Temocapril hydrochloride

Product Name: Temocapril hydrochloride
CAS No.: 110221-44-8
Chemical Name: Temocapril hydrochloride
Synonyms: CS-622;Acecol;CS-622 HCl;TemocarpileHCL;Temocapril Hcl;Carbovir Impurity 4;Temocarpilhydrochloride;TEMOCAPRIL HYDROCHLORIDE;CS-622 HCl|Temocapril HCl;Temocapril hydrochloride, >=99%
CBNumber: CB2841030
Molecular Formula: C23H28N2O5S2.ClH
Formula Weight: 513.076
MOL File: 110221-44-8.mol

More

Less

Temocapril hydrochloride Property

Melting point:: 196-2000C (dec)
alpha: 25D +47.7° (c = 1 in DMF)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White
CAS DataBase Reference: 110221-44-8(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
Toxicity: LD50 in mice, rats, dogs (mg/kg): >5000, >5000, >800 orally (Koike)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 18241
Product name: Temocapril (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 18241
Product name: Temocapril (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 18241
Product name: Temocapril (hydrochloride)
Purity: ≥98%
Packaging: 25mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 18241
Product name: Temocapril (hydrochloride)
Purity: ≥98%
Packaging: 50mg
Price: $214
Updated: 2024/03/01

TRC

Product number: T017301
Product name: TemocaprilHydrochloride
Packaging: 5mg
Price: $60
Updated: 2021/12/16

More

Less

Temocapril hydrochloride Chemical Properties,Usage,Production

Description

Temocapril is a novel ACE inhibitor marketed in Japan for the treatment of hypertension. Temocapril is three times more potent than enalapril by oral administration, and has a long duration of action. It is characterized by a rapid onset of action resulting from a fast conversion of temocapril to the active metabolite diacid. Unlike most ACE inhibitors which are excreted mainly through the kidneys, temocapril is excreted predominantly through the biliary route indicating that temocapril is especially useful for treating hypertensive patients with renal dysfunction. The potential usefulness of temocapril in the treatment of congestive heart failure has been reported.

Chemical Properties

White To Off-White Solid

Originator

Sankyo (Japan)

Uses

Angiotensin-converting enzyme (ACE) inhibitor. Hydrolyzed in vivo to the active diacid metabolite.

Uses

angiotensin-converting enzyme inhibitor (ACE-I)

Definition

ChEBI: Temocapril hydrochloride is a dipeptide.

brand name

Acecol

Temocapril hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Temocapril hydrochloride Suppliers

Canada 1 China 150 Germany 1 India 3 South Korea 1 United Kingdom 4 United States 20 Global 180

Shanghai Synteam Biochem CO.,ltd

Tel: +86-021-58380978 +86-18017016373
Fax: 021-58380978
Email: info@systeambc.com
Country: China
ProdList: 937
Advantage: 50

Hubei Kailong Biotechnology Co.,Ltd.

Tel: 19526384105
Email: 3671394075@qq.com
Country: China
ProdList: 2454
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2210
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

ForeChem (Nantong) Technology Co.,Ltd.

Tel: 513-85982855 18921614129
Fax: 051385915507
Email: sales@xianxingpharm.com
Country: China
ProdList: 1819
Advantage: 61

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9551
Advantage: 66

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2127
Advantage: 70

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 0712-0712-2580635 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
Advantage: 52

More

Less

View Lastest Price from Temocapril hydrochloride manufacturers

Hebei Duling International Trade Co. LTD

Product: Temocapril hydrochloride 110221-44-8
Price: US $25.00-18.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2023-01-06

Zhuozhou Wenxi import and Export Co., Ltd

Product: Temocapril hydrochloride 110221-44-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Temocapril hydrochloride 110221-44-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

110221-44-8, Temocapril hydrochlorideRelated Search:

Cephalothin sodium D-Glucosamine hydrochloride Methoxyammonium chloride Triethylamine hydrochloride Glycine 6-Aminocaproic acid 2-Aminophenol Tetrahydrothiophene Tris(hydroxymethyl)aminomethane Thifensulfuron Cetirizine dihydrochloride Topotecan hydrochloride Pyridine hydrochloride 1,1'-Carbonyldiimidazole Temocaprilat ALTRENOGEST 2-[(2S)-6-[[(1S)-1-Ethoxycarbonyl-3-phenyl-propyl]amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid L-Homophenylalanine ethyl ester hydrochloride

TEMOCAPRIL HYDROCHLORIDE

Temocapril HCl and intermediates

Acecol

CS-622

1,4-Thiazepine-4(5H)-acetic acid, 6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, monohydrochloride, (2S,6R)- (9CI)

1,4-Thiazepine-4(5H)-acetic acid, 6-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, monohydrochloride, [2S-[2a,6b(R*)]]-

Temocapril Hcl

TemocarpileHCL

Temocarpilhydrochloride

(2S,6R)-6-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic Acid Hydrochloride

(+)-[(2S,6R)-6-[[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-5-oxo-2-(2-thienyl)perhydro-1,4-thiazepin-4-yl]acetic acid hydrochloride

(2S,6R)-6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic acid,hydrochloride (1:1)

CS-622 HCl

Temocapril hydrochloride, >=99%

2-[(2S,6R)-6-[[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-5-oxo-2-(2-thienyl)-2,5,6,7-tetrahydro-1,4-thiazepine-4(3H)-yl]acetic acid·hydrochloride

1,4-Thiazepine-4(5H)-aceticacid,6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-,hydrochloride (1:1), (2S,6R)-

2-[6-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid hydrochloride

Temocapril hydrochloride USP/EP/BP

TIANFU-CHEM - Temocapril hydrochloride

2-((2S,6R)-6-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl)acetic acid hydrochloride

Carbovir Impurity 4

CS-622 HCl|Temocapril HCl

110221-44-8

10221-44-8

110221-48-8

C23H28N2O5S2HCl

C23H28N2O5S2xHCl

C23H29ClN2O5S2

Intermediates & Fine Chemicals

Pharmaceuticals

Inhibitors