Colestipol hydrochloride

Product Name: Colestipol hydrochloride
CAS No.: 37296-80-3
Chemical Name: Colestipol hydrochloride
Synonyms: lestid;colestid;cholestabyl;COLESTIPOL HCL;COLESTIPOL HYDROCHLORIDE;Colestipol Hydrochloride (200 mg);Colestipol Hydrochloride (1146505);n'-(2-aminoethyl)-n-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine 2-(chloromethyl)oxirane hydrochloride;N-(2-AMINOETHYL)-N'-[2-[(2-AMINOETHYL)AMINO]ETHYL]-1,2-ETHANEDIAMINE POLYMER WITH (CHLOROMETHYL)OXIRANE HYDROCHLORIDE
CBNumber: CB3182169
Molecular Formula: C8H24ClN5
Formula Weight: 225.76266
MOL File: 37296-80-3.mol

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Colestipol hydrochloride Property

storage temp.: Room Temperature, under inert atmosphere
form: Solid
color: Off-White to Pale Yellow

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Safety

WGK Germany: 3
HS Code: 3914006000
Toxicity: LD50 in rats (mg/kg): >4000 i.p.; >1000 orally (Webster, Bollert)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1146505
Product name: Colestipol hydrochloride
Packaging: 200mg
Price: $454
Updated: 2024/03/01

TRC

Product number: C640093
Product name: Colestipol hydrochloride
Packaging: 2mg
Price: $50
Updated: 2021/12/16

TRC

Product number: C640093
Product name: Colestipol hydrochloride
Packaging: 20mg
Price: $85
Updated: 2021/12/16

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Colestipol hydrochloride Chemical Properties,Usage,Production

Uses

Antihyperlipidemic.

Uses

Colestipol Hydrochloride was useful for studying pharmacokinetics with Teriflunomide (A771726).

Definition

ChEBI: The hydrochloride of colestipol, a highly cross-linked, high molecular weight copolymer of diethylenetriamine and epichlorohydrin (hydrochloride), with approximately 1 out of 5 amine nitrogens protonated. It is used for binding bile acids in the intestine, inhibiting their reabsorption.

brand name

Colestid (Pharmacia & Upjohn).

General Description

Colestipol (Colestid) is ahigh–molecular-weight, insoluble, granular copolymer oftetraethylenepentamine and epichlorohydrin. It functions asan anion-exchange, resin-sequestering agent in a manner similarto that of cholestyramine resin. Colestipol hydrochloridereduces cholesterol levels without affecting triglycerides andseems to be especially effective in the treatment of type IIhyperlipoproteinemias.

Drug interactions

Potentially hazardous interactions with other drugs
Anticoagulants: may enhance or reduce effects of coumarins and phenindione.
Ciclosporin: no reports of an interaction; however, ciclosporin levels should be carefully monitored if colestipol and ciclosporin are prescribed concurrently, as colestipol may interfere with ciclosporin absorption.

Metabolism

Not applicable as colestipol is not systemically absorbed.

Colestipol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Colestipol hydrochloride Suppliers

China 17 India 9 United Kingdom 1 United States 5 Global 32

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973186 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 18338
Advantage: 68

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15352
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49374
Advantage: 58

Hubei Enxing Biotechnology Co., Ltd

Tel: 16621771607
Email: exbio_tech@163.com
Country: China
ProdList: 8210
Advantage: 58

Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd

Tel: 18162595016; 18162595016
Email: 3287908757@qq.com
Country: China
ProdList: 9122
Advantage: 58

Pushan Industry (Shaanxi) Co., Ltd

Tel: 029-81310890 18165209495
Email: 2929288192@qq.com
Country: China
ProdList: 9948
Advantage: 58

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Colestipol Hydrochloride (200 mg)

COLESTIPOL HCL

COLESTIPOL HYDROCHLORIDE

N-(2-AMINOETHYL)-N'-[2-[(2-AMINOETHYL)AMINO]ETHYL]-1,2-ETHANEDIAMINE POLYMER WITH (CHLOROMETHYL)OXIRANE HYDROCHLORIDE

n'-(2-aminoethyl)-n-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine 2-(chloromethyl)oxirane hydrochloride

cholestabyl

colestid

lestid

Colestipol Hydrochloride (1146505)

37296-80-3

3729-80-3

C11H28ClN5OHCl