ChemicalBook > CAS DataBase List > 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride

6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride

Product Name
6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
CAS No.
57196-62-0
Chemical Name
6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
Synonyms
6-Methoxy-1,2,3,4-tetrahydrois;6-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HCL;ISOQUINOLINE 1,2,3,4-TETRAHYDRO-6-METHOXY HCL SALT;6-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE;1,2,3,4-tetrahydro-6-methoxyisoquinoline hydrochloride;6-Methoxy-1,2,3,4-tetraihydroisoquinoline hydrochloride;6-Methoxy-1,2,3,4-tetrahydroisoquinolinehydrochloride,95%;Isoquinoline, 1,2,3,4-tetrahydro-6-Methoxy-, hydrochloride;Isoquinoline,1,2,3,4-tetrahydro-6-methoxy-,hydrochloride(1:1);Better offer for 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
CBNumber
CB2501596
Molecular Formula
C10H14ClNO
Formula Weight
199.68
MOL File
57196-62-0.mol
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6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride Property

Melting point:
230-232.5°C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
Appearance
White to off-white Solid
CAS DataBase Reference
57196-62-0
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-51
HazardClass 
IRRITANT
HS Code 
2933491090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M268803
Product name
6-Methoxy-1,2,3,4-tetrahydroisoquinolineHydrochloride
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
M268803
Product name
6-Methoxy-1,2,3,4-tetrahydroisoquinolineHydrochloride
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
M268803
Product name
6-Methoxy-1,2,3,4-tetrahydroisoquinolineHydrochloride
Packaging
500mg
Price
$110
Updated
2021/12/16
Ark Pharm
Product number
P000066897
Product name
6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
Purity
97%
Packaging
250mg
Price
$9
Updated
2021/12/16
AK Scientific
Product number
J96311
Product name
6-Methoxy-1,2,3,4-tetrahydroisoquinolinehydrochloride
Packaging
250mg
Price
$18
Updated
2021/12/16
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6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride Chemical Properties,Usage,Production

Synthesis

50-00-0

55-81-2

57196-62-0

To a stirred suspension of 4-methoxyphenethylamine (50.4 g, 0.33 mol, 1.0 eq.) in water (40 mL) was slowly added 37% aqueous formaldehyde (27.5 mL, 1.1 eq.) with continuous stirring for 20 minutes. Subsequently, concentrated hydrochloric acid (80 mL) was added dropwise to the reaction mixture and the mixture was heated to reflux and maintained for 1 hour. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated to dryness in a rotary evaporator. The resulting residue was purified by recrystallization from acetone to afford 6-methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride as a white solid (60.1 g, 90% yield). The product did not require further purification and could be used directly in the subsequent reaction. Mass spectrometry analysis showed that the MH+ peak was located at 164.

References

[1] Patent: WO2003/99786, 2003, A2. Location in patent: Page 35

6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride Preparation Products And Raw materials

Raw materials

Ethanol (3-Methoxyphenyl)acetonitrile Paraformaldehyde Tetrahydrofuran Lithium Aluminum Hydride Hydrochloric acid

Preparation Products

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6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride Suppliers

Canada 1 China 119 Germany 1 India 3 United Kingdom 3 United States 18 Global 145
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
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View Lastest Price from 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride 57196-62-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-28
Career Henan Chemical Co
Product
6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride 57196-62-0
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
10000kgs
Release date
2020-01-09

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  • 6-Methoxy-1,2,3,4-tetraihydroisoquinoline hydrochloride
  • ISOQUINOLINE 1,2,3,4-TETRAHYDRO-6-METHOXY HCL SALT
  • 6-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HCL
  • 6-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE
  • Isoquinoline,1,2,3,4-tetrahydro-6-methoxy-,hydrochloride(1:1)
  • 6-Methoxy-1,2,3,4-tetrahydroisoquinolinehydrochloride,95%
  • Better offer for 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
  • 57196-62-0
  • API intermediates