ChemicalBook > CAS DataBase List > 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE

2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE

Product Name
2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE
CAS No.
433-06-7
Chemical Name
2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE
Synonyms
100532;TRIFLUORETHYLTOSYLATE;Trifluoroethyltosylate;Azithromycin Impurity 74;TRIFLUOROETHANOL TOSYLATE;2,2,2-TRIFLUOROETHYL P-TO;2,2,2-trifluoroethyl ester;2,2,2-TRIFLUOROETHYL TOSYLATE;o-(p-tosyl)a,a,a,-trifluoroethanol;Trifluoroethyl p-toluene sulfonate
CBNumber
CB2670852
Molecular Formula
C9H9F3O3S
Formula Weight
254.23
MOL File
433-06-7.mol
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2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE Property

Melting point:
36-38 °C(lit.)
Boiling point:
87-92 °C0.1 mm Hg(lit.)
Density 
1 g/cm3
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Sparingly), Methanol (Sparingly)
form 
Solid
color 
White to Off-White
Sensitive 
Moisture Sensitive
BRN 
2699394
Stability:
Hygroscopic
InChI
1S/C9H9F3O3S/c1-7-2-4-8(5-3-7)16(13,14)15-6-9(10,11)12/h2-5H,6H2,1H3
InChIKey
IGKCQDUYZULGBM-UHFFFAOYSA-N
SMILES
Cc1ccc(cc1)S(=O)(=O)OCC(F)(F)F
CAS DataBase Reference
433-06-7(CAS DataBase Reference)
NIST Chemistry Reference
Ethanol, 2,2,2-trifluoro-, 4-methylbenzenesulfonate(433-06-7)
EPA Substance Registry System
Ethanol, 2,2,2-trifluoro-, 4-methylbenzenesulfonate (433-06-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
TSCA 
TSCA listed
HazardClass 
IRRITANT
HS Code 
29049090
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
177822
Product name
2,2,2-Trifluoroethyl p-toluenesulfonate
Purity
99%
Packaging
50g
Price
$77.7
Updated
2025/07/31
TCI Chemical
Product number
T1516
Product name
2,2,2-Trifluoroethyl p-Toluenesulfonate
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$101
Updated
2025/07/31
TRC
Product number
T790230
Product name
2,2,2-TrifluoroethylTosylate
Packaging
100g
Price
$110
Updated
2021/12/16
TRC
Product number
T790230
Product name
2,2,2-TrifluoroethylTosylate
Packaging
250g
Price
$225
Updated
2021/12/16
AK Scientific
Product number
V2170
Product name
Trifluoroethyltosylate
Packaging
500g
Price
$257
Updated
2021/12/16
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2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE Chemical Properties,Usage,Production

Chemical Properties

WHITE CRYSTALLINE SOLID

Uses

2,2,2-Trifluoroethyl Tosylate is a trifluoroethylation agent used in the preparation of 2,2,2-trifluoroethyl phenyl sulfone, a potential 2,2,2-trifluoroethyl pronucleophile.

Synthesis

2,2,2-Trifluoroethyl p-Toluenesulfonate is easily prepared by treating 2,2,2-trifluoroethanol with p-Toluenesulfonyl Chloride in pyridine or in aqueous acetone containing NaOH.

Precautions

Quite stable; can be handled without any special technique and stored at room temperature; use in a fume hood.

2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE Suppliers

Jiaxing Fubo Biotechnology Co., Ltd.
Tel
18157018567
Fax
+86-570-7805617
Email
sales@fluorio.com
Country
China
ProdList
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SHANG FLUORO
Tel
021-65170832 15601903708
Email
qinba_1@163.com
Country
China
ProdList
405
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60
Shandong Zhishang Chemical Co. LTD
Tel
15689709505 15508639737
Email
2138533552@qq.com
Country
China
ProdList
70
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58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
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View Lastest Price from 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
2,2,2-trifluoroethyl tosylate 433-06-7
Price
US $3.90-5.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-06-13
Henan Aochuang Chemical Co.,Ltd.
Product
2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE 433-06-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2025-04-01
Hebei Chuanghai Biotechnology Co,.LTD
Product
Trifluoroethyl p-toluene sulfonate 433-06-7
Price
US $9.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2024-08-20

433-06-7, 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATERelated Search:


  • TRIFLUORETHYLTOSYLATE
  • TRIFLUOROETHANOL TOSYLATE
  • P-TOLUENESULFONIC ACID 2,2,2-TRIFLUOROETHYL ESTER
  • 2,2,2-trifluoro-, p-toluenesulfonate
  • o-(p-tosyl)a,a,a,-trifluoroethanol
  • 2,2,2-Trifluoroethyl 4-methylbenzenesulphonate, 2,2,2-Trifluoroethyl tosylate
  • 2,2,2-Trifluoroethyl toluene-4-sulphonate 98%
  • 2,2,2-Trifluoroethyl p-toluenesulfonate 99%
  • 2,2,2-Trifluoroethyl <i>p</i>-Toluenesulfonate
  • 2,2,2-TRIFLUOROETHYL P-TOLUENESULFOTE
  • 2,2,2-TRIFLUOROETHYL TOSYLATE
  • 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE
  • 2,2,2-TRIFLUOROETHYL P-TOLUENESULPHONATE
  • 2,2,2-TRIFLUOROETHYL-4-TOLUENESULFONATE
  • 2,2,2-TRIFLUOROETHYL 4-TOLUENESULPHONATE
  • 2,2,2-TRIFLUOROETHYL P-TOLUENESULF
  • 2,2,2-trifluoroethyl ester
  • 2,2,2-trifluoro-ethano4-methylbenzenesulfonate
  • Ethanol, 2,2,2-trifluoro-, p-toluenesulfonate
  • 2,2,2-TRIFLUOROETHYL 4-METHYLBENZENESULFONATE
  • 2,2,2-Trifluoroethyl p-toluenesulfonate, 98+%
  • 2,2,2-Trifluoroethyl 4-toluenesulphonate 98%
  • 2,2,2-Trifluoroethyl4-toluenesulphonate98%
  • p-Toluenesulphonic acid 2,2,2-trifluoroethyl ester
  • 4-Toluenesulfonic acid 2,2,2,-trifluoroethyl ester
  • Trifluoroethyltosylate
  • 4-Methylbenzenesulfonic acid 2,2,2-trifluoroethyl ester
  • p-Methylbenzenesulfonic acid 2,2,2-trifluoromethyl
  • 2. 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE
  • 2,2,2-trifluoroethyl 4-methylbenzene-1-sulfonate
  • 100532
  • 2,2,2-Trifluoro-1-(4-methylbenzenesulfonate)-ethanol
  • Ethanol, 2,2,2-trifluoro-, 1-(4-methylbenzenesulfonate)
  • Trifluoroethyl p-toluene sulfonate
  • 2,2,2-TRIFLUOROETHYL P-TO
  • 2,2,2-Trifluoroethyl p-toluenesulfonate CasNo.433-06-7
  • 2,2,2-Trifluoroethyl toluene-4-sulphonate
  • Azithromycin Impurity 74
  • 433-06-7
  • 43-06-7
  • C9H9F3O3S
  • CH3C6H4SO3CH2CF3
  • Fluorinated Building Blocks
  • Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds
  • Organic Building Blocks
  • Sulfur Compounds
  • Tosylates
  • Building Blocks
  • Fluorinated Building Blocks
  • Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds
  • Synthetic Organic Chemistry
  • Organic Building Blocks
  • Sulfur Compounds
  • Tosylates
  • API intermediates
  • blocks
  • BuildingBlocks
  • FluoroCompounds