1-(2-Methoxyethyl)piperazine

Product Name: 1-(2-Methoxyethyl)piperazine
CAS No.: 13484-40-7
Chemical Name: 1-(2-Methoxyethyl)piperazine
Synonyms: gx1011-aM;RARECHEM AH CK 0124;Methoxyethylpiperazine;1-(2-METHOXYETHYL)PIPERAZINE;N-(2-Methoxyethyl)piperazine;4-(2-Methoxyethyl)piperazine;1-N- Methoxyethyl piperazine;1-(2-Methoxyethyl)piperzazine;1-(2-Methoxyethyl)piperazine>Piperazine, 1-(2-methoxyethyl)-
CBNumber: CB2315317
Molecular Formula: C7H16N2O
Formula Weight: 144.21
MOL File: 13484-40-7.mol

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1-(2-Methoxyethyl)piperazine Property

Melting point:: 100-101 °C
Boiling point:: 193-194 °C (lit.)
Density: 0.970 g/mL at 25 °C (lit.)
refractive index: n20/D 1.4730(lit.)
Flash point:: 188 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 9.15±0.10(Predicted)
form: Liquid
color: Clear colorless to yellow
BRN: 105098
InChIKey: BMEMBBFDTYHTLH-UHFFFAOYSA-N
CAS DataBase Reference: 13484-40-7(CAS DataBase Reference)

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Safety

Hazard Codes: C,Xi
Risk Statements: 34-36/37/38
Safety Statements: 26-36/37/39-45-37/39
RIDADR: UN 2735 8/PG 3
WGK Germany: 3
F: 10-34
Hazard Note: Irritant
HazardClass: 8
PackingGroup: Ⅲ
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H227Combustible liquid

H314Causes severe skin burns and eye damage

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 571423
Product name: 1-(2-Methoxyethyl)piperazine
Purity: 97%
Packaging: 1g
Price: $42.3
Updated: 2023/01/07

TCI Chemical

Product number: M2169
Product name: 1-(2-Methoxyethyl)piperazine
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $81
Updated: 2025/07/31

TCI Chemical

Product number: M2169
Product name: 1-(2-Methoxyethyl)piperazine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $205
Updated: 2025/07/31

TRC

Product number: M304298
Product name: 1-(2-Methoxyethyl)piperazine
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M304298
Product name: 1-(2-Methoxyethyl)piperazine
Packaging: 1g
Price: $75
Updated: 2021/12/16

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1-(2-Methoxyethyl)piperazine Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to yellow liquid

Uses

Reactant for:• ;Preparation of biologically and pharmacologically active molecules1,2,3,4,5

Uses

Reactant for:

Preparation of biologically and pharmacologically active molecules

Synthesis

110-85-0

627-42-9

13484-40-7

13484-41-8

Under nitrogen protection, 8.6 g (0.1 mol) of piperazine and 10.4 g of methanol were added to the reaction flask, 35 µl of hydrochloric acid (10.4 g, 0.1 mol) was added with stirring, and the internal temperature was controlled to 80 °C. Under the condition of keeping the internal temperature below 80 °C, 8.7 g (0.07 mol) of 2-bromoethanol was added slowly and dropwise over 0.5 h. Subsequently, the reaction was continued with stirring at the same temperature for 8 h. 36.9 g of colorless and transparent reaction solution was obtained. Gas chromatographic analysis showed a yield of 84.6% for N-(2-hydroxyethyl)piperazine, with a selectivity of 88.5% for N-(2-hydroxyethyl)piperazine, 7.7% for N,N'-bis(2-hydroxyethyl)piperazine, and 3.8% for the unknown component. Compared to the results of Example 2 in Table 1 , the reaction conditions were the same as in Example 2 when 3.8 g (0.04 mol) of 2-methoxyethyl ester was used in place of 2-bromoethanol. GC analysis showed a 70.1% yield of N-(2-methoxyethyl)piperazine with a selectivity of 83.4% for N-(2-methoxyethyl)piperazine, 15.0% for N,N'-bis(2-methoxyethyl)piperazine, and 1.6% for the unknown component. This result is consistent with the results of Example 5 in Table 1.

References

[1] Patent: JP5838628, 2016, B2. Location in patent: Paragraph 0056; 0059

1-(2-Methoxyethyl)piperazine Preparation Products And Raw materials

Raw materials

1-Bromo-2-methoxyethane Ethanol Sodium sulfate Triethylamine Piperazine Hydrochloric acid Sodium bicarbonate Dichloromethane Sodium hydroxide 1-BOC-Piperazine 2-Methoxyethyl chloride

Preparation Products

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1-(2-Methoxyethyl)piperazine Suppliers

Americas 1 Belgium 3 CHINA 135 Europe 1 France 1 Germany 9 India 8 Japan 2 Russia 1 South Korea 1 Switzerland 3 The Netherlands 1 Ukraine 2 United Kingdom 9 United States 34 Global 211

J & K SCIENTIFIC LTD.

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Alfa Aesar

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Energy Chemical

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

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View Lastest Price from 1-(2-Methoxyethyl)piperazine manufacturers

Firsky International Trade (Wuhan) Co., Ltd

Product: 1-(2-Methoxyethyl)piperazine 13484-40-7
Price: US $30.00/L
Min. Order: 1L
Purity: 99%
Supply Ability: 20T
Release date: 2023-10-08

Honest Joy Holdings Limited

Product: 1-(2-Methoxyethyl)piperazine 13484-40-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.4%
Supply Ability: 100 tons
Release date: 2022-01-25

Career Henan Chemical Co

Product: 1-(2-Methoxyethyl)piperazine 13484-40-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-07-02

13484-40-7, 1-(2-Methoxyethyl)piperazineRelated Search:

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RARECHEM AH CK 0124

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13484-40-7

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