ChemicalBook > CAS DataBase List > LUMIFLAVINE

LUMIFLAVINE

Product Name
LUMIFLAVINE
CAS No.
1088-56-8
Chemical Name
LUMIFLAVINE
Synonyms
SKL056;Lumiflavin;LUMIFLAVINE;Lumilactoflavin;Lumiflavin (III);LUMIFLAVINE Impurity;Vitamin B2 Impurity A;Riboflavin EP Impurity A;7,8,10-TRIMETHYLISOALLOXAZINE;Inhibitor,Lumiflavine,inhibit
CBNumber
CB2450641
Molecular Formula
C13H12N4O2
Formula Weight
256.26
MOL File
1088-56-8.mol
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LUMIFLAVINE Property

Melting point:
320°; mp 330°
storage temp. 
2-8°C
solubility 
Methanol (Very Slightly, Heated, Sonicated), Trifluoroacetic Acid (Very Slightly
form 
powder
Density 
1.48 g/cm3
pka
10.05±0.70(Predicted)
color 
Dark Yellow to Dark Green
Merck 
13,5621
Stability:
Stable. Incompatible with strong oxidizing agents.
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
OK4800000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20645
Product name
Lumiflavine
Purity
≥95%
Packaging
5mg
Price
$40
Updated
2024/03/01
Cayman Chemical
Product number
20645
Product name
Lumiflavine
Purity
≥95%
Packaging
10mg
Price
$76
Updated
2024/03/01
Cayman Chemical
Product number
20645
Product name
Lumiflavine
Purity
≥95%
Packaging
25mg
Price
$146
Updated
2024/03/01
Cayman Chemical
Product number
20645
Product name
Lumiflavine
Purity
≥95%
Packaging
50mg
Price
$274
Updated
2024/03/01
TRC
Product number
L473900
Product name
Lumiflavin
Packaging
10mg
Price
$190
Updated
2021/12/16
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LUMIFLAVINE Chemical Properties,Usage,Production

Chemical Properties

deep yellow powder

Uses

Lumiflavin is a toxic photolysis product of vitamin B2 (R415000).

Definition

ChEBI: Lumiflavin is a compound showing yellow-green fluorescence, formed by a photolysis of riboflavin in alkaline solution.

in vivo

Lumiflavin (8 mg/kg, i.p., once a day for 25 days) has a synergistic cytotoxic effect on an ovarian cancer nude mice model by enhancing the DNA‐damage response and increasing the apoptotic protein expression[2].
Lumiflavin (4-16 mg/kg, s.c., once a day for 25 days) combined with DDP reduces tumor weight and inhibits tumor growth[3].

Animal Model:Nude mice[3]
Dosage:4-16 mg/kg
Administration:s.c., once a day for 25 days
Result:Reduced tumor weight and inhibited tumor growth curve combined with DDP in a dose-dependent manner.

Purification Methods

Lumiflavin forms orange crystals upon recrystallisation from 12% aqueous AcOH, or from formic acid. It sublimes at high vacuum. It is freely soluble in CHCl3, but not very soluble in H2O and most organic solvents. In H2O and CHCl3 solution it has a green fluorescence. UV has max at 269, 355 and 445nm ( 38,800, 11,700 and 11,800, respectively) in 0.1N NaOH and 264, 373 and 440nm ( 34,700, 11,400 and 10,400, respectively) in 0.1N HCl, while the UV in CHCl3 has max at 270, 312, 341, 360, 420, 445 and 470nm. [Hemmerich et al. Helv Chim Acta 39 1242 1956, Holiday & Stern Chem Ber 67 1352 1834, Yoneda et al. Chem Pharm Bull Jpn 20 1832 1972, Birch & Moye J Chem Soc 2622 1958, Fluorescence: Kuhn & Moruzzi Chem Ber 67 888 1934, Beilstein 26 III/IV 2539.]

LUMIFLAVINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from LUMIFLAVINE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Lumiflavin 1088-56-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-13
Career Henan Chemical Co
Product
LUMIFLAVINE 1088-56-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
10 tons
Release date
2020-03-04

1088-56-8, LUMIFLAVINERelated Search:

Minoxidil Vitamin A Flavin adenine dinucleotide disodium salt FLAVIN ADENINE DINUCLEOTIDE LUMIFLAVINE Riboflavin 5'-Monophosphate Sodium Salt RIBOFLAVINE TETRABUTYRATE Riboflavin ethanol lumiflavine RO 08-2750 RIBOFLAVIN GALACTOSIDE RIBOFLAVIN 5'-PHOSPHATE SODIUM SALT HYDRATE RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT Riboflavin 5'-(dihydrogen phosphate), sodium salt LABOTEST-BB LT00244821 3-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDROBENZO[G]PTERIDIN-10(2H)-YL)PROPANENITRILE riboflavin-5'-monobutyrate LABOTEST-BB LT00848265

  • (3h,10h)-dione,7,8,10-trimethyl-benzo(g)pteridine-4
  • Lumiflavin
  • Lumiflavin (III)
  • Lumilactoflavin
  • 7,8,10-TRIMETHYLBENZO[G]PTERIDINE-2,4(3H,10H)-DIONE
  • 7,8,10-TRIMETHYLISOALLOXAZINE
  • 7,8,10-Trimethylbenzo[g]pteridine-2,4(3H,10H)-dione, 7,8,10-Trimethylisoalloxazine
  • 7,8,10-Trimethyl-2,3,4,10-tetrahydrobenzo[g]pteridine-2,4-dione
  • 7,8,10-Trimethyl-2,3,4,10-tetrahydropyrimido[4,5-b]quinoxaline-2,4-dione
  • 7,8-Dimethyl-10-methylbenzo[g]pteridine-2,4(3H,10H)-dione
  • 7,8,10-trimethylbenzo[g]pteridine-2,4-dione
  • 7,8,10-trimethylbenzo[g]pteridine-2,4-quinone
  • Lumiflavine,7,8,10-Trimethylbenzo[g]pteridine-2,4(3H,10H)-dione, 7,8,10-Trimethylisoalloxazine
  • 4-hydroxy-7,8,10-triMethylbenzo[g]pteridin-2(10H)-one
  • LUMIFLAVINE
  • Riboflavin Impurity 3 (Lumiflavine)
  • Riboflavin EP Impurity A
  • Riboflavin Sodium Phosphate Impurity 5(Riboflavin Sodium Phosphate EP Impurity E)
  • Benzo[g]pteridine-2,4(3H,10H)-dione, 7,8,10-trimethyl-
  • Riboflavin EP Impurity A (Riboflavin Sodium Phosphate EP Impurity E, Lumiflavine)
  • Riboflavin Sodium Phosphate EP Impurity E
  • SKL056
  • Inhibitor,Lumiflavine,inhibit
  • Riboflavin Impurity 1 (Riboflavin EP Impurity A)
  • Riboflavin(VB2) EP Impurity A（Riboflavin Sodium Phosphate EP Impurity E）
  • LUMIFLAVINE Impurity
  • Vitamin B2 Impurity A
  • 1088-56-8