4-Cholesten-3-one

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4-Cholesten-3-one

Product Name: 4-Cholesten-3-one
CAS No.: 601-57-0
Chemical Name: 4-Cholesten-3-one
Synonyms: CHOLESTENONE;4-Cholestenone;4-CHOLESTEN-3-ONE;3-Oxocholest-4-ene;3-OXO-4-CHOLESTENE;cholest-4-en-3-one;4-Cholestene-3-one;CHOLEST-4-ENE-3-ONE;3-KETO-4-CHOLESTENE;(+)-4-CHOLESTEN-3-ONE
CBNumber: CB3222827
Molecular Formula: C27H44O
Formula Weight: 384.64
MOL File: 601-57-0.mol

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4-Cholesten-3-one Property

Melting point:: 79-82 °C
alpha: 92.5 º (c=2, CHCl3)
Boiling point:: 451.27°C (rough estimate)
Density: 0.9717 (rough estimate)
refractive index: 1.5100 (estimate)
storage temp.: -20°C
solubility: Chloroform (Sparingly), Methanol (Slightly, Heated)
form: Solid
color: White to Off-White
optical activity: [α]23/D +91.0°, c = 2 in chloroform
Water Solubility: <0.5 g/L
BRN: 4707774
Stability:: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference: 601-57-0(CAS DataBase Reference)
NIST Chemistry Reference: Cholest-4-en-3-one(601-57-0)
EPA Substance Registry System: Cholest-4-en-3-one (601-57-0)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-36-26
WGK Germany: 3
RTECS: FZ7700000
TSCA: Yes
HS Code: 29142900

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 188174
Product name: (+)-4-Cholesten-3-one
Purity: 98%
Packaging: 1g
Price: $33
Updated: 2024/03/01

Sigma-Aldrich

Product number: 188174
Product name: (+)-4-Cholesten-3-one
Purity: 98%
Packaging: 10g
Price: $313
Updated: 2024/03/01

Alfa Aesar

Product number: A11743
Product name: 4-Cholesten-3-one, 98+%
Packaging: 5g
Price: $71.65
Updated: 2024/03/01

Alfa Aesar

Product number: A11743
Product name: 4-Cholesten-3-one, 98+%
Packaging: 25g
Price: $253.65
Updated: 2024/03/01

Cayman Chemical

Product number: 25713
Product name: Cholestenone
Packaging: 5g
Price: $81
Updated: 2024/03/01

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4-Cholesten-3-one Chemical Properties,Usage,Production

Description

Cholestanone is a cholesterol metabolite that has a keto group in place of the 3-hydroxy group on cholesterol. It decreases TGF-β-induced Smad2 phosphorylation and TGF-β expression and prevents inhibition of DNA synthesis by TGF-β in Mv1Lu cells when used at a concentration of 50 μg/ml. Increased fecal excretion of cholestenone is correlated with an increased risk of colorectal cancer. Cholestenone reduces serum cholesterol levels in a variety of animal models but is toxic to rats when administered at doses of 700-1,000 mg/kg per day, inducing hypertrophy in and reducing the activity of the adrenal gland. It has been used as synthetic intermediate in the synthesis of steroids.

Chemical Properties

white to light yellow crystals or powder

Uses

4-Cholesten-3-one is used as a chiral building block for proteomics research. It is an intestinal metabolite of cholesterol and exhibits an anti-obesity effect on animals.

Definition

ChEBI: Cholest-4-en-3-one is a cholestanoid that is cholest-4-ene substituted by an oxo group at position 3. It has a role as a human metabolite and a plant metabolite. It is a cholestanoid and a 3-oxo-Delta(4) steroid.

General Description

Cholestenone is a cholesterol metabolite and analog, which substitutes membrane cholesterol and elevates membrane fluidity.

4-Cholesten-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Cholesten-3-one Suppliers

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View Lastest Price from 4-Cholesten-3-one manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: 4-Cholesten-3-one 601-57-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-31

Hebei Yanxi Chemical Co., Ltd.

Product: 4-Cholesten-3-one 601-57-0
Price: US $20.00-1.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-11-03

Hebei Mujin Biotechnology Co.,Ltd

Product: 4-Cholesten-3-one 601-57-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-10-10

601-57-0, 4-Cholesten-3-oneRelated Search:

Dimethyl sulfoxide Trenbolone 6-Methyl-5-hepten-2-one ETHANE Quinocetone Zearalenone 2-Cyclohexen-1-one Dimethyl sulfide Dimethyl carbonate Dimethyl fumarate Clethodim Dacthal Dimethyl sulfate Dimethyl sebacate N,N-Dimethylformamide Androstenedione Dimethyl ether 2BETA,3BETA,14ALPHA,22[R],25-PENTAHYDROXY-7-CHOLESTEN-6-ONE,2β,3β,14α,22(r),25-pentahydroxy-7-cholesten-6-one

17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecah

17-(1,5-DIMETHYLHEXYL)-10,13-DIMETHYL-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-ONE

(+)-4-CHOLESTEN-3-ONE

4-CHOLESTEN-3-ONE

3-KETO-4-CHOLESTENE

(+)-3-OXO-4-CHOLESTENE

3-OXO-4-CHOLESTENE

CHOLEST-4-ENE-3-ONE

CHOLESTENONE

3-Oxocholest-4-ene

4-Cholestenone

cholest-4-en-3-one

delta4-Cholesten-3-one

(8S,9S,10R,13R,14S,17R)-17-((R)-1,5-DIMETHYL-HEXYL)-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE

10,13-dimethyl-17-(6-methylheptan-2-yl)-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

4-CHOLESTEN-3-ONE, 98+%

(8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

3-Keto-4-cholestene, 3-Oxo-4-cholestene

3-Keto-4-cholestene, 3-Oxo-4-cholestene, 4-Cholesten-3-one

delta(sup 4)-Cholestenone

(20R)-Cholesta-4-ene-3-one

Cholestane-4-ene-3-one

(8S,9S,10R,13R,14S,17R)-10,13-diMethyl-17-((R)-6-Methylheptan-2-yl)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

(+)-4-Cholesten-3-one 98%

4-CHOLESTEN-3-ONE;CHOLESTENONE

(1S,2R,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one

4-Cholestene-3-one

(+)-4-Cholesten-3-one &gt

(+)-4-Cholesten-3-one

(+)-3-Oxo-4-Cholestene

601-57-0

Complex Molecules

Chiral Building Blocks

Asymmetric Synthesis

Steroids

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Steroids

Steroids (Others)

Biochemistry