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3-(Aminomethyl)pyridine

Product Name
3-(Aminomethyl)pyridine
CAS No.
3731-52-0
Chemical Name
3-(Aminomethyl)pyridine
Synonyms
pyridin-3-ylmethanamine;Picolamine;3AMPY;NSC 59706;Picolamin;-Aminomethyl;3-PICOLYLAMINE;AKOS BBS-00003679;3-Picolylamine>TIMTEC-BB SBB004351
CBNumber
CB2284635
Molecular Formula
C6H8N2
Formula Weight
108.14
MOL File
3731-52-0.mol
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3-(Aminomethyl)pyridine Property

Melting point:
−21 °C(lit.)
Boiling point:
73-74 °C1 mm Hg(lit.)
Density 
1.062 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.551(lit.)
Flash point:
213 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Chloroform, Ethyl Acetate, Methanol
pka
8.34±0.29(Predicted)
form 
clear liquid
color 
Colorless to Light yellow
PH
11-12 (100g/l, H2O, 20℃)
Water Solubility 
FREELY SOLUBLE
Sensitive 
Air Sensitive
BRN 
108056
CAS DataBase Reference
3731-52-0(CAS DataBase Reference)
NIST Chemistry Reference
Picolamine(3731-52-0)
EPA Substance Registry System
3-Pyridinemethanamine (3731-52-0)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
34-37-36/37/38
Safety Statements 
26-36/37/39-45-25-36
RIDADR 
UN 2735 8/PG 2
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

Precautionary statements

P234Keep only in original container.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A65409
Product name
3-Picolylamine
Purity
≥99%
Packaging
5g
Price
$31.1
Updated
2024/03/01
Sigma-Aldrich
Product number
A65409
Product name
3-Picolylamine
Purity
≥99%
Packaging
100g
Price
$76
Updated
2024/03/01
TCI Chemical
Product number
P0762
Product name
3-Picolylamine
Purity
>99.0%(GC)
Packaging
25mL
Price
$19
Updated
2024/03/01
TCI Chemical
Product number
P0762
Product name
3-Picolylamine
Purity
>99.0%(GC)
Packaging
100mL
Price
$50
Updated
2024/03/01
Alfa Aesar
Product number
B23634
Product name
3-(Aminomethyl)pyridine, 98+%
Packaging
25g
Price
$45.2
Updated
2024/03/01
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3-(Aminomethyl)pyridine Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS TO SLIGHLY YELLOW LIQUID

Uses

It finds its application as a rubefacient.

Application

3-(Aminomethyl)pyridine can be used to prepare metal complexes. A number of complexes of cobalt(II), nickel(II) and copper(II) thiocyanates, chlorides and bromides with 3-pyridine amine were prepared and the stereochemical configurations of these complexes were deduced using spectroscopy and magnetism, and the decomposition of the complexes was studied by thermogravimetry and differential thermal analysis[2].

Synthesis

Synthesis of 3-(aminomethyl)pyridine by traceless C3-selective umpolung of 1-amidopyridin-1-ium salts?. A natural product inspired rapid access of 3-(aminomethyl)pyridine by one-pot reaction of 1-amidopyridin-1-ium salt with aminal followed by reductive cleavage of the N–N bond is developed. This C3-selective formal C–H activation of pyridine features a traceless umpolung of the 1-amidopyridin-1-ium salt toward a Mannich type C–C bond formation of the in situ generated 1-amido-2-dialkylamino-1,2-dihydropyridine intermediate[1].

References

[1] TANG P, XIAO D, WANG B. Synthesis of 3-(aminomethyl)pyridine by traceless C3-selective umpolung of 1-amidopyridin-1-ium salts?[J]. Chemical Communications, 2017. DOI:10.1039/C6CC09582H.
[2] J. R. ALLAN  M. J P  A D Paton. The preparation, characterisation and thermal analysis studies on complexes of cobalt(II), nickel(II), and copper(II) with 3-picolylamine[J]. Journal of Thermal Analysis and Calorimetry, 1985. DOI:10.1007/BF01913603.

3-(Aminomethyl)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-(Aminomethyl)pyridine manufacturers

Henan Fengda Chemical Co., Ltd
Product
Picolamine 3731-52-0
Price
US $122.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
3-(Aminomethyl)pyridine 3731-52-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
3-(Aminomethyl)pyridine 3731-52-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

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