BIOTIN HYDRAZIDE

Product Name: BIOTIN HYDRAZIDE
CAS No.: 66640-86-6
Chemical Name: BIOTIN HYDRAZIDE
Synonyms: Biotin-Hz;Biotin-NHNH2;CAS_66640-86-6;5-((3aS,4S,6aR);BIOTIN-Hydrazid;BIOTIN-HYDRAZIDE;BIOTIN HYDRAZIDE;Biontin-Hydrazide;Biotin Impurity 32;Biotinyl hydrazine
CBNumber: CB3175354
Molecular Formula: C10H18N4O2S
Formula Weight: 258.34
MOL File: 66640-86-6.mol

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BIOTIN HYDRAZIDE Property

Melting point:: 245-247 °C
Boiling point:: 633.1±40.0 °C(Predicted)
Density: 1.243±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: ≤20 mg/mL
form: powder
pka: 13.25±0.35(Predicted)
color: White to Almost white
BRN: 28347
InChIKey: KOZWHQPRAOJMBN-ZKWXMUAHSA-N
CAS DataBase Reference: 66640-86-6(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
F: 10
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B7639
Product name: (+)-Biotin hydrazide
Purity: ≥97% (TLC), powder
Packaging: 100mg
Price: $102
Updated: 2024/03/01

Sigma-Aldrich

Product number: B7639
Product name: (+)-Biotin hydrazide
Purity: ≥97% (TLC), powder
Packaging: 1g
Price: $520
Updated: 2024/03/01

TCI Chemical

Product number: B2431
Product name: Biotin Hydrazide
Purity: >98.0%(HPLC)
Packaging: 25mg
Price: $32
Updated: 2024/03/01

TCI Chemical

Product number: B2431
Product name: Biotin Hydrazide
Purity: >98.0%(HPLC)
Packaging: 100mg
Price: $89
Updated: 2024/03/01

Cayman Chemical

Product number: 18418
Product name: Biotin hydrazide
Purity: ≥95%
Packaging: 100mg
Price: $57
Updated: 2024/03/01

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BIOTIN HYDRAZIDE Chemical Properties,Usage,Production

Description

Biotin hydrazide is a biotinyl derivative used to label surface functional groups, antibodies, lectins, sugars, nucleic acids, or molecules with free carboxylic or keto groups. Biotin hydrazide is used as a probe for determining protein carbonylation, an irreversible posttranslational modification resulting from the actions of reactive oxygen species or lipid oxidation products. The reaction of this probe is direct and does not require catalysts or reducing agents.

Chemical Properties

3.6

Uses

Biotin Hydrazide is a carbohydrate reactive biotinylation reagent used predominately for labeling monoclonal antibodies, unpaired cytosine residues in nucleic acids and glycoproteins.

Uses

aldehyde reactive biotinylation reagent

Uses

(+)-Biotin hydrazide has been used:

the modification of alginate
for the labelling of mitochondrial proteins from non-muscle tissues
as a component of glycoprotein staining solution
in periodic acid-biotin-hydrazide (PABH) assay for mucins
for labeling surface functional groups, biologically active molecules such as antibodies, lectins, sugars, nucleic acids or molecules with free carboxylic or keto groups.
for coupling to glycoproteins through the carbohydrate by hydrazone formation

General Description

Biotin hydrazide is a biotinylation reagent used to biotinylate glycoproteins with their sugar moieties. Biotin hydrazide can be used to prepare biotin-conjugated alginate. It can also be used for covalent attachment to PAAc via carbodi-imide cross linking.

Purification Methods

Wash the hydrazide with H2O, dry it, wash it with MeOH then Et2O, and dry. Recrystallise it from hot H2O (clusters of prisms) [Hofmann et al. J Biol Chem 144 513 1942]. [Beilstein 27 III/IV 7980.]

BIOTIN HYDRAZIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from BIOTIN HYDRAZIDE manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Biotin hydrazide HCl 66640-86-6
Price: US $0.00/g
Min. Order: 5g
Purity: >95.00%
Supply Ability: 5g
Release date: 2024-03-30

Zhuozhou Wenxi import and Export Co., Ltd

Product: BIOTIN HYDRAZIDE 66640-86-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: BIOTIN HYDRAZIDE 66640-86-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

66640-86-6, BIOTIN HYDRAZIDERelated Search:

Biotin-PEG7-Amine DANSYL HYDRAZINE Sulfo-NHS-Biotin biotinylamidoethylacetamide N-BIOTINYL-N'-MALEIMIDO-ETHYLENEDIAMINE BIOTIN-XX-NHS D-BIOTIN P-NITROPHENYL ESTER D-Biotin (+)-BIOTIN-EPSILON-AMINOCAPROIC ACID Succinimidyl 6-(biotinamido)hexanoate BIOTIN-NHS Biotin-PEG6-t-butyl ester Biotin-PEG3-alcohol DBCO-S-S-PEG3-Biotin Biotin-PEG2-iodide 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-[2-(2-hydroxyethoxy)ethyl]-2-oxo-, (3aS,4S,6aR)- Biotin-PEG6-azide Biotin-PEG4-Amide-C6-Azide

BIOTIN (LONG ARM) HYDRAZIDE

(+)-BIOTIN HYDRAZIDE

BIOTIN HYDRAZIDE

1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazid e, (3aS,4S,6aR)-

BIOTIN-HYDRAZIDE

Biotin-NHNH2

D-Biotin Hydrazide

1H-Thieno(3,4-D)imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazide, (3as-(3aalpha,4beta,6aalpha))-

Biotin-Hz

5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]iMidazol-4-yl)pentanehydrazide

Biontin-Hydrazide

Biotin hydrazide *CAS 66640-86-6*

Biotin hydrazide (5-((3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanehydrazide)

-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)

5-((3aS,4S,6aR)

Biotin hydrazide HCl

BIOTIN-Hydrazid

CAS_66640-86-6

Biotin Hydrazide &gt

Biotin Impurity 32

Biotinyl hydrazine

(+)-Biotin-hydrazide

5-[(3aR,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanehydrazide

1H-Pyrazole,3,5-bis(4-chlorophenyl)-4,8-dihydro-

5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanehydrazide

Biotin Hydrazide, 10 mM in DMSO

66640-86-6

666640-86-6

C10H18N4O2S

C10H18N4SO2

Antibody Modification

Antibody Labeling

Antibodies

BioChemical

Labeling with Biotin

Supplementary Products

Biotinylation Reagents

biotinyl

BiotinylationReagents

Biotin Labeling ReagentsGlycobiology

Detection of Biotin Labeled Glycoproteins on Western BlotsAntibody Modification

Labeling with Biotin

Antibody Labeling

Biotin/Avidin

Glycoprotein Detection

Supplementary Products