ChemicalBook > CAS DataBase List > Propacetamol

Propacetamol

Product Name
Propacetamol
CAS No.
66532-85-2
Chemical Name
Propacetamol
Synonyms
Propacetamo;Pro-Dafalgan;PROPACETAMOL;Propacatemol;Propacetamol USP/EP/BP;4-Acetamidophenyl N,N-diethylglycinate;4-acetamidophenyl N,N-diethylaminoacetate;N,N-Diethylglycine 4-(acetylamino)phenyl ester;(Diethylamino)acetic acid 4-(acetylamino)phenyl;Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester
CBNumber
CB2759429
Molecular Formula
C14H20N2O3
Formula Weight
264.32
MOL File
66532-85-2.mol
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Propacetamol Property

Melting point:
55-57 °C
Boiling point:
434.5±30.0 °C(Predicted)
Density 
1.132±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
H2O : 100 mg/mL (378.33 mM; Need ultrasonic)
pka
14.20±0.70(Predicted)
form 
Solid
color 
White to off-white
CAS DataBase Reference
66532-85-2(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0015798
Product name
N,N-DIETHYLGLYCINE-4-(ACETYLAMINO)PHENYL ESTER
Purity
95.00%
Packaging
1G
Price
$939.89
Updated
2021/12/16
AvaChem
Product number
3086B
Product name
Propacetamol
Packaging
100mg
Price
$35
Updated
2021/12/16
AvaChem
Product number
3086B
Product name
Propacetamol
Packaging
1g
Price
$95
Updated
2021/12/16
AvaChem
Product number
3086B
Product name
Propacetamol
Packaging
10g
Price
$475
Updated
2021/12/16
AHH
Product number
MT-58176
Product name
Propacetamol
Purity
98%
Packaging
5g
Price
$910
Updated
2021/12/16
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Propacetamol Chemical Properties,Usage,Production

Description

Propacetamol is the prodrug of paracetamol (acetaminophen), used for intravenous administration. It results from eombination of paracetamol and diethylglycine. Causes contact dermatitis and airborne dermatitis in nurses. Allergenic properties are due to the N,N' -diethylglycine moiety, and not to the paracetamol moiety.

Uses

Propacetamol hydrochloride is a water-soluble prodrug for intravenous administration resulting in the liberation of paracetamol.

Definition

ChEBI: Propacetamol is an alpha-amino acid ester.

Contact allergens

Propacetamol is a prodrug of paracetamol (acetaminophen) used for intravenous administration. It results from the combination of paracetamol and diethylglycine. It caused contact (hand and airborne) dermatitis in nurses and acute systemic dermatitis (pompholyx and nummular dermatitis, generalized eczema, urticaria-like eruption) in nurses who had became sick and received intravenous propacetamol. Allergenic properties are due to the N,N-diethylglycine moiety, and not to the paracetamol moiety. Propacetamol is now substituted by a solution of paracetamol in mannitol (Perfalgan?).

Mechanism of action

It is a soluble glycine prodrug derivative of paracetamol. It is used as hydrochloride, for intramuscular or intravenous application and is rapidly metabolized to free paracetamol .

Propacetamol Preparation Products And Raw materials

Raw materials

Preparation Products

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Propacetamol Suppliers

LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
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View Lastest Price from Propacetamol manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Propacetamol 66532-85-2
Price
US $9.00/KG
Min. Order
1KG
Purity
99.8%
Supply Ability
100tons
Release date
2024-08-16
Dideu Industries Group Limited
Product
Propacetamol 66532-85-2
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-15

66532-85-2, PropacetamolRelated Search:


  • PROPACETAMOL
  • 4-Acetamidophenyl diethylaminoacetate hydrochloride
  • Pro-Dafalgan
  • N,N-Diethylglycine 4-(acetylamino)phenyl ester
  • (Diethylamino)acetic acid 4-(acetylamino)phenyl
  • 4-Acetamidophenyl N,N-diethylglycinate
  • 4-acetamidophenyl N,N-diethylaminoacetate
  • Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester
  • Propacetamol USP/EP/BP
  • Propacatemol
  • Propacetamo
  • 66532-85-2
  • 66532-86-2