ChemicalBook > CAS DataBase List > 2-Methoxythiophene

2-Methoxythiophene

Product Name: 2-Methoxythiophene
CAS No.: 16839-97-7
Chemical Name: 2-Methoxythiophene
Synonyms: Methoxythiophene;2-METHOXYTHIOPHENE;Thiophene, 2-methoxy-;2-Methoxythiophene>2-Methoxythiophene 97%;2-Methoxythiophene,99%;2-Methoxythiophene,97%;METHYL 2-THIENYL ETHER;2-Methoxythiophene ISO 9001：2015 REACH
CBNumber: CB2748272
Molecular Formula: C5H6OS
Formula Weight: 114.17
MOL File: 16839-97-7.mol

Less

2-Methoxythiophene Property

Boiling point:: 151-152 °C/762 mmHg (lit.)
Density: 1.133 g/mL at 25 °C (lit.)
refractive index: n20/D 1.528(lit.)
Flash point:: 110 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform, Methanol (Slightly)
form: clear liquid
color: Colorless to Light yellow to Light orange
BRN: 106271
InChI: InChI=1S/C5H6OS/c1-6-5-3-2-4-7-5/h2-4H,1H3
InChIKey: OKEHURCMYKPVFW-UHFFFAOYSA-N
SMILES: C1(OC)SC=CC=1
LogP: 2.130
CAS DataBase Reference: 16839-97-7(CAS DataBase Reference)
NIST Chemistry Reference: 2-Methoxythiophene(16839-97-7)

Less

Safety

Risk Statements: 10
Safety Statements: 16
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
HazardClass: 3
PackingGroup: III
HS Code: 29349990

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 331597
Product name: 2-Methoxythiophene
Purity: 97%
Packaging: 5g
Price: $63
Updated: 2025/07/31

TCI Chemical

Product number: M1030
Product name: 2-Methoxythiophene
Purity: >98.0%(GC)
Packaging: 5g
Price: $97
Updated: 2025/07/31

TCI Chemical

Product number: M1030
Product name: 2-Methoxythiophene
Purity: >98.0%(GC)
Packaging: 25g
Price: $330
Updated: 2025/07/31

TRC

Product number: M271690
Product name: 2-Methoxythiophene
Packaging: 10g
Price: $360
Updated: 2021/12/16

TRC

Product number: M271690
Product name: 2-Methoxythiophene
Packaging: 1g
Price: $110
Updated: 2021/12/16

Less

2-Methoxythiophene Chemical Properties,Usage,Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

2-Methoxythiophene was used in thermal reaction (60°C) of (C₅Me₅)Rh(PMe₃)(Ph)H.

Synthesis Reference(s)

Journal of the American Chemical Society, 75, p. 3697, 1953 DOI: 10.1021/ja01111a027

General Description

2-Methoxythiophene is a heterocyclic methyl enol ether and its reaction with o-quinone monoimide was studied. The intramolecular and intermolecular geometries of crystals of 2-methoxythiophene were investigated. Kinetics of the hydronium-ion catalysed hydrolysis of 2-methoxythiophene was reported.

Synthesis

1003-09-4

124-41-4

16839-97-7

Example 1 Preparation of 2-methoxythiophene: In a reactor, 300 g of 2-bromothiophene (1.84 mol), 2.64 g of copper(I) bromide (CuBr, 1 mol%), 18.4 g of polyethylene glycol dimethyl ether (PEG DME 500, 2 mol%), and 660 g of a methanolic solution of sodium methanolate (30% concentration, precursor concentration of 30.6%) were added in sequence. The mixture was heated to 90 °C for the reaction and the progress of the reaction was monitored by gas chromatography (GC) until the conversion was >98% (total reaction time 8h). Upon completion of the reaction, the reaction mixture was slowly poured into 500 g of water and filtered through Decalite. Subsequently, the aqueous phase was extracted twice with methyl tert-butyl ether (MTBE, 150 g each time). The organic phases were combined and purified by vacuum fractional distillation to give a final 182 g of 2-methoxythiophene (1.59 mol, 86.4% yield) with a GC purity of >99% (% area).

References

[1] Patent: US2008/71084, 2008, A1. Location in patent: Page/Page column 3-4
[2] Synthetic Communications, 1990, vol. 20, # 2, p. 213 - 216
[3] Tetrahedron, 1992, vol. 48, # 17, p. 3633 - 3652
[4] Research on Chemical Intermediates, 2015, vol. 41, # 11, p. 8651 - 8664

2-Methoxythiophene Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2-Methoxythiophene Suppliers

Americas 1 Austria 1 Belgium 2 Canada 1 China 157 Europe 1 France 2 Germany 8 India 7 Italy 1 Japan 3 Slovakia 2 Switzerland 3 The Netherlands 1 United Kingdom 13 United States 32 USA 1 Global 236

Entrenture (Lanzhou) Biomedical Technology Co., Ltd

Tel: 13919408782
Email: 1297709337@qq.com
Country: China
ProdList: 465
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

Puyang Huicheng Electronic Material Co. Ltd.

Tel: 0393-0393-0393-8910800 15039333257
Fax: 0393-8912775
Email: info@huichengchem.com
Country: China
ProdList: 569
Advantage: 64

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Beijing Isomersyn Technology CO;LTD

Tel: 010-82954736 13391601435
Email: sales@isomersyn.com
Country: China
ProdList: 3295
Advantage: 57

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Wuhan Kemi-Works Chemical Co., Ltd

Tel: 027-85736489
Fax: 86-27-85736485
Email: info@kemiworks.net
Country: China
ProdList: 540
Advantage: 57

Aemon Chemical

Tel: 0086-755-86198205
Email: acinfo@aemonchem.com
Country: China
ProdList: 1931
Advantage: 57

ZhengZhou HuaWen Chemical Co.Ltd

Tel: 0370-2785118 17550508557
Fax: QQ：3470079902
Email: 675141927@qq.com
Country: China
ProdList: 3199
Advantage: 55

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9658
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Huainan Kedi Chemical Factory

Tel: 0554-2106669
Fax: 0554-2666215
Email: sales1@kedichem.com
Country: China
ProdList: 4924
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Zhengzhou ALFA Chemical Co., Ltd.

Tel: 0371-53732842 15981811963
Fax: 0371-86239377
Email: 1758257485@qq.com
Country: China
ProdList: 950
Advantage: 56

Zhengzhou HongSheng Pharmaceutical Co., Ltd.

Tel: 0371-0371-13526885213 15637198702
Fax: 0371-63709726
Email: hsyykjchem@163.com
Country: China
ProdList: 3852
Advantage: 58

Shanghai Aspire Biological Technology Co., Ltd.

Tel: 021-61317773
Fax: 021-61486878
Email: sales@aspirebio.com
Country: China
ProdList: 2880
Advantage: 58

Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 18013166090
Fax: 0512-87182056
Email: lingling.qi@yacoo.com.cn
Country: China
ProdList: 6295
Advantage: 60

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5219
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 15121041756
Email: xingui2022@126.com
Country: China
ProdList: 9986
Advantage: 58

Tianjin Anhao Biological Technology Co., Ltd.

Tel
Email: sales@ahpharmatech.com
Country: China
ProdList: 5734
Advantage: 55

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Zhengzhou BenHe Chemical Products Co., Ltd.,

Tel: 17703858868
Email: 1819929654@qq.com
Country: China
ProdList: 288
Advantage: 50

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Zhengzhou KeYulong chemical products Co., Ltd

Tel: 17319789407 17319789407
Fax: 0371-53335504
Email: Keyulongchem@163.com
Country: China
ProdList: 1987
Advantage: 55

Shanghai Uchem Inc.

Tel: 15618758386; 15618758386
Fax: QQ:3004479444
Email: sales3@myuchem.com
Country: China
ProdList: 1988
Advantage: 55

Shanghai eliv pharmaceutical Co.,Ltd.

Tel: 021-50158063
Fax: 021-6153 1846
Email: sales@elivpharma.com
Country: China
ProdList: 477
Advantage: 58

Less

View Lastest Price from 2-Methoxythiophene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Methoxythiophene 16839-97-7
Price: US $9.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-29

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Methoxythiophene 16839-97-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

Henan Fengda Chemical Co., Ltd

Product: 2-Methoxythiophene 16839-97-7
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-30

16839-97-7, 2-MethoxythiopheneRelated Search:

2-Methylthiophene POLY(ETHYLENE GLYCOL) METHYL ETHER ACRYLATE (Trifluoromethoxy)benzene 4-Methoxybenzyl cyanide Guaiacol Anisole p-Anisaldehyde p-Anisidine 4-Methoxyphenol Methoxythiophene,95%,3-METHOXYTHIOPHENE ETHYL 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE 5-CHLORO-4-METHOXYTHIOPHENE-3-CARBONYLCH,5-CHLORO-4-METHOXYTHIOPHENE-3-CARBONYL CHLORIDE,2-Chloro-3-methoxythiophene-4-carbonyl chloride 5-BROMO-4-METHOXYTHIOPHENE-3-CARBOXYLIC ACID,2-BROMO-3-METHOXYTHIOPHENE-4-CARBOXYLIC ACID 2-Aminopyrimidine-5-boronic Acid Pinacol Ester 2-CHLORO-3-METHOXYTHIOPHENE-4-CARBOXYLIC ACID,5-CHLORO-4-METHOXYTHIOPHENE-3-CARBOXYLIC ACID 2-Methoxythiophene-2-carboxylic acid methylester,METHYL 3-METHOXYTHIOPHENE-2-CARBOXYLATE,3-METHOXYTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER Methyl 4-bromo-3-methoxythiophene-2-carboxylate 98%,METHYL 4-BROMO-3-METHOXYTHIOPHENE-2-CARBOXYLATE 3,4-Dimethoxythiophene

Methoxythiophene

2-METHOXYTHIOPHENE

METHYL 2-THIENYL ETHER

Thiophene, 2-methoxy-

2-Methoxythiophene,97%

2-Methoxythiophene,99%

2-Methoxythiophene 97%

2-Methoxythiophene&gt

2-Methoxythiophene ISO 9001：2015 REACH

16839-97-7

6839-97-7

Building Blocks

Thiophenes

Heterocyclic Building Blocks

Heterocyclic Compounds

Building Blocks

Heterocyclic Building Blocks

Thiophenes

Thiophene Series