5-Bromoisatoic anhydride

Product Name: 5-Bromoisatoic anhydride
CAS No.: 4692-98-2
Chemical Name: 5-Bromoisatoic anhydride
Synonyms: AKOS BBS-00002893;5-Bromoisatoicacid;5-BROMOISATOIC ANHYDRIDE;5-Bromoisoatoic anhydride;5-BromoisatoicAnhydride>5-Bromoisatoic anhydride,97%;5-BROMOISATOIC ANHYDRIDE 90%;5-Bromoisatoic anhydride 95+%;5-Bromoisatoic anhydride, 90% min;5-BROMOISATOIC ANHYDRIDE, TECH., 90%
CBNumber: CB2341787
Molecular Formula: C8H4BrNO3
Formula Weight: 242.03
MOL File: 4692-98-2.mol

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5-Bromoisatoic anhydride Property

Melting point:: 280-285 °C (dec.) (lit.)
Density: 1.826±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Dimethylformamide
form: powder to crystal
pka: 9.81±0.20(Predicted)
color: White to Light yellow to Light orange
CAS DataBase Reference: 4692-98-2(CAS DataBase Reference)

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Safety

Hazard Codes: T,Xi
Risk Statements: 61-20/21-36/37/38
Safety Statements: 53-23-36/37/39-45
WGK Germany: 3
Hazard Note: Irritant
HazardClass: IRRITANT, IRRITANT-HARMFUL
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 477702
Product name: 5-Bromoisatoic anhydride
Purity: 97%
Packaging: 5g
Price: $320
Updated: 2023/06/20

TCI Chemical

Product number: B3659
Product name: 5-Bromoisatoic Anhydride
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $134
Updated: 2025/07/31

TRC

Product number: B684653
Product name: 5-Bromoisatoic anhydride
Packaging: 100mg
Price: $75
Updated: 2021/12/16

ChemScene

Product number: CS-W017781
Product name: 6-Bromo-2H-benzo[d][1,3]oxazine-2,4(1H)-dione
Purity: 97.56%
Packaging: 25g
Price: $78
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB42908
Product name: 5-Bromoisatoic anhydride
Packaging: 5G
Price: $100
Updated: 2021/12/16

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5-Bromoisatoic anhydride Chemical Properties,Usage,Production

Chemical Properties

Off-white to salmon powder

Uses

5-Bromoisatoic anhydride is an important chemical raw material and pharmaceutical intermediate, mainly used in laboratory research and development processes and chemical production processes.

Preparation

5-Bromoisatoic anhydride is prepared from 5-bromo indole by stirring in a 4:1 mixture of DMF/H2O for 16 h at room temperature.
1HNMR(DMSO-d6): δ 11.85 (s, br., 1H), 7.96 (dd, J = 0.8, 8.7 Hz, 1H), 7.87 (dd, J = 2.3, 8.7 Hz, 1H), 7.09 (dd, J = 8.8, 0.8 Hz, 1H).

Synthesis

87-48-9

4692-98-2

General procedure for the synthesis of 6-bromo-2H-benzo[d][1,3]oxazine-2,4(1H)-dione using 5-bromoindigo red as starting material: 5-bromoindigo red (II) (20.0 g, 88.49 mmol) was uniformly dispersed in dichloromethane (300 mL), and m-chloroperoxybenzoic acid (22.91 g, 132.73 mmol) was added in batches at room temperature. at room temperature. The reaction mixture was stirred at room temperature for 2 h. The reaction progress was monitored by thin layer chromatography (TLC) to confirm the completion of the reaction. Subsequently, the reaction system was cooled to 10°C with continuous stirring and sodium bisulfite solution was slowly added dropwise until the starch potassium iodide paper no longer showed color. The reaction solution was concentrated by rotary evaporation to remove dichloromethane, 50 mL of water was added to mix well with the residue, and then saturated sodium bicarbonate solution was added dropwise until no bubbles were produced. The resulting solid was collected by filtration, washed with a small amount of water and dried at 50 °C to give 20.99 g of 5-bromoisatoindirubic anhydride (III) in 98% yield.

References

[1] Patent: CN106632276, 2017, A. Location in patent: Paragraph 0112; 0113; 0114
[2] Angewandte Chemie, 1980, vol. 92, # 3, p. 196 - 197
[3] Catalysis Science and Technology, 2015, vol. 5, # 10, p. 4830 - 4838
[4] Patent: CN103570726, 2016, B. Location in patent: Paragraph 0085; 0086; 0087
[5] Journal fuer Praktische Chemie (Leipzig), 1886, vol. <2> 33, p. 36

5-Bromoisatoic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-Bromoisatoic anhydride manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5-Bromo isatoic anhydride 4692-98-2
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 100kg
Release date: 2025-08-29

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 5-Bromoisatoic anhydride 4692-98-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-08-19

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5-Bromoisatoic anhydride 4692-98-2
Price: US $8.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-28

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5-BROMOISATOIC ANHYDRIDE

BROMO-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE

6-BROMO-1,2-DIHYDRO-4 H-3,1-BENZOXAZINE-2,4-DIONE

6-BROMO-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE

AKOS BBS-00002893

5-Bromoisatoic anhydride 95+%

6-bromo-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione

5-BROMOISATOIC ANHYDRIDE, TECH., 90%

5-Bromoisatoicacid

5-Bromoisatoic anhydride,97%

2H-3,1-Benzoxazine-2,4(1H)-dione, 6-bromo-

6-Bromo-2H-3,1-benzoxazine-2,4(1H)-dione, 6-Bromo-1H-benzo[d][1,3]oxazine-2,4-dione

5-BROMOISATOIC ANHYDRIDE 90%

6-Bromo-2H-3,1-benzoxazine-2,4(1H)-dione

5-BroMoisatoic Anhydride, 98.0%(LC&T

6-bromo-1H-3,1-benzoxazine-2,4-dione

6-bromo-1H-3,1-benzoxazine-2,4-quinone

5-Bromoisoatoic anhydride

6-bromo-2H-benzo[d][1,3]oxazine-2,4(1H)-dione

5-Bromoisatoic anhydride, 90% min

5-BromoisatoicAnhydride&gt

4692-98-2

C8H4BrNO3

ARYL HALIDE

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts