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norfenefrine

Product Name
norfenefrine
CAS No.
536-21-0
Chemical Name
norfenefrine
Synonyms
Normetol;Normezaton;Metacardiol;Brn 1211018;norfenefrine;m-Octopamine;Metaoctopamine;DL-m-Octopamine;NORFENEFRINEBASE;Normetasympathol
CBNumber
CB2902175
Molecular Formula
C8H11NO2
Formula Weight
153.18
MOL File
536-21-0.mol
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norfenefrine Property

Melting point:
75-77 °C
Boiling point:
276.1°C (rough estimate)
Density 
1.1577 (rough estimate)
refractive index 
1.5010 (estimate)
pka
pKa 8.67(H2O,t undefined,I undefined) (Uncertain)
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Safety

Toxicity
LD50 oral in rat: 390mg/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0015836
Product name
3-(2-AMINO-1-HYDROXYETHYL)PHENOL
Purity
95.00%
Packaging
0.5G
Price
$605
Updated
2021/12/16
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norfenefrine Chemical Properties,Usage,Production

Originator

Zordel,Grelan,Japan,1970

Definition

ChEBI: Norfenefrine is a member of phenols.

Manufacturing Process

100 parts of the hydrochloride of meta-hydroxy-ω-aminoacetophenone of melting point 220°C to 222°C (obtainable by brominating metaacetoxyacetophenone, causing the bromoketone to react with sodium iodide, adding hexamethylenetetramine to the iodide in an indifferent solvent and scission of the addition product in acid solution) are shaken in aqueous solution with hydrogen in presence of 2 parts of palladium catalyst until 2 atomic proportions of hydrogen have been absorbed. The catalyst is now filtered and the filtrate evaporated in a vacuum; and the crystalline and completely dry residue is dissolved in absolute alcohol and a precipitate is produced by adding dry ether. The hydrochloride of metahydroxyphenylethanolamine thus obtained forms white crystals of melting point 159°C to 160°C.

Therapeutic Function

Adrenergic

norfenefrine Preparation Products And Raw materials

Raw materials

Preparation Products

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norfenefrine Suppliers

Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42

536-21-0, norfenefrineRelated Search:


  • norfenefrine
  • NORFENEFRINEBASE
  • (+-)-m-Octopamine
  • (+-)-Norphenylephrine
  • 1-(3-Hydroxyphenyl)-2-aminoethanol
  • 1-(m-Hydroxyphenyl)-2-aminoethanol
  • a-(Aminomethyl)-m-hydroxybenzyl alcohol
  • Benzenemethanol, a-(aminomethyl)-3-hydroxy- (9CI)
  • Benzyl alcohol, a-(aminomethyl)-m-hydroxy- (6CI, 8CI)
  • DL-1-(3-Hydroxyphenyl)-2-aminoethanol
  • dl-1-(m-Hydroxyphenyl)-2-aminoethanol
  • DL-m-Octopamine
  • DL-Norphenylephrine
  • Metacardiol
  • Metaoctopamine
  • m-Hydroxyphenylethanolamine
  • m-Octopamine
  • Normetasympathol
  • Normetasynephrine
  • Normetol
  • Normezaton
  • p-Hydroxynoradrenaline
  • rac-(R*)-2-Amino-1-(3-hydroxyphenyl)ethanol
  • 1-(3-Hydroxyphenyl)-1-hydroxy-2-aminoethane
  • 4779-94-6 (Hydrochloride)
  • alpha-(Aminomethyl)-m-hydroxybenzyl alcohol
  • Benzyl alcohol, alpha-(aminomethyl)-m-hydroxy-
  • Brn 1211018
  • Einecs 208-626-8
  • alpha-(AMinoMethyl)-3-hydroxybenzeneMethanol
  • Benzenemethanol, α-(aminomethyl)-3-hydroxy-
  • Norfenefrine Impurity A
  • Etilefrine hydrochloride EP Impurity C
  • Etilefrine EP Impurity C Acetate salt
  • 536-21-0