2-AMINO-3-IODO-5-NITROPYRIDINE

Product Name: 2-AMINO-3-IODO-5-NITROPYRIDINE
CAS No.: 25391-56-4
Chemical Name: 2-AMINO-3-IODO-5-NITROPYRIDINE
Synonyms: 3-iodo-5-nitro-2-pyridinamine;3-IODO-5-NITROPYRIDIN-2-AMINE;2-AMINO-3-IODO-5-NITROPYRIDINE;2-Pyridinamine, 3-iodo-5-nitro-;3-Iodo-5-nitro-pyridin-2-ylamine;2-AMINO-3-IODO-5-NITROPYRIDINE ISO 9001：2015 REACH
CBNumber: CB2782292
Molecular Formula: C5H4IN3O2
Formula Weight: 265.01
MOL File: 25391-56-4.mol

More

Less

2-AMINO-3-IODO-5-NITROPYRIDINE Property

Melting point:: 231-236 °C
Boiling point:: 391.7±42.0 °C(Predicted)
Density: 2.229±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: solid
pka: 0.41±0.49(Predicted)
Appearance: Light yellow to yellow Solid

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38-43
Safety Statements: 26-36/37
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29333990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 694738
Product name: 2-Amino-3-iodo-5-nitropyridine
Purity: 97%
Packaging: 1g
Price: $70.1
Updated: 2023/06/20

Sigma-Aldrich

Product number: 694738
Product name: 2-Amino-3-iodo-5-nitropyridine
Purity: 97%
Packaging: 5g
Price: $197
Updated: 2022/05/15

TRC

Product number: I715710
Product name: 3-Iodo-5-nitropyridin-2-amine
Packaging: 50mg
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: J50360
Product name: 2-Amino-3-iodo-5-nitropyridine
Packaging: 1g
Price: $15
Updated: 2021/12/16

Matrix Scientific

Product number: 046760
Product name: 3-Iodo-5-nitro-2-pyridinamine
Purity: >95%
Packaging: 500mg
Price: $16
Updated: 2021/12/16

More

Less

2-AMINO-3-IODO-5-NITROPYRIDINE Chemical Properties,Usage,Production

Uses

Useful starter in azaindole chemistry.

Synthesis

4214-76-0

25391-56-4

General procedure for the synthesis of 2-amino-3-iodo-5-nitropyridine from 2-amino-5-nitropyridine: 5-nitropyridin-2-amine (14 g, 100 mmol), potassium iodide (16.6 g, 100 mmol) and potassium iodate (10.7 g, 50 mmol) were dissolved in dilute sulfuric acid (2 N, 200 mL). The reaction mixture was stirred at 80 °C overnight. Upon completion of the reaction, the pH was adjusted slowly by adding sodium hydroxide solution (5 N, 80 mL) to about 10. The resulting solid product was collected by filtration, washed sequentially with deionized water and ethanol and finally dried under vacuum. The target compound 2-amino-3-iodo-5-nitropyridine (25 g, 94% yield) was obtained. The structure of the product was characterized by 1H NMR (300 MHz, DMSO-d6) and mass spectrometry (ESI): 1H NMR δ 6.80-8.40 (br s, 2H), 8.57 (d, J = 2.4 Hz, 1H), 8.84 (d, J = 2.4 Hz, 1H); MS (ESI) m/z 264 [M+H]+.

References

[1] Synthesis, 2005, # 15, p. 2503 - 2506
[2] Patent: WO2010/32, 2010, A1. Location in patent: Page/Page column 78-79
[3] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 14, p. 3853 - 3860
[4] Patent: WO2012/127506, 2012, A1. Location in patent: Page/Page column 56-57
[5] Organic Process Research and Development, 2015, vol. 19, # 9, p. 1282 - 1285

2-AMINO-3-IODO-5-NITROPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-AMINO-3-IODO-5-NITROPYRIDINE Suppliers

China 91 Germany 2 India 4 Switzerland 1 United Kingdom 4 United States 13 Global 115

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Sphinx Scientific Laboratory, LLC

Tel: --
Fax: --
Email: sales@sphinxscientificlab.com
Country: United States
ProdList: 3343
Advantage: 50

NOVASYN ORGANICS PVT LTD

Tel: --
Fax: --
Email: info@novasynorganics.com
Country: United States
ProdList: 1316
Advantage: 55

Ryan Scientific, Inc.

Tel: --
Fax: --
Email: ryan.reichlyn@ryansci.com
Country: United States
ProdList: 6439
Advantage: 60

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

Asymchem Laboratories, Inc.

Tel: --
Fax: --
Email: info@asymchem.com
Country: United States
ProdList: 1315
Advantage: 69

Milestone PharmTech LLC

Tel: --
Fax: --
Email: sales@milestonepharmtech.com
Country: United States
ProdList: 1316
Advantage: 47

More

Less

View Lastest Price from 2-AMINO-3-IODO-5-NITROPYRIDINE manufacturers

Dideu Industries Group Limited

Product: 2-AMINO-3-IODO-5-NITROPYRIDINE 25391-56-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-07

Career Henan Chemical Co

Product: 2-AMINO-3-IODO-5-NITROPYRIDINE 25391-56-4
Price: US $5.50/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1kg-100kg
Release date: 2020-01-10

25391-56-4, 2-AMINO-3-IODO-5-NITROPYRIDINERelated Search:

2-Amino-3-bromo-5-methylpyridine 3-iodo-5-(trifluoromethyl)-2-pyridinylamine 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine 2-Amino-3-bromo-5-nitropyridine METHYL 6-AMINO-5-BROMONICOTINATE 6-AMino-5-iodo-nicotinic acid Methyl ester 2-AMINO-3-IODO-5-METHYLPYRIDINE methyl 6-amino-5-chloronicotinate 3-Chloro-5-(trifluoromethyl)pyridin-2-amine 6-AMINO-5-CHLORO-NICOTINONITRILE 2-AMINO-3-CHLORO-5-NITROPYRIDINE 2-AMINO-5-IODO-3-NITROPYRIDINE 5-IODO-PYRIDIN-3-YLAMINE 2-AMINO-3-IODO-5-NITRO-6-METHYLPYRIDINE 3-Iodopyridin-2-amine 2-AMINO-3-IODO-5-NITROPYRIDINE

2-AMINO-3-IODO-5-NITROPYRIDINE

3-IODO-5-NITROPYRIDIN-2-AMINE

3-iodo-5-nitro-2-pyridinamine

3-Iodo-5-nitro-pyridin-2-ylamine

2-Pyridinamine, 3-iodo-5-nitro-

2-AMINO-3-IODO-5-NITROPYRIDINE ISO 9001：2015 REACH

25391-56-4

Heterocycle-Pyridine series

amine| alkyl Iodine| nitro-compound

Boronic Acid

Pyridine

Halides

Pyridines