ChemicalBook > CAS DataBase List > 2-Iodopyridine

2-Iodopyridine

Product Name
2-Iodopyridine
CAS No.
5029-67-4
Chemical Name
2-Iodopyridine
Synonyms
JACS-5029-67-4;2-lodopyridine;2-IODOPYRIDINE;2-Pyridyl iodide;Pyridine, 2-iodo-;2-Iodine Pyridine;2-Iodopyridine 98%;2-Iodopyridine 2-IODOPYRIDINE, 95+%;2-Iodopyridine≥ 98% (GC)
CBNumber
CB2754297
Molecular Formula
C5H4IN
Formula Weight
205
MOL File
5029-67-4.mol
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2-Iodopyridine Property

Melting point:
118-120℃
Boiling point:
52 °C (lit.)
Density 
1.928 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.6320(lit.)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Solid
pka
pK1:1.82(+1) (25°C)
color 
Pale yellow
Water Solubility 
Slightly soluble in water.
Sensitive 
Light Sensitive
InChIKey
CCZWSTFVHJPCEM-UHFFFAOYSA-N
CAS DataBase Reference
5029-67-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
558761
Product name
2-Iodopyridine
Purity
98%
Packaging
5g
Price
$134.8
Updated
2024/03/01
Sigma-Aldrich
Product number
558761
Product name
2-Iodopyridine
Purity
98%
Packaging
1g
Price
$76.9
Updated
2023/06/20
TCI Chemical
Product number
I0533
Product name
2-Iodopyridine (stabilized with Na2S2O3)
Purity
>98.0%(GC)
Packaging
5g
Price
$65
Updated
2024/03/01
TCI Chemical
Product number
I0533
Product name
2-Iodopyridine (stabilized with Na2S2O3)
Purity
>98.0%(GC)
Packaging
25g
Price
$259
Updated
2024/03/01
Alfa Aesar
Product number
H63062
Product name
2-Iodopyridine, 95%
Packaging
5g
Price
$76.1
Updated
2024/03/01
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2-Iodopyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow liquid

Uses

2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.

Uses

2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.

Reactions

2-Iodopyridine and 3-alkoxy-2-iodopyridines are oxidized by DMDO to give PyIO2 , which serve as oxidants for alcohols and sulfides.
In palladium-catalyzed aminocarbonylation of 2-iodopyridine, 3-iodopyridine and iodopyrazine were coupled with CO and various primary and secondary amines. The biologically relevant N-substituted nicotinamides and 3-pyridyl-glyoxylamides were obtained from 3-iodopyridine as a result of simple and double carbon monoxide insertions, respectively. The chemoselectivity towards the ketoamide can be increased by the elevation of CO pressure. On the other hand, N-alkyl and N-aryl-carboxamides were obtained exclusively from CO pressure of 1 to 90 bar by using 2-iodopyridine and iodopyrazine.

Pd-catalyzed aminocarbonylation of 2-iodopyridine and 3-iodopyridine with primary and secondary amines.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 6757, 1990 DOI: 10.1016/S0040-4039(00)97163-6

General Description

2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.

2-Iodopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Iodopyridine Suppliers

Changzhou Xiaobu Fine Chemicals Co., Ltd
Tel
0512-66388446 15851926283
Email
42050065@qq.com
Country
China
ProdList
61
Advantage
58
Shanghai Jiyu Medical Technology Co., Ltd
Tel
13816953660
Email
wzy@shjypharm.com
Country
China
ProdList
56
Advantage
58
New Energy Chemicals
Tel
0515-82159088 13770142076
Fax
86-0515-8215909
Email
twl@njuchem.com
Country
China
ProdList
205
Advantage
65
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
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View Lastest Price from 2-Iodopyridine manufacturers

Hebei Duling International Trade Co. LTD
Product
2-Iodopyridine 5029-67-4
Price
US $80.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2023-04-26
Hebei Duling International Trade Co. LTD
Product
2-Iodopyridine 5029-67-4
Price
US $80.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2023-04-26
Henan Aochuang Chemical Co.,Ltd.
Product
2-Iodopyridine 5029-67-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-12

5029-67-4, 2-IodopyridineRelated Search:


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