Colestipol hydrochloride
- Product Name
- Colestipol hydrochloride
- CAS No.
- 37296-80-3
- Chemical Name
- Colestipol hydrochloride
- Synonyms
- lestid;colestid;cholestabyl;COLESTIPOL HCL;COLESTIPOL HYDROCHLORIDE;Colestipol Hydrochloride (200 mg);Colestipol Hydrochloride (1146505);n'-(2-aminoethyl)-n-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine 2-(chloromethyl)oxirane hydrochloride;N-(2-AMINOETHYL)-N'-[2-[(2-AMINOETHYL)AMINO]ETHYL]-1,2-ETHANEDIAMINE POLYMER WITH (CHLOROMETHYL)OXIRANE HYDROCHLORIDE
- CBNumber
- CB3182169
- Molecular Formula
- C8H24ClN5
- Formula Weight
- 225.76266
- MOL File
- 37296-80-3.mol
Colestipol hydrochloride Property
- storage temp.
- Room Temperature, under inert atmosphere
- form
- Solid
- color
- Off-White to Pale Yellow
Safety
- WGK Germany
- 3
- HS Code
- 3914006000
- Toxicity
- LD50 in rats (mg/kg): >4000 i.p.; >1000 orally (Webster, Bollert)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 1146505
- Product name
- Colestipol hydrochloride
- Packaging
- 200mg
- Price
- $454
- Updated
- 2024/03/01
- Product number
- C640093
- Product name
- Colestipol hydrochloride
- Packaging
- 2mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- C640093
- Product name
- Colestipol hydrochloride
- Packaging
- 20mg
- Price
- $85
- Updated
- 2021/12/16
Colestipol hydrochloride Chemical Properties,Usage,Production
Uses
Antihyperlipidemic.
Uses
Colestipol Hydrochloride was useful for studying pharmacokinetics with Teriflunomide (A771726).
Definition
ChEBI: The hydrochloride of colestipol, a highly cross-linked, high molecular weight copolymer of diethylenetriamine and epichlorohydrin (hydrochloride), with approximately 1 out of 5 amine nitrogens protonated. It is used for binding bile acids in the intestine, inhibiting their reabsorption.
brand name
Colestid (Pharmacia & Upjohn).
General Description
Colestipol (Colestid) is ahigh–molecular-weight, insoluble, granular copolymer oftetraethylenepentamine and epichlorohydrin. It functions asan anion-exchange, resin-sequestering agent in a manner similarto that of cholestyramine resin. Colestipol hydrochloridereduces cholesterol levels without affecting triglycerides andseems to be especially effective in the treatment of type IIhyperlipoproteinemias.
Drug interactions
Potentially hazardous interactions with other drugs
Anticoagulants: may enhance or reduce effects of
coumarins and phenindione.
Ciclosporin: no reports of an interaction; however,
ciclosporin levels should be carefully monitored if
colestipol and ciclosporin are prescribed concurrently,
as colestipol may interfere with ciclosporin
absorption.
Metabolism
Not applicable as colestipol is not systemically absorbed.
Colestipol hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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