ChemicalBook > CAS DataBase List > 2-AMINO-5-FLUOROPHENOL

2-AMINO-5-FLUOROPHENOL

Product Name
2-AMINO-5-FLUOROPHENOL
CAS No.
53981-24-1
Chemical Name
2-AMINO-5-FLUOROPHENOL
Synonyms
EOS-61433;2-AMINO-5-FLUOROPHEN;5-Fluoro-2-aMinophenol;2-AMINO-5-FLUOROPHENOL;2-azanyl-5-fluoro-phenol;4-Fluoro-2-hydroxyaniline;2-Amino-5-fluorophenol98%;Phenol, 2-amino-5-fluoro-;2- aMino-5-difluoro phenol;2-Amino-5-fluorophenol 98%
CBNumber
CB2716633
Molecular Formula
C6H6FNO
Formula Weight
127.12
MOL File
53981-24-1.mol
More
Less

2-AMINO-5-FLUOROPHENOL Property

Melting point:
38°C
Boiling point:
246.1±25.0 °C(Predicted)
Density 
1.347±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO, Methanol
pka
8.76±0.10(Predicted)
form 
Solid
color 
Dark Beige
Water Solubility 
Slightly soluble in water.
Sensitive 
Air Sensitive
InChI
InChI=1S/C6H6FNO/c7-4-1-2-5(8)6(9)3-4/h1-3,9H,8H2
InChIKey
IIDUNAVOCYMUFB-UHFFFAOYSA-N
SMILES
C1(O)=CC(F)=CC=C1N
CAS DataBase Reference
53981-24-1(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
29089990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
A2300
Product name
2-Amino-5-fluorophenol
Purity
>97.0%(GC)
Packaging
1g
Price
$38
Updated
2025/07/31
TCI Chemical
Product number
A2300
Product name
2-Amino-5-fluorophenol
Purity
>97.0%(GC)
Packaging
5g
Price
$110
Updated
2025/07/31
TRC
Product number
A609600
Product name
2-Amino-5-fluorophenol
Packaging
1g
Price
$45
Updated
2021/12/16
TRC
Product number
A609600
Product name
2-Amino-5-fluorophenol
Packaging
5g
Price
$50
Updated
2021/12/16
Usbiological
Product number
002246
Product name
2-Amino-5-fluorophenol
Packaging
1g
Price
$319
Updated
2021/12/16
More
Less

2-AMINO-5-FLUOROPHENOL Chemical Properties,Usage,Production

Chemical Properties

Dark Beige Solid

Uses

2-Amino-5-fluorophenol is a fluoroaniline metabolite. 2-Amino-5-fluorophenol is used as organic intermediate. To synthesize the intermediate (2-amino-5-fluorophenol-N, N, O-triacetic acid trimethyl ester) of indicator which used in the determination Mg2+ by NMR, three feasible reactions were experimentally carried out, such as alkaline hydrolysis, catalytic hydrogenation and esterification.

Synthesis

446-36-6

53981-24-1

The general procedure for the synthesis of 2-amino-5-fluorophenol from 5-fluoro-2-nitrophenol is as follows: 5-fluoro-2-nitrophenol (2.50 g, 15.9 mmol, commercially available from e.g., Aldrich) was dissolved in ethanol (50 ml), and 10% palladium-carbon catalyst (980 mg) was added for the hydrogenation reaction, which lasted for 1.5 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated. The solid residue obtained was dissolved in ether, followed by addition of an equal volume of cyclohexane. The ether was removed by vacuum distillation at room temperature to give a light gray solid product. The product was filtered and washed with cyclohexane to give 2-amino-5-fluorophenol (1.90 g, 94% yield). Elemental analysis measured values: C, 56.4; H, 4.8; N, 10.9. theoretical values (C6H6FNO): C, 56.7; H, 4.8; N, 11.0%.

References

[1] Journal of Medicinal Chemistry, 2015, vol. 58, # 24, p. 9742 - 9753
[2] Patent: WO2010/94643, 2010, A1. Location in patent: Page/Page column 46
[3] Patent: US5238908, 1993, A
[4] Patent: US5393735, 1995, A
[5] Chemistry - A European Journal, 2011, vol. 17, # 33, p. 9076 - 9082

2-AMINO-5-FLUOROPHENOL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-AMINO-5-FLUOROPHENOL Suppliers

Americas 1 Belgium 1 Canada 3 China 191 Europe 3 France 2 Germany 7 India 6 Italy 1 Japan 1 The Netherlands 1 United Kingdom 18 United States 38 Global 273
xiamen hongyi
Tel
18060930853
Email
18060930853@163.com
Country
China
ProdList
16
Advantage
58
Henan yingchuang
Tel
16650708709
Fax
qq:778660296
Email
hnyingchuang@163.com
Country
China
ProdList
3965
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16075
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
PSN Pharmaceutical Technology Co., Ltd.
Tel
86-25-57062118
Fax
86-25-57065896
Email
sales@jspsn.com
Country
China
ProdList
496
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2864
Advantage
52
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Aloespharm Co., Ltd.
Tel
021-20960837
Fax
021-20960837
Email
market@aloespharm.com
Country
China
ProdList
1302
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Shanghai Aspire Biological Technology Co., Ltd.
Tel
021-61317773
Fax
021-61486878
Email
sales@aspirebio.com
Country
China
ProdList
2880
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10263
Advantage
55
Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
ProdList
5734
Advantage
55
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4641
Advantage
60
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Shanghai Na Qian Chemical Technology Co. Ltd.
Tel
13598610367
Fax
QQ:2468833170
Email
2841375912@qq.com
Country
China
ProdList
2788
Advantage
52
Changzhou Tianrui Pharmaceutical Technology Co., Ltd.
Tel
0519-85386832 13382812559
Fax
0519-85386832
Email
sales@cztrchem.com
Country
China
ProdList
1185
Advantage
56
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Beijing Xinsavi Chemical Technology Co., Ltd.
Tel
010-56218822 13717722232
Fax
010-56218800
Email
xinsavichem@163.com
Country
China
ProdList
3201
Advantage
56
Beijing Holiyang Chemical Co. Ltd.
Tel
13718199399
Fax
QQ : 206661479
Email
holiyangchem@163.com
Country
China
ProdList
3280
Advantage
56
Shanghai YouPeng Chemical Co. Ltd.
Tel
021-69005955 13701776567
Fax
021-69005775
Email
youpengchem@163.com
Country
China
ProdList
4161
Advantage
56
Sichuan Hainuowei Technology Co. Ltd.
Tel
13708085536 13708085536
Fax
QQ : 121102042
Email
hanovichem@163.com
Country
China
ProdList
3282
Advantage
56
Shanghai TongYuan Chemical Co., Ltd.
Tel
021-021-69182866 13701855675
Fax
021-69182022
Email
tongyuanchem@126.com
Country
China
ProdList
4193
Advantage
58
Shanghai Kaisai Chemical Co., Ltd
Tel
021-33516722 13701817765
Fax
021-33516776
Email
kaisaichem@163.com
Country
China
ProdList
4610
Advantage
58
Beijing HuaYangZhicheng Technology Co., Ltd.
Tel
13716033033
Fax
010-56276266
Email
hanchochem@163.com
Country
China
ProdList
2960
Advantage
50
Shanghai LanRun Chemical Co., Ltd.
Tel
021-69515658 ; 69515628 13701998368
Fax
021-69515998
Email
longrunchem@163.com
Country
China
ProdList
3786
Advantage
50
Shanghai Rolead Chemical Technology Co., Ltd.
Tel
021-69992220 13701886816
Fax
021-69992237
Email
roleadchem@163.com
Country
China
ProdList
4613
Advantage
50
Shanghai Kangtuo Chemical Co., Ltd.
Tel
021-69185552 13701777608
Fax
021-69186006
Email
kangtuochem@163.com
Country
China
ProdList
4232
Advantage
55
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Anqing CHICO Pharmaceutical Co., Ltd.
Tel
13585175604 13057662806
Fax
+86-25-52261140
Email
sales@chicopharm.com
Country
China
ProdList
500
Advantage
65
More
Less

View Lastest Price from 2-AMINO-5-FLUOROPHENOL manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-AMINO-5-FLUOROPHENOL 53981-24-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-22
Career Henan Chemical Co
Product
2-AMINO-5-FLUOROPHENOL 53981-24-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-06-27

53981-24-1, 2-AMINO-5-FLUOROPHENOLRelated Search:

2-AMINO-5-FLUOROPHENOL Levofloxacin 2-Acetonyloxy-3,4-difluoro nitrobenzene 4-FLUORO-2-METHOXYANILINE 5-Fluoro-2-nitroanisole Levofloxacin carboxylic acid 2,3-DIFLUORO-6-NITROPHENOL 5-Bromo-2-fluorophenol Ipodate Sodium Marbofloxacin 3-Amino-4-fluorophenol 4-AMINO-2-FLUOROPHENOL,4-Amino-2-fluorophenol 98%,4-Amino-2-fluorophenol98% 4-Amino-3-Fluorophenol 3-Fluoro-4-Aminophenol,4-AMINO-3-FLUOROPHENOL,4-Amino-3-fluorophenol98%,4-Amino-3-fluorophenol 98%,4-AMINO-3-FLUOROPHENOL, 98% MIN. 2-Amino-4-fluorophenol 98%,2-Amino-4-fluorophenol98%,2-AMINO-4-FLUOROPHENOL 4-Amino-3-fluorophenol, HCl,4-Amino-3-fluorophenol,hydrochloride METHYL 2-(5-FLUORO-2-NITROPHENOXY)ACETATE 2-AMINO-3-FLUOROPHENOL 5-FLUORO-2-NITROPHENYL 2-CHLOROBENZOATE

  • 2-AMINO-5-FLUOROPHENOL
  • 2-Amino-5-fluorophenol 98%
  • 2-Amino-5-fluorophenol98%
  • 2-Amino-5-fluorophenol 97+%
  • 2-azanyl-5-fluoro-phenol
  • 2-Amino-5-fluorophenol ,90%
  • 2-AMINO-5-FLUOROPHEN
  • 4-Fluoro-2-hydroxyaniline
  • (4-Fluoro-2-hydroxyphenyl)aMine
  • 5-Fluoro-2-aMinophenol
  • 2- aMino-5-difluoro phenol
  • EOS-61433
  • 2-Amino-5-fluorophenol &gt
  • Phenol, 2-amino-5-fluoro-
  • 2-AMINO-5-FLUOROPHENOL ISO 9001：2015 REACH
  • 53981-24-1 2-AMINO-5-FLUOROPHENOL
  • 2-Amino-5-Fluorophenol, 10 mM in DMSO
  • 53981-24-1
  • Aromatic Phenols
  • Amines, Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Phenol&Thiophenol&Mercaptan
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals