nitroaniline 5-Chloro-2-nitroaniline 4'-CHLOROACETANILIDE N-Acetyl-N-(4-chloro-2-nitrophenyl)acetamide N-Methyl-1,2-benzenediamine dihydrochloride N-ETHYL 4-CHLORO-2-NITROANILINE 4,5-Dichloro-1,2-benzenediamine OPD EASY-tablets 3,4-DICHLOROACETANILIDE 2-NITROANILINE HYDROCHLORIDE (3,4-DICHLORO-PHENYL)-ETHYL-AMINE

N-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE

N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE

4,5-DICHLORO-2-NITROACETANILIDE

4,5-DICHLORO-2-NITRO-N-ACETYLANILINE

ACETAMIDE, N-(4,5-DICHLORO-2-NITROPHENYL)-

N-(4,5-dichloro-2-aminophenyl)Acetamide

Dichloro-2-nitro-acetanilide,4,5-

4,5 DICHLORO 2-NITRO ACETANILIDE 99.0 % G.C.

4,5 DI CHLORO 2-NITRO ACETANILIDE 98%HPLC

N-(4,5-dichloro-2-nitrophenyl)acetamid

2-(4-chlorophenoxy)-2-sulfanylidene-1,3-dihydro-1,3,2$l^{5}-benzodiazaphosphole

4,5 Dichloro 2 Nitro Acetanilide (Stage III)

4',5'-Dichloro-2'-nitroacetanilide

<i>N</i>-(4,5-Dichloro-2-nitrophenyl)acetamide

5462-30-6

C8H6Cl2N2O3

Building Blocks

Amides

Carbonyl Compounds

Organic Building Blocks

Amides

Building Blocks

Carbonyl Compounds

Chemical Synthesis

Organic Building Blocks

Anilines, Amides & Amines

Chlorine Compounds

Nitro Compounds