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Rink Amide Linker

Product Name
Rink Amide Linker
CAS No.
145069-56-3
Chemical Name
Rink Amide Linker
Synonyms
FMoc-Linker;RINK AMIDE LINKER;FMOC-RINK LINKER;DK7874;RAMAGE;Fmoc-Liner;KNORR LINKER;Rink Amide Linke;Rink AMind Linker;FMOC-AMIDE-LINKER
CBNumber
CB3104341
Molecular Formula
C32H29NO7
Formula Weight
539.58
MOL File
145069-56-3.mol
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Rink Amide Linker Property

Melting point:
~180 °C (dec.)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
BRN 
5841553
InChIKey
UPMGJEMWPQOACJ-UHFFFAOYSA-N
SMILES
C(O)(=O)COC1=CC=C(C(C2=CC=C(OC)C=C2OC)NC(OCC2C3C(=CC=CC=3)C3C2=CC=CC=3)=O)C=C1
CAS DataBase Reference
145069-56-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
22-24/25-37/39-26
WGK Germany 
3
HS Code 
29242995
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
38784
Product name
4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid
Purity
≥99.0% (HPLC)
Packaging
5g
Price
$50.8
Updated
2023/01/07
TRC
Product number
R590710
Product name
RinkAmideLinker
Packaging
2.5g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
CS-W011472
Product name
2-(4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)(2,4-dimethoxyphenyl)methyl)phenoxy)aceticacid
Packaging
25g
Price
$108
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
LIN0000011
Product name
RINK AMIDE LINKER
Purity
95.00%
Packaging
1G
Price
$115.5
Updated
2021/12/16
ApexBio Technology
Product number
A7042
Product name
RinkAmideLinker
Packaging
25g
Price
$148
Updated
2021/12/16
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Rink Amide Linker Chemical Properties,Usage,Production

Uses

Rink amide linker (CAS# 145069-56-3) is a selective aldose reductase inhibitor and a potential antidiabetic drug.

Application

Most linkers are bifunctional spacers, with one end permanently anchoring to the resin and the other end temporarily linking to the peptide. Peptides anchoring to Rink linker can be easily cleaved under acidic conditions. Since the discovery of Rink linker, it has been grafted to a variety of resins and widely used for scientific investigations and industrial solid-phase peptide synthesis. Thus, Rink Amide Linker is the key reagent to prepare this series of Rink-resins[1].

Origin

Rink Amide Linker was first designed by Rink and further developed by Bernatowicz and co-workers for the preparation of peptide C-terminal amides[1]. Rink Amide Linker is also known as commercial Knorr linker.

References

[1] Qin L, et al. An improved and practical synthesis of Fmoc Rink linker. Journal of Chemical Research, 2019.

Rink Amide Linker Preparation Products And Raw materials

Raw materials

Preparation Products

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Rink Amide Linker Suppliers

China 189 Europe 2 Germany 6 India 5 Japan 3 Switzerland 3 United Kingdom 9 United States 29 Global 246
Molekula Ltd
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United Kingdom
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Leancare Ltd.
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MOLEKULA Ltd.
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kevinbanks@molekula.com
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CARBONE SCIENTIFIC CO.,LTD
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ETA SCIENTIFIC Co.,Ltd
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UK GREEN SCIENTIFIC CO.,LIMITED
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Fluorochem Ltd
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Fluorochem Ltd.
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VWR International
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View Lastest Price from Rink Amide Linker manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc -Rink Linker 145069-56-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2023-09-27
Hebei Dangtong Import and export Co LTD
Product
Rink Amide Linker 145069-56-3
Price
US $100.00-80.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
200Tons
Release date
2023-11-16
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid 145069-56-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

145069-56-3, Rink Amide LinkerRelated Search:

Fmoc-Phe-OH Fmoc-Asp(OtBu)-OH Fmoc-Lys(Boc)-OH Dimethyldimethoxysilane Fomesafen RINK AMIDE RESIN 4-Dimethylaminopyridine N-(9-Fluorenylmethoxycarbonyloxy)succinimide 4-Dimethylaminobenzaldehyde Dimethoxymethane Phenyltriethoxysilane Glycine 9-Fluorenylmethyl chloroformate 6-Aminocaproic acid 3,4'-DIAMINODIPHENYLMETHANE L-Fmoc-Aspartic acid alpha-tert-butyl ester 2-Dimethylaminoethanol FMOC-RINK AMIDE-LINKER

  • Rink AMid Linker, (FoMc-AM, Knorr linker)
  • Rink AMind Linker
  • Rink Amide Linke
  • FMOC-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)-BENZHYDRYLAMINE
  • 4-[(2,4-DiMethoxyphenyl)(FMoc-aMino)Methyl]phenoxyacetic acid, 98+%
  • RINK AMIDE REAGENT
  • RINK AMIDE LINKER
  • N-FMOC-(2,4-DIMETHOXYPHENYL)AMINOMETHYL PHENOXY ACETIC ACID
  • P-[(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL]-PHENOXYACETIC ACID
  • P-((R,S)-ALPHA-[1-(9H-FLUOREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL)-PHENOXYACETIC ACID
  • P-((R,S)-ALPHA-[1-(9H-FLOUREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL)-PHENOXYACETIC ACID
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)-BENZHYDRYLAMINE
  • 4-(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC-ACID
  • 4'-[(R,S)-ALPHA-[1-(9-FLUORENYL)METHOXYCARBONYLAMINO]-2,4-DIMETHOXYBENZYL]-PHENOXYACETIC ACID
  • 4'-[(R,S)-ALPHA-[1-(9-FLUORENYL)METHOXYCARBONYLAMINO]-2,4-DIMETHOXYBENZYL]-PHENOL
  • 4-[(R,S)-ALPHA-1-(9H-FLUREN-9-YL)-METHOXY FORMAMIDO]-2,4-DIMETHOXYBENZYLPHENOXYACETIC ACID
  • 4-[(R,S)-ALPHA-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC ACID
  • 4-(2',4'-DIMETHOXYPHENYL)-FMOC-AMINOMETHYL-PHENOXYACETIC ACID
  • 4-[(2,4-DIMETHOXYPHENYL)(FMOC-AMINO)METHYL]PHENOXYACETIC ACID
  • FMOC-AMIDE-LINKER
  • FMOC-RINK LINKER
  • FMOC-RINK AMIDE-LINKER
  • FMOC RINK ACETIC ACID LINKER
  • FMOC-NH-SAL RESIN LINKER
  • KNORR LINKER
  • Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(Fmoc Amino)Methyl)Phenoxyacetic Acid 145069-56-3 C32h29no7
  • Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(Fmoc Amino)Methyl)Phenoxyacetic Acid
  • Fmoc-Liner
  • Fmoc-Linker(4-[(2,4-Dimethoxyphenyl)(Fmoc-Amino)Methyl]-PhenoxyaceticAcid)
  • 4-[(2,4-dimethoxyphenyl)(fmoc-amino)me] phenoxy acetic acid
  • 4-[(2,4-DIMETHOXYPHENYL)(FMOC-AMINO)METHYL]PHENOXYACETIC ACID[RINK AMIDE LINKER]
  • 4-[(2,4-DIMETHOXYPHENYL) (FMOC-AMINO) METHYL] PHENOXYACETIC ACID RINK AMIDE LINKER 98.5%
  • RINK AMIDE LINKER:KNORR LINKER:4-[(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC ACID
  • Knorr-Linker, 4-{(R,S)-alpha-[1-(9-Fluorenyl)methoxycarbonylamino]-2,4-dimethoxybenzyl}-phenoxyacetic acid
  • RINK AMIDE LINKER, 98.5% MIN.
  • 4-[(R,S)--[1-(9H-Fluoren-9-yl)-methoxyformamido]-2,4-dimethoxybenzylphenoxyacetic acid
  • 4-[(R,S)-a-[1-(9H-Fluoren-9-yl)-methoxy-formamido]-2
  • 2-(4-((((9H-fluoren-9-yl)methoxy)carbonylamino)(2,4-dimethoxyphenyl)methyl)phenoxy)acetic acid
  • 4-[(R,S)-a-[1-(9H-Fluoren-9-yl)-methoxy-formamido]
  • FMoc-Linker
  • 2-{4-[(2,4-diMethoxyphenyl)({[(9H-fluoren-9-ylMethoxy)carbonyl]aMino})Methyl]phenoxy}acetic acid
  • Fmoc-Knorr-Linker: Fmoc-Rink Amide Linker (2), 4′-{(R,S)-alpha-[1-(9-Fluorenyl)methoxycarbonylamino]-2,4-dimethoxybenzyl}-phenoxyacetic acid
  • Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(FMOC amino)methyl)ph
  • 2-[4-[(2,4-dimethoxyphenyl)-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]methyl]phenoxy]acetic acid
  • Rink Amide Linker, 99% min.
  • 4-[(2,4-Dimethoxyphenyl)(Fmoc-Amino)Methyl]PhenoxyaceticAci
  • 4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid USP/EP/BP
  • DK7874
  • Rink Amide Linker Resin (Knorr Linker) extrapure, 99%
  • RAMAGE
  • 145069-56-3
  • 145068-56-3
  • C32H28NO7
  • C32H29NO7
  • Bifunctional Crosslinkers
  • Linkers
  • Peptide Synthesis
  • Specialty Synthesis