Uses
ChemicalBook > CAS DataBase List > 1,1-Cyclobutanedicarboxylic acid

1,1-Cyclobutanedicarboxylic acid

Uses
Product Name
1,1-Cyclobutanedicarboxylic acid
CAS No.
5445-51-2
Chemical Name
1,1-Cyclobutanedicarboxylic acid
Synonyms
CYCLOBUTANE-1,1-DICARBOXYLIC ACID;1-Cyclobutanedicarboxylic acid;H2cbdca;226-651-2;1,1-Cyclobutanedicar;Carboplatin Impurity 1;Carboplatin impurity B;obutane-1,1-dicarboxyL;1,1-Dicarboxycyclobutane;Carboplatin EP Impurity B
CBNumber
CB2315559
Molecular Formula
C6H8O4
Formula Weight
144.13
MOL File
5445-51-2.mol
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1,1-Cyclobutanedicarboxylic acid Property

Melting point:
158 °C(lit.)
Boiling point:
222.71°C (rough estimate)
Density 
1.3217 (rough estimate)
refractive index 
1.5800 (estimate)
storage temp. 
Store below +30°C.
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
pK1:3.13 ;pK2:5.88 (25°C)
form 
Fine Crystalline Powder
color 
White
BRN 
2046031
InChI
InChI=1S/C6H8O4/c7-4(8)6(5(9)10)2-1-3-6/h1-3H2,(H,7,8)(H,9,10)
InChIKey
CCQPAEQGAVNNIA-UHFFFAOYSA-N
SMILES
C1(C(O)=O)(C(O)=O)CCC1
CAS DataBase Reference
5445-51-2(CAS DataBase Reference)
NIST Chemistry Reference
1,1-Cyclobutanedicarboxylic acid(5445-51-2)
EPA Substance Registry System
1,1-Cyclobutanedicarboxylic acid (5445-51-2)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45-28A
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
Hazard Note 
Corrosive
TSCA 
T
HazardClass 
8
PackingGroup 
III
HS Code 
29172000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C95803
Product name
Cyclobutane-1,1-dicarboxylic acid
Purity
99%
Packaging
5g
Price
$55.4
Updated
2024/03/01
TCI Chemical
Product number
C0769
Product name
1,1-Cyclobutanedicarboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$17
Updated
2024/03/01
TCI Chemical
Product number
C0769
Product name
1,1-Cyclobutanedicarboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$48
Updated
2024/03/01
Alfa Aesar
Product number
A14288
Product name
1,1-Cyclobutanedicarboxylic acid, 99%
Packaging
5g
Price
$43.65
Updated
2024/03/01
Alfa Aesar
Product number
A14288
Product name
1,1-Cyclobutanedicarboxylic acid, 99%
Packaging
25g
Price
$122.65
Updated
2024/03/01
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1,1-Cyclobutanedicarboxylic acid Chemical Properties,Usage,Production

Uses

1,1-Cyclobutanedicarboxylic Acid(5445-51-2) is used in the design, studies and structural model of antitumor dicycloplatin a clinical cancer drug. Hydrolysis mechanism of second-generation anticancer drug carboplatin.

Chemical Properties

white fine crystalline powder

Definition

ChEBI: Cyclobutane-1,1-dicarboxylic acid is a cyclobutanedicarboxylic acid. It is a conjugate acid of a cyclobutane-1,1-dicarboxylate(1-).

Application

1,1-Cyclobutanedicarboxylic acid can be used as:
A reactant to synthesize lithium coordination polymer by treating with lithium carbonate.
A ligand to prepare various lanthanide metal-organic frameworks (LnMOFs) via a solvothermal method. Eu+3 based MOF is applicable as a selective chemical sensor for detecting CH3OH due to its high luminescence quantum yield.
It can also be used as a starting material in the synthesis of carboplatin (cis-diammine(1,1-cyclobutanedicarboxyl-ate)platinum(II)).

1,1-Cyclobutanedicarboxylic acid Preparation Products And Raw materials

Raw materials

Sodium ethoxide Sodium Methoxide Diethyl azodicarboxylate Government regulation 1-Bromo-3-chloropropane

Preparation Products

ZENIPLATIN Cyclobutanecarboxylic acid Carboplatin ENLOPLATIN
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View Lastest Price from 1,1-Cyclobutanedicarboxylic acid manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
1,1-Cyclobutanedicarboxylic acid 5445-51-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-08
WUHAN FORTUNA CHEMICAL CO., LTD
Product
1,1-Cyclobutanedicarboxylic acid 5445-51-2
Price
US $0.00/MG
Min. Order
100MG
Purity
98.0%
Supply Ability
1kg/month
Release date
2022-12-29
Hebei Dangtong Import and export Co LTD
Product
1,1-Cyclobutanedicarboxylic acid 5445-51-2
Price
US $20.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
300tons
Release date
2024-09-12

5445-51-2, 1,1-Cyclobutanedicarboxylic acidRelated Search:

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