Betaxolol hydrochloride

Product Name: Betaxolol hydrochloride
CAS No.: 63659-19-8
Chemical Name: Betaxolol hydrochloride
Synonyms: Kerlon;kerlone;SL 75212;betoptic;sl-d.212;Betaxolo;Betoptima;sl75212-10;SL 75212 HCl;Betaxolol HC
CBNumber: CB3153329
Molecular Formula: C18H30ClNO3
Formula Weight: 343.89
MOL File: 63659-19-8.mol

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Betaxolol hydrochloride Property

Melting point:: 116°
storage temp.: 2-8°C
solubility: H₂O: 36 mg/mL, soluble
form: solid
color: white
Water Solubility: Soluble to 50 mM in water
Merck: 14,1182
Stability:: Hygroscopic
InChI: InChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H
InChIKey: CHDPSNLJFOQTRK-UHFFFAOYSA-N
SMILES: C1(OCC(O)CNC(C)C)C=CC(CCOCC2CC2)=CC=1.Cl
CAS DataBase Reference: 63659-19-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
RTECS: UA9823000
HS Code: 2922504500
Toxicity: LD50 in mice (mg/kg): 944 orally; 37 i.v. (Manoury)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0001360
Product name: Betaxolol for peak identification
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 15 mg
Price: $118
Updated: 2025/07/31

Sigma-Aldrich

Product number: B5683
Product name: Betaxolol hydrochloride
Purity: >98% (HPLC)
Packaging: 10mg
Price: $137.2
Updated: 2025/07/31

Sigma-Aldrich

Product number: BP686
Product name: Betaxolol hydrochloride
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 100 mg
Price: $234
Updated: 2025/07/31

Sigma-Aldrich

Product number: B1103000
Product name: Betaxolol hydrochloride
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 60 mg
Price: $153
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1069903
Product name: Betaxolol hydrochloride
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $425
Updated: 2025/07/31

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Betaxolol hydrochloride Chemical Properties,Usage,Production

Description

Betaxolol (hydrochloride) (Item No. 26285) is an analytical reference standard categorized as a β₁-adrenergic receptor antagonist. Formulations containing β-adrenergic receptor antagonists have been used to enhance physical performance in athletes. This product is intended for use in analytical forensic applications. This product is also available as a general research tool .

Description

Betaxolol hydrochloride is a cardioselective β-adrenergic blocker, reportedly devoid of intrinsic sympathomimetic and membrane stabilizing properties. Its long duration of action permits once-daily dosing in mild to moderate hypertension. It is also being evaluated in glaucoma.

Chemical Properties

White or almost white, crystalline powder.

Originator

Synthelabo (France)

Uses

antifungal

Uses

Betaxolol Hydrochloride, a cardioselective β1-adrenergic blocker. An antihypertensive; antiglaucoma.

Definition

ChEBI: The hydrochloride salt of betaxolol.

brand name

Betoptic (Alcon); Kerlone (Sanofi Aventis).

Biological Activity

Selective β 1 -adrenoceptor antagonist.

storage

Store at RT

References

[1] SEUNG-WOON MYUNG Cheon H J. Gas chromatograph–mass spectrometric method for the determination of carvedilol and its metabolites in human urine[J]. Journal of Chromatography B, 2005, 822 1: Pages 70-77. DOI: 10.1016/j.jchromb.2005.05.023
[2] PANKAJ GUPTA R G. Amino Functionalized Graphene Oxide and Polymer Nanocomposite Based Electrochemical Platform for Sensitive Assay of Anti-Doping Drug Atenolol in Biological Fluids[J]. Journal of The Electrochemical Society, 2016, 163 1. DOI: 10.1149/2.0281613jes
[3] A WELLSTEIN G G B D Palm. Affinity and selectivity of beta-adrenoceptor antagonists in vitro.[J]. Journal of Cardiovascular Pharmacology, 1986, 8 Suppl 11: S36-40. DOI: 10.1097/00005344-198511001-00006
[4] DOROTA POZAROWSKA Zbigniew D Piotr Pozarowski. Cytometric assessment of cytostatic and cytotoxic effects of topical glaucoma medications on human epithelial corneal line cells?[J]. Cytometry Part B: Clinical Cytometry, 2009, 78B 2: 130-137. DOI: 10.1002/cyto.b.20493
[5] N. SHARIF. Levobetaxolol (Betaxon) and other beta-adrenergic antagonists: preclinical pharmacology, IOP-lowering activity and sites of action in human eyes.[J]. Journal of Ocular Pharmacology and Therapeutics, 2001, 26 1: 305-317. DOI: 10.1089/108076801753162726
[6] GLYN CHIDLOW Neville N O José Melena. Betaxolol, a β1-adrenoceptor antagonist, reduces Na+ influx into cortical synaptosomes by direct interaction with Na+ channels: comparison with other β-adrenoceptor antagonists[J]. British Journal of Pharmacology, 2009, 130 4: 759-766. DOI: 10.1038/sj.bjp.0703369

Betaxolol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Betaxolol hydrochloride Suppliers

Americas 1 Belgium 1 China 180 Europe 1 France 3 Germany 8 India 26 Italy 5 Japan 3 Nepal 1 Poland 1 South Korea 2 Spain 2 Switzerland 1 United Kingdom 7 United States 34 Venezuela 1 Global 277

Anhui Qingyun Pharm & Chem CO.,Ltd

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BioBioPha Co., Ltd.

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View Lastest Price from Betaxolol hydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Betaxolol hydrochloride 63659-19-8
Price: US $0.00/Kg/Bag
Min. Order: 1KG
Purity: 99%min
Supply Ability: 500KGS
Release date: 2021-09-13

Hebei Chuanghai Biotechnology Co,.LTD

Product: Betaxolo hydrochloride 63659-19-8
Price: US $1.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 ton
Release date: 2024-08-20

Hebei Zhanyao Biotechnology Co. Ltd

Product: Betaxolol hydrochloride 63659-19-8
Price: US $10.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2021-11-17

63659-19-8, Betaxolol hydrochlorideRelated Search:

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1-[4-[2-(CYCLOPROPYLMETHOXY)ETHYL]PHENOXY]-3-ISOPROPYLAMINO-2-PROPANOL HYDROCHLORIDE

BETAXOLOL CHLOROHYDRATE

BETAXOLOL HCL

BETAXOLOL HYDROCHLORIDE

BETAXOLOL HYDROCHLORIDE MONOHYDRATE

SL 75212

(+-)-1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-(isopropylamino)-2-propano

1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-isopropylaminopropan-2-olhydroc

Betaxolol for peak identification

BETAXALOL HYDROCHLORIDE

1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol,hydrochloride (1:1)

SL 75212 HCl

1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)-2-propanol hydrate hydrochloride

betoptic

kerlone

sl75212-10

sl-d.212

1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride

Betaxolo

2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride

Betoptima

(R)-Betaxolol-d7 Hydrochloride

βxolol hydrochloride

(±)-Betaxolol-d7 HCl

1-(4-(2-(Cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol hydrochloride

Kerlon

Betaxolol Hydrochloride (200 mg)

Betaxolol hydrochloride CRS

Betaxolol for peak identification CRS

Betaxolol hydrochloride USP/EP/BP

Betaxolol hydrochloride salt

Betaxolol hydrochlor

Betaxolol HCl (SL75212)

1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy...

Betaxolol HClQ: What is Betaxolol HCl Q: What is the CAS Number of Betaxolol HCl Q: What is the storage condition of Betaxolol HCl Q: What are the applications of Betaxolol HCl

Betaxolol Hydrochloride (1069903)

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Betaxolol HCl - Bio-X ?

Betaxolol hydrochloride 98~102%

63659-19-8

633659-19-8

63959-19-8

C18H29NO3HClH2O

C18H29NO3HCl

Cardiovascular

Adrenoceptor