1-N-Boc-4-(Phenylamino)piperidine Property

Melting point:

136-137

Boiling point:

400.6±38.0 °C(Predicted)

Density 

1.107±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

DMF: 15mg/mL; DMSO: 25mg/mL; Ethanol: 25mg/mL; Ethanol:PBS (pH 7.2) (1:1): 0.5mg/mL

form 

A crystalline solid

pka

5.00±0.20(Predicted)

InChI

InChI=1S/C16H24N2O2/c1-16(2,3)20-15(19)18-11-9-14(10-12-18)17-13-7-5-4-6-8-13/h4-8,14,17H,9-12H2,1-3H3

InChIKey

HTIWISWAPVQGMI-UHFFFAOYSA-N

SMILES

N1(C(OC(C)(C)C)=O)CCC(NC2=CC=CC=C2)CC1

Safety

Hazard Codes 

Xi,Xn

Risk Statements 

22

Hazard Note 

Harmful/Irritant

HazardClass 

IRRITANT

HS Code 

2933399990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

1-N-Boc-4-(Phenylamino)piperidine Chemical Properties,Usage,Production

Description

4-Anilino-1-Boc-piperidine is an analytical reference standard that is structurally similar to known opioids. 4-Anilino-1-Boc-piperidine is a precursor in the synthesis of 4-anilinopiperidine . This product is intended for research and forensic applications.

Chemical Properties

Pale Brown Solid

Uses

Intermediate in the preparation of Fentanyl derivatives.

Application

1-N-Boc-4-(Phenylamino)piperidine is an amino acid derivative widely employed as a reagent in organic synthesis. This compound exhibits remarkable versatility, finding applications in various fields such as peptide and protein synthesis, organic synthesis, and drug development. It possesses strong basic properties, allowing for diverse reactions with acids that lead to the formation of a wide array of products. The extensive use of this compound in organic synthesis is well-documented, particularly in the synthesis of peptides and proteins. By facilitating the coupling of amino acids, it enables the creation of peptides that can be utilized in diverse applications, including the development of pharmaceutical drugs.