2-Amino-5-bromo-3-methylpyridine

Product Name: 2-Amino-5-bromo-3-methylpyridine
CAS No.: 3430-21-5
Chemical Name: 2-Amino-5-bromo-3-methylpyridine
Synonyms: 5-BROMO-3-METHYLPYRIDIN-2-AMINE;5-BROMO-3-METHYL-PYRIDIN-2-YLAMINE;2-Amina-5-bromo;TIMTEC-BB SBB003694;2-Amino-5-bromo-3-methyl;2-AMINO-5-BROMO-3-PICOLINE;2-Amina-5-bromo-3-picoline;2-Amino-5-bromo-3-picoline,98%;5-Bromo-3-methyl-2-pyridinamine;2-AMINO-3-METHYL-5-BROMOPYRIDINE
CBNumber: CB2409508
Molecular Formula: C6H7BrN2
Formula Weight: 187.04
MOL File: 3430-21-5.mol

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2-Amino-5-bromo-3-methylpyridine Property

Melting point:: 88-95 °C(lit.)
Boiling point:: 250.0±35.0 °C(Predicted)
Density: 1.5672 (rough estimate)
refractive index: 1.5500 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Chloroform, Methanol
form: Solid
pka: 4.96±0.49(Predicted)
color: Yellow
Sensitive: Hygroscopic
BRN: 386426
InChI: InChI=1S/C6H7BrN2/c1-4-2-5(7)3-9-6(4)8/h2-3H,1H3,(H2,8,9)
InChIKey: KBLGGRWUEVCNPY-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(Br)C=C1C
CAS DataBase Reference: 3430-21-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-36/37
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29333999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 525537
Product name: 2-Amino-5-bromo-3-methylpyridine
Purity: 97%
Packaging: 5g
Price: $115
Updated: 2025/07/31

Sigma-Aldrich

Product number: 525537
Product name: 2-Amino-5-bromo-3-methylpyridine
Purity: 97%
Packaging: 1g
Price: $49
Updated: 2023/06/20

TCI Chemical

Product number: A2154
Product name: 2-Amino-5-bromo-3-methylpyridine
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $27
Updated: 2025/07/31

TCI Chemical

Product number: A2154
Product name: 2-Amino-5-bromo-3-methylpyridine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $74
Updated: 2025/07/31

TRC

Product number: A601829
Product name: 2-Amino-5-bromo-3-methylpyridine
Packaging: 10g
Price: $165
Updated: 2021/12/16

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2-Amino-5-bromo-3-methylpyridine Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

2-Amino-5-bromo-3-methylpyridine may be used to synthesize:

5-bromo-2-chloro-3-methylpyridine
2-azidopyridine 1-oxide
2-amino-5-bromo-3-methylpyridine 1-oxide
2,5-dibromo-3-methyl pyridine
ethyl-3,6-dibromo-8-methylimidazo[1,2-a]pyridine-2-carboxylate

General Description

2-Amino-5-bromo-3-methylpyridine can be prepared from 2-amino-3-methylpyridine, via bromination.

Synthesis

1603-40-3

3430-21-5

General procedure for the synthesis of 2-amino-3-methyl-5-bromopyridine from 2-amino-3-methylpyridine: Bromine (15.4 mL, 0.30 mol) was slowly added dropwise to an anhydrous dichloromethane (1000 mL) solution of 2-amino-3-methylpyridine (32.44 g, 0.30 mol) under stirring at 0-2 °C for 1 hour. The cooling bath was then removed and the yellow suspension was allowed to continue stirring at room temperature for 3 hours and 40 minutes. Upon completion of the reaction, the mixture was alkalized to pH 9 with 2N sodium hydroxide solution (145 mL) and subsequently treated with a mixture of saturated aqueous sodium bicarbonate (100 mL) and saturated aqueous sodium thiosulfate (10 mL). The organic layer was separated, washed with brine, dried over magnesium sulfate and concentrated to give the brown solid product 2-amino-3-methyl-5-bromopyridine (56.83 g, 102% yield), which could be used in the next reaction without further purification.

References

[1] Patent: WO2004/13139, 2004, A2. Location in patent: Page 25-26
[2] Tetrahedron Letters, 2009, vol. 50, # 9, p. 1007 - 1009
[3] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001, vol. 40, # 11, p. 1129 - 1131
[4] Patent: CN105348177, 2016, A. Location in patent: Paragraph 0012; 0016
[5] Journal of Medicinal Chemistry, 2012, vol. 55, # 4, p. 1682 - 1697

2-Amino-5-bromo-3-methylpyridine Preparation Products And Raw materials

Raw materials

Hydrogen peroxide Sodium sulfite 2-Amino-3-picoline Hydrogen bromide Ethyl acetate Bromine Acetic acid

Preparation Products

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2-Amino-5-bromo-3-methylpyridine Suppliers

Americas 1 Belgium 3 Canada 1 China 312 Czech Republic 1 Europe 3 France 2 Germany 7 India 59 Japan 2 Switzerland 2 The Netherlands 1 United Kingdom 22 United States 60 Global 476

Toronto Research Chemicals

Tel: --
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Email: info@trc-canada.com
Country: Canada
ProdList: 6038
Advantage: 71

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View Lastest Price from 2-Amino-5-bromo-3-methylpyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-Amino-5-bromo-3-methylpyridine 3430-21-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 10000KGS
Release date: 2025-05-30

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Amino-5-bromo-3-methylpyridine 3430-21-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-28

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Amino-5-bromo-3-methylpyridine 3430-21-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-12

3430-21-5, 2-Amino-5-bromo-3-methylpyridineRelated Search:

2-Amino-5-bromo-3-(hydroxymethyl)pyridine 6-Bromo-3,4-dihydro-1H-[1,8]naphthyridin-2-one Methyl 2-amino-5-bromonicotinate 5-BROMO-2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE 2-Amino-5-bromonicotinic acid 5-BROMO-1H-PYRROLO[2 , 3-B]PYRIDIN-2(3H)-ONE (2-AMINO-5-BROMOPYRIDIN-3-YL)METHANOL HYDROBROMIDE 2-AMINO-5-BROMO-3,4-DIMETHYLPYRIDINE 2-Amino-5-bromo-3-methylpyridine 2-Acetylamino-5-bromo-3-methylpyridine 5-AMINO-2-BROMO-3-METHYLPYRIDINE,5-AMINO-2-BROMO-3-PICOLINE (5-AMINO-2-BROMO-3-METHYLPYRIDINE) 2-Amino-3-bromo-5-methylpyridine 4-Bromo-2-methyl-3-pyridinamine 4-AMINO-5-BROMO-3-METHYLPYRIDINE 3-Amino-2-bromo-4-methylpyridine 5-Amino-2-bromo-4-methylpyridine 2-AMINO-3-BROMO-4-METHYLPYRIDINE 3-Amino-5-bromo-2-methylpyridine

2-AMINO-5-BROMO-3-METHYLPYRIDINE

2-AMINO-5-BROMO-3-PICOLINE

2-AMINO-3-METHYL-5-BROMOPYRIDINE

2-AMINO-5-BROMO-3-METHYLPYRIDINE 98%

5-Bromo-3-methyl-2-pyridinamine

2-Amino-5-bromo-3-methyl

2-Amina-5-bromo-3-picoline

2-AMINO-5-BROMO-3-PICOLINE (2-AMINO-5-BROMO-3-METHYLPYRIDINE)

JR-8255, 2-Amino-5-bromo-3-methylpyridine, 97%

2-Amino-5-bromo-3-picoline,98%

5-Bromo-3-methylpyridin-2-amine ,98%

2-Amino-5-bromo-3-methylpyridine ,98%

2-PyridinaMine, 5-broMo-3-Methyl-

TIMTEC-BB SBB003694

5-BROMO-3-METHYLPYRIDIN-2-AMINE

5-BROMO-3-METHYL-PYRIDIN-2-YLAMINE

6-aMino-3-broMo-5-Methylpyridine

2-Amino-5-bromo-3-picoline, 5-Bromo-3-methylpyridin-2-amine

2-AMino-5-broMo-3-Methylpyridine SynonyMs 5-BroMo-3-Methylpyridin-2-aMine

2-Amino-5-bromo-3-methylpyridine,97%

5-broMo-3-Methyl-2-aMinopyridine

2-Amina-5-bromo

2-Amino-5-bromo-3-methylpyridine &gt

2-Amino-5-bromo-3-methylpyridine ISO 9001：2015 REACH

5-Bromo-3-methyl-pyridine-2-ylamine

"2-Amino-3-methyl-5-bromopyridine 13C4, 15N"

3-methyl-2-amino-5-bromo pyridine

3430-21-5

30-21-5

430-21-5

C6H7N2Br

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyridines

Pyridines, Pyrimidines, Purines and Pteredines

Amines

Pyridines

Heterocyclic Compounds

Chemical Amines

Anilines, Amides & Amines

Bromine Compounds

Miscellaneous Compounds

Bromopyridines

Pyridine

Amines and Anilines

Heterocycles

C6Heterocyclic Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Halopyridines

Bases & Related Reagents

Heterocyclic

Nucleotides

Boronic Acid