ChemicalBook > CAS DataBase List > HEMOCYANIN, KEYHOLE LIMPET

HEMOCYANIN, KEYHOLE LIMPET

Product Name
HEMOCYANIN, KEYHOLE LIMPET
CAS No.
9013-72-3
Chemical Name
HEMOCYANIN, KEYHOLE LIMPET
Synonyms
KLH;HEMOCYANIN;haemocyanin;HeMocyanins;blue carrier;HEMOCYANIN-HG;Keyhole limpet;BLUE CARRIER(R);HEMOCYANIN TYPE VIII;KLH, BES/Mg2+ Buffer
CBNumber
CB2327970
Formula Weight
0
MOL File
Mol file
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HEMOCYANIN, KEYHOLE LIMPET Property

storage temp. 
2-8°C
solubility 
H2O: soluble
form 
PBS solution
color 
Off-white to gray
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Safety

Risk Statements 
52/53
Safety Statements 
23-24/25-61
WGK Germany 
1
10-21
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
374817
Product name
Hemocyanin, Keyhole Limpet, Megathura crenulata, Glycerol
Purity
Hemocyanin, Keyhole Limpet, Megathura crenulata, Glycerol, is a large, multi-subunit, oxygen-carrying, metalloprotein that is used as a carrier protein in the production of antibodies.
Packaging
1g
Price
$1710
Updated
2024/03/01
Sigma-Aldrich
Product number
374805
Product name
Hemocyanin, Keyhole Limpet,
Packaging
250mg
Price
$311
Updated
2023/06/20
Sigma-Aldrich
Product number
374805
Product name
Hemocyanin, Keyhole Limpet, Megathura crenulata
Purity
Hemocyanin, Keyhole Limpet, Megathura crenulata, CAS 9013-72-3, is a large, multi-subunit, oxygen-carrying, metalloprotein that is used as a carrier protein in the production of antibodies.
Packaging
1g
Price
$1010
Updated
2023/06/20
Sigma-Aldrich
Product number
H8283
Product name
Hemocyanin from Megathura crenulata (keyhole limpet)
Purity
PBS solution
Packaging
50mg
Price
$154
Updated
2024/03/01
Sigma-Aldrich
Product number
H8283
Product name
Hemocyanin from Megathura crenulata (keyhole limpet)
Purity
PBS solution
Packaging
100mg
Price
$261
Updated
2024/03/01
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HEMOCYANIN, KEYHOLE LIMPET Chemical Properties,Usage,Production

Uses

Hemocyanin from Limulus polyphemus hemolymph has been used:

  • in electrophoretic field gradient focusing as a reference standard for optimizing fluorescence quenching for noncolored proteins
  • as standard protein for pH based crystallization screening experiments
  • in peptide conjugation studies

Uses

Keyhole limpet hemocyanin (KLH) is a strong and well known immune-stimulant in both experimental animals and humans. It has been used as a hapten carrier protein to enhance antigen-specific T cell priming and is known to stimulate a CD4+ T-cell response.
Hemocyanin was used to study if antipeptide antibodies specifically recognize the l1 protein of the human papilloma virus of type 31. It was also used to study the acid-induced unfolding of didecameric keyhole limpet hemocyanin.

General Description

Gastropod hemocyanins are massive glycoproteins (4 to 8 MDa) designed by an intricate arrangement of 10 subunits that are self-assembled into hollow cylinders 35 nm in diameter.

Biochem/physiol Actions

The largest hemocyanin molecules consisting of 48 (8 × 6) subunits are present in horseshoe crabs (Limulus polyphemus) have up to eight distinct subunits type (6 × subunit type I, 8 × II, 2 × IIA, 8 × IIIA, 8 × IIIB, 8 × IV, 4 × V, 4 × VI).

HEMOCYANIN, KEYHOLE LIMPET Preparation Products And Raw materials

Raw materials

Preparation Products

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9013-72-3, HEMOCYANIN, KEYHOLE LIMPETRelated Search:


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  • Supplementary Products
  • Serum Proteins
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  • Enzymes, Inhibitors, and Substrates
  • Antibodies
  • Antibody Purification and Characterization
  • Application Index
  • Biochemicals and Reagents
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  • Application Index
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