ChemicalBook > CAS DataBase List > Ethyl L-alaninate hydrochloride

Ethyl L-alaninate hydrochloride

Product Name
Ethyl L-alaninate hydrochloride
CAS No.
1115-59-9
Chemical Name
Ethyl L-alaninate hydrochloride
Synonyms
L-ALANINE ETHYL ESTER HYDROCHLORIDE;ethyl alaninate hydrochloride;CADR-013;H-ALA-OET HCL;L-Ala-OEt.HCL;ALANINE-OET HCL;H-L-Ala-OEt*HCl;Ethyl L-alaninate hy;L-Alanine ethyl este;Tenofovir Impurity 79
CBNumber
CB3164086
Molecular Formula
C5H12ClNO2
Formula Weight
153.61
MOL File
1115-59-9.mol
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Ethyl L-alaninate hydrochloride Property

Melting point:
78-80 °C (dec.)(lit.)
alpha 
3.1 º (c=2.5, H2O)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
100g/l
form 
Solid
color 
White to Off-White
optical activity
[α]22/D +2.5°, c = 2.5 in H2O
Sensitive 
Hygroscopic
BRN 
3594395
InChI
InChI=1/C5H11NO2.ClH/c1-3-8-5(7)4(2)6;/h4H,3,6H2,1-2H3;1H/t4-;/s3
InChIKey
JCXLZWMDXJFOOI-NDILARRWNA-N
SMILES
C(=O)([C@@H](N)C)OCC.Cl |&1:2,r|
CAS DataBase Reference
1115-59-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
F 
3-10
Hazard Note 
Irritant
HS Code 
29224995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
855669
Product name
L-Alanine ethyl ester hydrochloride
Purity
99%
Packaging
5g
Price
$51.3
Updated
2025/07/31
Sigma-Aldrich
Product number
855669
Product name
L-Alanine ethyl ester hydrochloride
Purity
99%
Packaging
25g
Price
$176
Updated
2025/07/31
TCI Chemical
Product number
A2494
Product name
L-Alanine Ethyl Ester Hydrochloride
Purity
>98.0%(N)
Packaging
5g
Price
$25
Updated
2025/07/31
TCI Chemical
Product number
A2494
Product name
L-Alanine Ethyl Ester Hydrochloride
Purity
>98.0%(N)
Packaging
25g
Price
$87
Updated
2025/07/31
TRC
Product number
A510580
Product name
L-Alanine ethyl ester hydrochloride
Packaging
10g
Price
$135
Updated
2021/12/16
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Ethyl L-alaninate hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white to off-white adhering crystalline powder

Uses

L-Alanine Ethyl Ester Hydrochloride is used in the synthesis of nucleoside phosphoramidates as antiviral agents for human immunodeficiency and hepatitis B viruses. Also used in synthesis of enantiomerically pure amino acid ester isocyanates.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

64-17-5

56-41-7

1115-59-9

L-alanine (3.56 g, 0.04 mol) was dissolved in ethanol (30 mL) at -5 °C and thionyl chloride (3.6 mL) was added slowly and dropwise, keeping stirring. Subsequently, the reaction mixture was warmed up to 78 °C and the reaction was refluxed in ethanol for 1.5 hours. Upon completion of the reaction, the solvent was removed by vacuum distillation to afford L-alanine ethyl ester hydrochloride (2a) in over 80% yield. The physical constants of the product 2a were in agreement with the data reported in literature [24].

References

[1] Chemical Communications, 2011, vol. 47, # 26, p. 7347 - 7349
[2] Dalton Transactions, 2015, vol. 44, # 3, p. 1170 - 1177
[3] Tetrahedron, 1999, vol. 55, # 11, p. 3337 - 3354
[4] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006, vol. 45, # 8, p. 1942 - 1944
[5] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1994, # 7, p. 1455 - 1462

Ethyl L-alaninate hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ethyl L-alaninate hydrochloride manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Ethyl L-alaninate hydrochloride 1115-59-9
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-04
Henan Aochuang Chemical Co.,Ltd.
Product
Ethyl L-alaninate hydrochloride 1115-59-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-28
Wuhan Boyuan Import & Export Co., LTD
Product
Ethyl L-alaninate hydrochloride, L-Alanine ethyl ester hydrochloride CAS NO.1115-59-9 1115-59-9
Price
US $1.00/G
Min. Order
100G
Purity
99.9%
Supply Ability
50000 tons
Release date
2018-10-25

1115-59-9, Ethyl L-alaninate hydrochlorideRelated Search:

EC 2.6.1.2 Phenprobamate Topotecan hydrochloride 2-Ethoxyethanol Ethylparaben Glycine ethyl ester hydrochloride L-Alanine Tris(trimethylsilyl)phosphate ISOXADIFEN-ETHYL Trinexapac-ethyl D-Alanine L-Alanine methyl ester hydrochloride Ethanol Ethyl acetate Diethyl L-glutamate hydrochloride rac-Tenofovir-d7 Chloromethyl isopropyl carbonate ChloroMethyl Propyl Carbonate

  • Ethyl L-alaninate hydrochloride
  • H-ALA-OET HCL
  • H-ALA-OET HYDROCHLORIDE
  • L-ALANINE ETHYL ESTER HCL
  • L-ALANINE ETHYL ESTER HYDROCHLORIDE
  • L-ETHYL 2-AMINOPROPANOATE HYDROCHLORIDE
  • L-ETHYL ALANATE HYDROCHLORIDE
  • L-A-ALANINE, ETHYL ESTER HYDROCHLORIDE
  • ethyl alaninate hydrochloride
  • ALANINE ETHYL ESTER HCL
  • ALANINE-OET HCL
  • L-ALANINE ETHYL ESTER HCI
  • H-L-Ala-OEt*HCl
  • L-Alanine ethyl ester hydrochloride, 98+%
  • Ethyl (2S)-2-aminopropanoate hydrochloride
  • Alanine ethyl·hydrochloride
  • L-Ala-OEt.HCL
  • Ethyl L-alaninate hy
  • L-Alanine ethyl este
  • L-Alanine ethlester hydrochloride
  • (S)-Ethyl 2-aMinopropanoate hydrochloride
  • L-Alanine ethyl ester hydrochloride 99%
  • Ethyl L-Alaninate Hydrochloride,99%e.e.
  • L-Ethyl alanate hydrochloride for synthesis
  • Ethyl L-alaninate hydrochloride, L-Alanine ethyl ester hydrochloride CAS NO.1115-59-9
  • CADR-013
  • Tenofovir Impurity 79
  • Tenofovir Impurity 46 HCl
  • L-Alanine, ethyl ester,hydrochloride (1:1)
  • [(2S)-1-ethoxy-1-oxopropan-2-yl]ammonium
  • Tenofovir disoproxil Impurity 28
  • L-Alanine ethyl ester hydrochloride, 98.5%
  • L-Alanine Ethyl Ester Hydrochloride &gt
  • (S)-2-Aminopropionic Acid Ethyl Ester Hydrochloride
  • Ethyl (S)-2-Aminopropionate Hydrochloride
  • Ethyl L-alaninate hydrochloride USP/EP/BP
  • L-Alaninate Ethyl hydrochloride
  • Tenofovir Impurity 5 HCl
  • Ethyl (S)-2-amino-propanoate HCl
  • (R)-bis(4-bromophenyl) (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
  • <sc>L</sc>-Alanine ethyl ester hydrochloride
  • 1115-59-9
  • 90890-21-7
  • 1115-59-5
  • 115-59-9
  • AMINE
  • Peptide Synthesis
  • Specialty Synthesis
  • Alanine
  • Amino Acid Derivatives
  • amino
  • Alanine [Ala, A]
  • Amino Acids and Derivatives
  • Amino Acids
  • Amino hydrochloride
  • Alanine
  • Amino Acid Derivatives
  • Peptide Synthesis