Suprofen

Product Name: Suprofen
CAS No.: 40828-46-4
Chemical Name: Suprofen
Synonyms: Suprol;TN 762;r25061;Anemet;Srendam;Suprocil;Topalgic;Profenal;Profenol;maldocil
CBNumber: CB2496867
Molecular Formula: C14H12O3S
Formula Weight: 260.31
MOL File: 40828-46-4.mol

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Suprofen Property

Melting point:: 278°C
Boiling point:: 373.57°C (rough estimate)
Density: 1.2959 (rough estimate)
refractive index: 1.5050 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 0.5 mg/ml
pka: 3.91(at 25℃)
form: Powder
color: White to off-white
Water Solubility: soluble
CAS DataBase Reference: 40828-46-4(CAS DataBase Reference)

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Safety

RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 2934990002
Toxicity: LD50 (7 days post-drug) in mice, rats, guinea pigs, dogs (mg/kg): 590, 353, 280, 160 orally (Niemegeers)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1495
Product name: Suprofen
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $80.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML1495
Product name: Suprofen
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $261
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1642507
Product name: Suprofen
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200MG
Price: $252
Updated: 2024/03/01

Cayman Chemical

Product number: 21350
Product name: Suprofen
Purity: ≥98%
Packaging: 5mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 21350
Product name: Suprofen
Purity: ≥98%
Packaging: 10mg
Price: $115
Updated: 2024/03/01

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Suprofen Chemical Properties,Usage,Production

Description

Suprofen is an arylpropionic acid analgesic/antiinflammatory agent with close structural resemblance to ketoprofen. It is more potent in many assays than indomethacin and ketoprofen and appears better tolerated.

Chemical Properties

Off-White to Light-Brown

Originator

Janssen (Belgium)

Uses

Prostaglandin biosynthesis inhibitor. Analgesic

Uses

Bridged pseudopelletierine derivative; specific serotonin (5HT3) receptor antagonist. Antiemetic.

Definition

ChEBI: An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.

brand name

Profenal (Alcon);Algiamida;Algiasdi;Bordol;Erdol;Masterfen;Sufenid;Supranol;Surfex;MALDOCIL.

Veterinary Drugs and Treatments

Suprofen is a non-steroidal anti-inflammatory agent similar to flurbiprofen. Suprofen and flurbiprofen are phenylalkanoic acids that inhibit the cyclo-oxygenase enzymes responsible for conversion of arachadonic acid from cell membranes into various prostaglandins. These prostaglandins mediate certain aspects of ocular inflammation including disruption of the blood-aqueous barrier, uveal vasodilation, increases in intraocular pressure, and leakage of white blood cells and protein from uveal vessels into the aqueous humor. Prostaglandins cause iris sphincter constriction (miosis) independent of cholinergic mechanisms. Suprofen can inhibit this intraocular miosis and may also be useful in the management of uveal inflammation (usually in addition to topical steroids).

Suprofen Preparation Products And Raw materials

Raw materials

Osmium tetroxide dolasetron Dihydropyran 4-METHYLMORPHOLINE-4-OXIDE SOLUTION Sodium borohydride Silver tetrafluoroborate Double ring Sodium periodate ethyl cyclopent-3-ene-1-carboxylate Furan

Preparation Products

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Suprofen Suppliers

Canada 1 China 97 Europe 2 Germany 1 India 2 Japan 1 South Korea 1 United Kingdom 5 United States 23 Global 133

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View Lastest Price from Suprofen manufacturers

Hebei Mujin Biotechnology Co.,Ltd

Product: Suprofen 40828-46-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-09-01

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Suprofen 40828-46-4
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%-102%
Supply Ability: 100G
Release date: 2021-06-09

Hebei Weibang Biotechnology Co., Ltd

Product: Suprofen 40828-46-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-20

40828-46-4, SuprofenRelated Search:

Flurbiprofen (S)-(+)-2-Phenylpropionic acid Thifensulfuron Propionic acid Cephalothin sodium Tetrahydrothiophene 4-Methoxyphenylacetone Suprofen-D3 LC-R 505 Cliprofen Suprofen SUPROFEN USP(CRM STANDARD) suprofen acyl glucuronide (S)-(+)-Suprofen,(S)-Suprofen suprofen-copper(II) complex (R)-Suprofen,R(-)-Suprofen Dearboxy suprofen 4-((5-Bromo-2-thienyl)carbonyl)-alpha-methylbenzeneacetic acid

Dolasetron Methanesulformte

MDL-73147EF：Anzemet

2-[4-(Thiophene-2-carbonyl)phenyl]propanoic acid

a-Methyl-p-(2-thenoyl)phenylacetic acid

2-[4-(thiophene-2-carbonyl)phenyl]propionic acid

1H-Indole-3-carboxylic acid(2α，6α，8α，9αβ)-octahydro-3-oxo-2，6-methano-2H-quinolizin-8-yl ester

Suprofen (200 mg)

α-Methyl-4-(2-thienylcarbonyl)benzeneacetic Acid

para-(2-Thenoyl) hydratropic acid

Maldocil,Masterfen,Supranol,Supro,

a-Methyl-4-(2-thienylcarbonyl)benzeneacetic Acid

Masterfen

Srendam

Sulprotin

Suprocil

Suprol

Sutoprofen

Topalgic

DOLASETRON(FREE BASE)

Benzeneacetic acid, a-methyl-4-(2-thienylcarbonyl)- (9CI)

NSC 303611

Profenal

Profenol

Racemic suprofen

Sulproltin

TN 762

(+-)-2-(p-(2-thenoyl)phenyl)propionicacid

alpha-methyl-4-(2-thienylcarbonyl)-benzeneaceticaci

alpha-methyl-4-(2-thienylcarbonyl)benzeneaceticacid

maldocil

p-(2-thenoyl)-hydratropicaci

p-(2-thenoyl)hydratropicacid

r25061

Suprofen

BENZENEACETICACID,A-METHYL-4-(2-THIENYLCARBONYL)

Anemet

MDL 73147

Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl Ester 1H-Indole-3-carboxylic Acid Stereoisomer

2-(4-Thiophen-2-ylcarbonylphenyl)propanoic acid

Benzeneacetic acid, α-methyl-4-(2-thienylcarbonyl)-

2-[4-(2-Thienylcarbonyl)phenyl]propanoic Acid

Suprofen USP/EP/BP

Suprofen (TN-762)

Suprofen (1642507)

2-(3-(Thiophene-2-carbonyl)phenyl)propanoic acid

Ranelic Acid Impurity 9

Suprofen, 10 mM in DMSO

40828-46-4

115952-12-2

115956-12-0

Inhibitors

Heterocyclic Compounds

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals