ChemicalBook > CAS DataBase List > Tos-PEG5-CH2CO2H
Tos-PEG5-CH2CO2H
- Product Name
- Tos-PEG5-CH2CO2H
- CAS No.
- 2028284-73-1
- Chemical Name
- Tos-PEG5-CH2CO2H
- Synonyms
- Tos-PEG4-CH2COOH;Tos-PEG5-CH2CO2H;Tos-PEG5-CH2COOH;14-(Tosyloxy)-3,6,9,12-tetraoxatetradecanoic acid;14-(Tosyloxy)-3,6,9,12-tetraoxatetradecan-1-oic Acid;14-[(4-methylbenzenesulfonyl)oxy]-3,6,9,12-tetraoxatetradecanoic acid;Acetic acid, 2-[2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]ethoxy]-
- CBNumber
- CB23364037
- Molecular Formula
- C17H26O9S
- Formula Weight
- 406.45
- MOL File
- 2028284-73-1.mol
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Tos-PEG5-CH2CO2H Property
- Boiling point:
- 567.7±50.0 °C(Predicted)
- Density
- 1.260±0.06 g/cm3(Predicted)
- pka
- 3.39±0.10(Predicted)
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-23360
- Product name
- Tos-PEG5-CH2CO2H
- Purity
- 96%
- Packaging
- 250mg
- Price
- $350
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-23360
- Product name
- Tos-PEG5-CH2CO2H
- Purity
- 96%
- Packaging
- 500mg
- Price
- $560
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-23360
- Product name
- Tos-PEG5-CH2CO2H
- Purity
- 96%
- Packaging
- 1g
- Price
- $880
- Updated
- 2021/12/16
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Tos-PEG5-CH2CO2H Chemical Properties,Usage,Production
Description
Tos-PEG5-CH2CO2H is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Tos-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6
Tos-PEG5-CH2CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
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Tos-PEG5-CH2CO2H Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@combi-blocks.com
- Country
- United States
- ProdList
- 6618
- Advantage
- 69
2028284-73-1, Tos-PEG5-CH2CO2HRelated Search:
Tos-PEG4-acid
Tos-PEG5 t-butyl ester
Tos-PEG2-CH2CO2tBu
Tos-PEG2-t-butyl ester
Tos-PEG4-CH2CO2H
Tos-PEG4-t-butyl ester
Tos-PEG6-t-Butyl ester
Tos-PEG3-CH2CO2tBu
Tos-PEG5-CH2CO2t-butyl ester
Tos-PEG3-CH2CO2H