2-Methoxythiophene
- Product Name
- 2-Methoxythiophene
- CAS No.
- 16839-97-7
- Chemical Name
- 2-Methoxythiophene
- Synonyms
- Methoxythiophene;2-METHOXYTHIOPHENE;Thiophene, 2-methoxy-;2-Methoxythiophene>2-Methoxythiophene 97%;2-Methoxythiophene,99%;2-Methoxythiophene,97%;METHYL 2-THIENYL ETHER;2-Methoxythiophene ISO 9001：2015 REACH
- CBNumber
- CB2748272
- Molecular Formula
- C5H6OS
- Formula Weight
- 114.17
- MOL File
- 16839-97-7.mol
2-Methoxythiophene Property
- Boiling point:
- 151-152 °C/762 mmHg (lit.)
- Density
- 1.133 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.528(lit.)
- Flash point:
- 110 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform, Methanol (Slightly)
- form
- clear liquid
- color
- Colorless to Light yellow to Light orange
- BRN
- 106271
- InChI
- InChI=1S/C5H6OS/c1-6-5-3-2-4-7-5/h2-4H,1H3
- InChIKey
- OKEHURCMYKPVFW-UHFFFAOYSA-N
- SMILES
- C1(OC)SC=CC=1
- LogP
- 2.130
- CAS DataBase Reference
- 16839-97-7(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Methoxythiophene(16839-97-7)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
N-Bromosuccinimide Price
- Product number
- 331597
- Product name
- 2-Methoxythiophene
- Purity
- 97%
- Packaging
- 5g
- Price
- $63
- Updated
- 2025/07/31
- Product number
- M1030
- Product name
- 2-Methoxythiophene
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $97
- Updated
- 2025/07/31
- Product number
- M1030
- Product name
- 2-Methoxythiophene
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $330
- Updated
- 2025/07/31
- Product number
- M271690
- Product name
- 2-Methoxythiophene
- Packaging
- 10g
- Price
- $360
- Updated
- 2021/12/16
- Product number
- M271690
- Product name
- 2-Methoxythiophene
- Packaging
- 1g
- Price
- $110
- Updated
- 2021/12/16
2-Methoxythiophene Chemical Properties,Usage,Production
Chemical Properties
CLEAR YELLOW LIQUID
Uses
2-Methoxythiophene was used in thermal reaction (60°C) of (C5Me5)Rh(PMe3)(Ph)H.
Synthesis Reference(s)
Journal of the American Chemical Society, 75, p. 3697, 1953 DOI: 10.1021/ja01111a027
General Description
2-Methoxythiophene is a heterocyclic methyl enol ether and its reaction with o-quinone monoimide was studied. The intramolecular and intermolecular geometries of crystals of 2-methoxythiophene were investigated. Kinetics of the hydronium-ion catalysed hydrolysis of 2-methoxythiophene was reported.
Synthesis
1003-09-4
124-41-4
16839-97-7
Example 1 Preparation of 2-methoxythiophene: In a reactor, 300 g of 2-bromothiophene (1.84 mol), 2.64 g of copper(I) bromide (CuBr, 1 mol%), 18.4 g of polyethylene glycol dimethyl ether (PEG DME 500, 2 mol%), and 660 g of a methanolic solution of sodium methanolate (30% concentration, precursor concentration of 30.6%) were added in sequence. The mixture was heated to 90 °C for the reaction and the progress of the reaction was monitored by gas chromatography (GC) until the conversion was >98% (total reaction time 8h). Upon completion of the reaction, the reaction mixture was slowly poured into 500 g of water and filtered through Decalite. Subsequently, the aqueous phase was extracted twice with methyl tert-butyl ether (MTBE, 150 g each time). The organic phases were combined and purified by vacuum fractional distillation to give a final 182 g of 2-methoxythiophene (1.59 mol, 86.4% yield) with a GC purity of >99% (% area).
References
[1] Patent: US2008/71084, 2008, A1. Location in patent: Page/Page column 3-4
[2] Synthetic Communications, 1990, vol. 20, # 2, p. 213 - 216
[3] Tetrahedron, 1992, vol. 48, # 17, p. 3633 - 3652
[4] Research on Chemical Intermediates, 2015, vol. 41, # 11, p. 8651 - 8664
2-Methoxythiophene Preparation Products And Raw materials
Raw materials
Preparation Products
2-Methoxythiophene Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from 2-Methoxythiophene manufacturers
- Product
- 2-Methoxythiophene 16839-97-7
- Price
- US $9.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-29
- Product
- 2-Methoxythiophene 16839-97-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-26
- Product
- 2-Methoxythiophene 16839-97-7
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30