BOC-SAR-OH

Product Name: BOC-SAR-OH
CAS No.: 13734-36-6
Chemical Name: BOC-SAR-OH
Synonyms: BOC-SAR;BOC-SARCOSINE;2-((tert-butoxycarbonyl)(Methyl)aMino)acetic acid;BOC-SAR-OH;BOC-MEGLY-OH;Boc-L-Sar-OH;BOC-N-ME-GLY-OH;N-BOC-SARCOSINE;N-T-BOC-SARCOSIN;N-t-Boc-sarcosine
CBNumber: CB2253437
Molecular Formula: C8H15NO4
Formula Weight: 189.21
MOL File: 13734-36-6.mol

More

Less

BOC-SAR-OH Property

Melting point:: 88-90 °C
Boiling point:: 324.46°C (rough estimate)
Density: 1.2321 (rough estimate)
refractive index: 1.4540 (estimate)
storage temp.: 2-8°C
solubility: Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
form: Crystals or Crystalline Powder
pka: 4.03±0.10(Predicted)
color: White
BRN: 2046827
Stability:: Hygroscopic
InChI: InChI=1S/C8H15NO4/c1-8(2,3)13-7(12)9(4)5-6(10)11/h5H2,1-4H3,(H,10,11)
InChIKey: YRXIMPFOTQVOHG-UHFFFAOYSA-N
SMILES: C(O)(=O)CN(C(OC(C)(C)C)=O)C
CAS DataBase Reference: 13734-36-6(CAS DataBase Reference)
EPA Substance Registry System: Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl- (13734-36-6)

More

Less

Safety

Safety Statements: 24/25
WGK Germany: 3
F: 21
TSCA: Yes
HazardClass: IRRITANT
HS Code: 29241990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.53062
Product name: Boc-Sar-OH
Purity: Novabiochem?
Packaging: 5G
Price: $24.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.53062
Product name: Boc-Sar-OH
Purity: Novabiochem?
Packaging: 25g
Price: $55.9
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.53062
Product name: Boc-Sar-OH
Purity: Novabiochem?
Packaging: 100g
Price: $155
Updated: 2025/07/31

Sigma-Aldrich

Product number: 15495
Product name: Boc-Sar-OH
Purity: ≥99.0% (T)
Packaging: 5g
Price: $37.1
Updated: 2023/06/20

Sigma-Aldrich

Product number: 15495
Product name: Boc-Sar-OH
Purity: ≥99.0% (T)
Packaging: 25g
Price: $97.5
Updated: 2023/06/20

More

Less

BOC-SAR-OH Chemical Properties,Usage,Production

Chemical Properties

white crystals or crystalline powder

Uses

Boc-N-methylglycine is used in the preparation of Clavatustide A (C563723) and Clavatustide B (C563725), which have been shown to suppress the proliferation of human hepatocellular carcinoma cells under specific conditions.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

107-97-1

24424-99-5

13734-36-6

Triethylamine (23.5 mL, 168.3 mmol) and di-tert-butyl dicarbonate (12.9 mL, 56.1 mmol) were sequentially added to an aqueous (375 mL) solution of sarcosine (5.0 g, 56.1 mmol), and the reaction mixture was stirred for 6 hours at room temperature. After completion of the reaction, hydrochloric acid solution (320 mL, 1 M aqueous solution) and ethyl acetate were added for acidification and extraction. After separation of the aqueous layer, the aqueous layer was further extracted with ethyl acetate. The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give a colorless oil. The oily substance was crystallized at -15 °C to afford the target product 2-((tert-butoxycarbonyl)(methyl)amino)acetic acid (10.6 g, quantitative yield) as a white solid and a mixture of rotary isomers was observed.

References

[1] Tetrahedron Letters, 2017, vol. 58, # 7, p. 602 - 605
[2] Journal of the American Chemical Society, 2003, vol. 125, # 35, p. 10664 - 10671
[3] Synthesis, 1996, # 10, p. 1246 - 1258
[4] Patent: WO2005/39506, 2005, A2. Location in patent: Page/Page column 93-94
[5] Patent: WO2005/39506, 2005, A2. Location in patent: Page/Page column 93-94

BOC-SAR-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BOC-SAR-OH Suppliers

Belgium 1 China 261 France 1 Germany 6 India 6 Japan 5 South Korea 1 Switzerland 2 Ukraine 1 United Kingdom 9 United States 39 Global 332

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
Fax: +1 (561) 791-8728
Email: service@chempep.com
Country: United States
ProdList: 2138
Advantage: 57

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10648
Advantage: 60

AbaChemScene

Tel: 732-484-9848
Fax: 888-484-5008
Email: sales@chemscene.com
Country: United States
ProdList: 3982
Advantage: 60

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

AB PharmaTech,LLC

Tel: 323-480-4688
Fax: 323-480-4688
Email: sales@acrospharmatech.com
Country: United States
ProdList: 989
Advantage: 55

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Alfa Chemistry

Tel: --
Fax: --
Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

Peptides International, Inc.

Tel: --
Fax: --
Email: peptides@pepnet.com
Country: United States
ProdList: 555
Advantage: 72

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Pure Chemistry Scientific Inc

Tel: --
Fax: --
Email: sales@purechems.com
Country: United States
ProdList: 2321
Advantage: 50

Cambridge Isotope Laboratories, Inc.

Tel: --
Fax: --
Email: cilsales@isotope.com
Country: United States
ProdList: 6598
Advantage: 79

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6962
Advantage: 56

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

AlliChem, LLC

Tel: --
Fax: --
Email: sales@allichemllc.com
Country: United States
ProdList: 6516
Advantage: 60

Chem-Impex International, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6730
Advantage: 64

Advanced Synthesis Technologies

Tel: --
Fax: --
Email: sales@advancedsynthesis.com
Country: United States
ProdList: 4775
Advantage: 61

Beta Pharma, Inc.

Tel: --
Fax: --
Email: sales@betapharma.com
Country: United States
ProdList: 6226
Advantage: 60

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: United States
ProdList: 6814
Advantage: 81

INDOFINE Chemical Company, Inc.

Tel: --
Fax: --
Email: chemical@indofinechemical.com
Country: United States
ProdList: 6176
Advantage: 69

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

APAC Pharmaceutical, LLC

Tel: --
Fax: --
Email: sales@apacpharma.com
Country: United States
ProdList: 6322
Advantage: 38

Sciencelab.com, Inc.

Tel: --
Fax: --
Email: accounting@sciencelab.com
Country: United States
ProdList: 4159
Advantage: 82

Advance Scientific & Chemical

Tel: --
Fax: --
Email: sales@advance-scientific.com
Country: United States
ProdList: 6419
Advantage: 71

Ivy Fine Chemicals

Tel: --
Fax: --
Email: sales@ivychem.com
Country: United States
ProdList: 6493
Advantage: 58

BOSCHE SCIENTIFIC, LLC

Tel: --
Fax: --
Email: Sales@BoscheSci.com
Country: United States
ProdList: 6477
Advantage: 55

EMD Biosciences, Inc.

Tel: --
Fax: --
Email: technical@calbiochem.com
Country: United States
ProdList: 6529
Advantage: 66

Spectrum Chemicals & Laboratory Products

Tel: --
Fax: --
Email: sales@spectrumchemical.com
Country: United States
ProdList: 6699
Advantage: 77

AnaSpec, Inc.

Tel: --
Fax: --
Email: service@anaspec.com
Country: United States
ProdList: 4871
Advantage: 77

Advanced ChemTech

Tel: --
Fax: --
Country: United States
ProdList: 1606
Advantage: 69

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

Chontech, Inc.

Tel: --
Fax: --
Email: chontech@yahoo.com
Country: United States
ProdList: 1101
Advantage: 30

More

Less

View Lastest Price from BOC-SAR-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-Sar-OH 13734-36-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T
Release date: 2023-11-14

Anhuyan (Hainan) Biotechnology Co., LTD

Product: BOC-SAR-OH 13734-36-6
Price: US $0.00/G/KG
Min. Order: 1G/KG
Purity: 99%
Supply Ability: 10000000KG
Release date: 2025-02-12

Hebei Chuanghai Biotechnology Co,.LTD

Product: N-Boc-Sarcosine 13734-36-6
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-13

13734-36-6, BOC-SAR-OHRelated Search:

BOC-ORN-OH Boc-N-beta-Trityl-L-asparagine N-tert-Butoxycarbonyl-L-glutamic acid gamma-tert-butyl ester Boc-L-aspartic acid 4-tert-butyl ester Boc-6-AMinocaproic acid BOC-NLE-OH DCHA Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate Boc-L-glutamic acid 5-cyclohexyl ester Boc-D-aspartic acid 4-benzyl ester BOC-GLU(OFM)-OH BOC-PHE-SER-ARG-AMC ACETATE SALT BOC-4-IODO-L-PHENYLALANINE Boc-N-methyl-L-leucine BOC-D-MEPHE-OH DCHA N-tert-Butyloxycarbonyl-N-methyl-O-benzyl-L-threonine BOC-N-Methyl-L-alanine BOC-HYP(BZL)-OH Sarcosine

BOC-SARCOSINE

BOC-SAR

BOC-SAR-OH

Boc-N-methylglycine, Boc-sarcosine

2-[methyl-[(2-methylpropan-2-yl)oxy-oxomethyl]amino]acetate

N-[(1,1-dimethylethoxy)carbonyl]sarcosine

Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-

Glycine, N-methyl-N-(t-butoxycarbonyl)-

n-[(1,1-dimethylethoxy)carbonyl]-n-methyl-glycin

N-[(1,1-Dimethylethoxy)carbonyl]-N-methylglycine

N-t-Boc-sarcosine

BOC-Sarcosine, 99+%

N-T-BUTYLOXYCARBONYL-SARCOSINE, N-T-BUTYLOXYCARBONYL-N-METHYL-GLYCINE

(Tert-Butoxy)Carbonyl Sar-OH

N-tert-Butoxycarbonyl-N-methylglycine

N-Boc-Sarcosine (Boc-Sar-OH) ,99% (GC)

[(tert-Butoxycarbonyl)(methyl)amino]acetic acid, Sarcosine, N-BOC proteced

N-Methylglycine, N-BOC protected

Boc-N-methylglycine≥ 98% (HPLC)

BOC-N-ME-GLY-OH

BOC-N-METHYLGLYCINE

BOC-N-ALPHA-METHYLGLYCINE

BOC-MEGLY-OH

RARECHEM EM WB 0206

T-BUTYLOXYCARBONYLSARCOSINE

N-(TERT-BUTOXYCARBONYL)SARCOSINE

N-TERT-BUTYLOXYCARBONYL-SARCOSINE

N-TERT-BUTYLOXYCARBONYL-N-METHYL-GLYCINE

N-T-BUTOXYCARBONYL SARCOSINE

N-T-BOC-SARCOSIN

N-BOC-SARCOSINE

N-BOC-N-METHYLGLYCINE

N-ALPHA-T-BUTOXYCARBONYL-N-ALPHA-METHYL-GLYCINE

N-ALPHA-T-BUTOXYCARBONYL SARCOSINE

N-ALPHA-T-BOC-N-ALPHA-METHYLGLYCINE

N-ALPHA-T-BOC-SARCOSINE

[(tert-Butoxycarbonyl)(methyl)amino]acetic acid

Boc-Sar-OH >=99.0% (T)

Boc-L-Sar-OH

BOC-SAR-OH;BOC-N-METHYLGLYCINE

2-((tert-butoxycarbonyl)(Methyl)aMino)acetic acid

BOC-SAR-OH USP/EP/BP

Tert butoxycarbonyl-l-sarcosine

2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetic acid

Isavuconazole Impurity 70

Tert-butoxycarbonyl sarcosine

BOC(Methyl)amino]acetic acid

13734-36-6

734-36-6

CH33COCONCH3CH2COOH

Amino Acid Derivatives

Specialty Synthesis

Peptide Synthesis

Amino Acids

Sarcosine [Sar]

Unusual Amino Acids