ChemicalBook > CAS DataBase List > 2-Iodopyridine

2-Iodopyridine

Product Name
2-Iodopyridine
CAS No.
5029-67-4
Chemical Name
2-Iodopyridine
Synonyms
JACS-5029-67-4;2-lodopyridine;2-IODOPYRIDINE;2-Pyridyl iodide;Pyridine, 2-iodo-;2-Iodine Pyridine;2-Iodopyridine 98%;2-Iodopyridine 2-IODOPYRIDINE, 95+%;2-Iodopyridine≥ 98% (GC)
CBNumber
CB2754297
Molecular Formula
C5H4IN
Formula Weight
205
MOL File
5029-67-4.mol
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2-Iodopyridine Property

Melting point:
118-120℃
Boiling point:
52 °C (lit.)
Density 
1.928 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.6320(lit.)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Solid
pka
pK1:1.82(＋1) (25°C)
color 
Pale yellow
Water Solubility 
Slightly soluble in water.
Sensitive 
Light Sensitive
InChIKey
CCZWSTFVHJPCEM-UHFFFAOYSA-N
CAS DataBase Reference
5029-67-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
558761
Product name
2-Iodopyridine
Purity
98%
Packaging
5g
Price
$134.8
Updated
2024/03/01
Sigma-Aldrich
Product number
558761
Product name
2-Iodopyridine
Purity
98%
Packaging
1g
Price
$76.9
Updated
2023/06/20
TCI Chemical
Product number
I0533
Product name
2-Iodopyridine (stabilized with Na2S2O3)
Purity
>98.0%(GC)
Packaging
5g
Price
$65
Updated
2024/03/01
TCI Chemical
Product number
I0533
Product name
2-Iodopyridine (stabilized with Na2S2O3)
Purity
>98.0%(GC)
Packaging
25g
Price
$259
Updated
2024/03/01
Alfa Aesar
Product number
H63062
Product name
2-Iodopyridine, 95%
Packaging
5g
Price
$76.1
Updated
2024/03/01
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2-Iodopyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow liquid

Uses

2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.

Uses

2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.

Reactions

2-Iodopyridine and 3-alkoxy-2-iodopyridines are oxidized by DMDO to give PyIO2 , which serve as oxidants for alcohols and sulfides.
In palladium-catalyzed aminocarbonylation of 2-iodopyridine, 3-iodopyridine and iodopyrazine were coupled with CO and various primary and secondary amines. The biologically relevant N-substituted nicotinamides and 3-pyridyl-glyoxylamides were obtained from 3-iodopyridine as a result of simple and double carbon monoxide insertions, respectively. The chemoselectivity towards the ketoamide can be increased by the elevation of CO pressure. On the other hand, N-alkyl and N-aryl-carboxamides were obtained exclusively from CO pressure of 1 to 90 bar by using 2-iodopyridine and iodopyrazine.

Pd-catalyzed aminocarbonylation of 2-iodopyridine and 3-iodopyridine with primary and secondary amines.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 6757, 1990 DOI: 10.1016/S0040-4039(00)97163-6

General Description

2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.

2-Iodopyridine Preparation Products And Raw materials

Raw materials

2-Bromopyridine Hydriodic acid

Preparation Products

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2-Iodopyridine Suppliers

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View Lastest Price from 2-Iodopyridine manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
2-Iodopyridine 5029-67-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-12
Dideu Industries Group Limited
Product
2-Iodopyridine 5029-67-4
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-01
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Iodopyridine 5029-67-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

5029-67-4, 2-IodopyridineRelated Search:

Sulfasalazine 4-Methylpyridine 3-Aminopyridine Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Pyridine Chromium picolinate 2-Chloro-3-cyanopyridine 2,5-Diiodopyridine 2-IODOQUINOLINE 5-BROMO-2-IODOPYRIDINE 97%,5-bromo-2-iodopyridine 97% 5g 4-IODO-PYRIDIN-3-OL 2-IODO-3-METHOXYPYRIDINE 3-CHLORO-4-IODOPYRIDINE 5-AMINO-2-IODOPYRIDINE 99% 2-BOC-AMINO-5-IODOPYRIDINE 2-Fluoro-5-iodopyridine 3-Hydroxy-2-iodo-6-methylpyridine 1-IODOISOQUINOLINE

  • 2-Iodopyridine(stabilizedwithCopperchip)
  • 2-lodopyridine
  • 2-IODOPYRIDINE, 95+%
  • 2-IODOPYRIDINE
  • 2-Pyridyl iodide
  • 2-Iodopyridine&nbsp
  • 2-Iodopyridine (stabilized with Na2S2O3)
  • 2-Iodopyridine 98%
  • 2-Iodopyridine (stabilized with Copper chip), 96.0%(GC)
  • 2-Iodopyridine≥ 98% (GC)
  • JACS-5029-67-4
  • 2-Iodopyridine(stabilizedwithCopperchip)&gt
  • Pyridine, 2-iodo-
  • 2-Iodopyridine ISO 9001：2015 REACH
  • 2-Iodine Pyridine
  • 5029-67-4
  • Iodopyridines
  • Halopyridines
  • Building Blocks
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Pyridines
  • Heterocycle-Pyridine series
  • Halides
  • Pyridines
  • Pyridine
  • Halopyridines
  • Iodopyridines
  • C5Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks