2-Dimethylaminoisopropyl chloride hydrochloride
- Product Name
- 2-Dimethylaminoisopropyl chloride hydrochloride
- CAS No.
- 4584-49-0
- Chemical Name
- 2-Dimethylaminoisopropyl chloride hydrochloride
- Synonyms
- DMIC;2-DIMETHYLAMINO ISOPROPYL CHLORIDE HCL;1-(DIMETHYLAMINO)-2-CHLOROPROPANE HYDROCHLORIDE;B-DIMETHYLAMINOISOPROPYL CHLORIDE HYDROCHLORIDE;2-DMPC;2-DMPC 99%;DMIC 99%min;Lipoic acid 62-46-4;2-Dimethylaminoisopropyl;intermediate of Methadone
- CBNumber
- CB3235881
- Molecular Formula
- C5H13Cl2N
- Formula Weight
- 158.07
- MOL File
- 4584-49-0.mol
2-Dimethylaminoisopropyl chloride hydrochloride Property
- Melting point:
- 187-190 °C(lit.)
- storage temp.
- Store below +30°C.
- solubility
- 2000g/l
- form
- Crystalline Powder
- color
- White to light cream
- PH
- 5-6 (500g/l, H2O, 20℃)
- Water Solubility
- 2000 g/L (20 º C)
- Sensitive
- Hygroscopic
- BRN
- 3670215
- InChI
- InChI=1S/C5H12ClN.ClH/c1-5(6)4-7(2)3;/h5H,4H2,1-3H3;1H
- InChIKey
- OCWGRWAYARCRTQ-UHFFFAOYSA-N
- SMILES
- C(Cl)(C)CN(C)C.Cl
- CAS DataBase Reference
- 4584-49-0(CAS DataBase Reference)
- EPA Substance Registry System
- 2-Chloro-N,N-dimethyl-1-propanamine hydrochloride (4584-49-0)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- TY1225000
- TSCA
- Yes
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29211980
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D142409
- Product name
- 2-Chloro-N,N-dimethylpropylamine hydrochloride
- Purity
- 98%
- Packaging
- 100g
- Price
- $33.3
- Updated
- 2024/03/01
- Product number
- 8.03240
- Product name
- N-(2-Chloropropyl)-N,N-dimethylammonium chloride
- Purity
- for synthesis
- Packaging
- 250G
- Price
- $95.6
- Updated
- 2024/03/01
- Product number
- D1665
- Product name
- 2-Chloro-1-(dimethylamino)propane Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $24
- Updated
- 2024/03/01
- Product number
- D1665
- Product name
- 2-Chloro-1-(dimethylamino)propane Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 500g
- Price
- $279
- Updated
- 2024/03/01
- Product number
- B20882
- Product name
- 2-Dimethylaminoisopropyl chloride hydrochloride, 98%
- Packaging
- 500g
- Price
- $97.2
- Updated
- 2023/06/20
2-Dimethylaminoisopropyl chloride hydrochloride Chemical Properties,Usage,Production
Chemical Properties
Colourless to pale beige crystalline powder
Uses
2-Chloro-N,N-dimethylpropylamine hydrochloride (DMIC) is used as intermediate for the syntheses of pharmaceuticals (e.g. isothipendyl, methadone and promethazine)
Uses
Hydrochloride salt of 2-Dimethylaminoisopropyl Chloride, used in the synthesis of analogues of lipophilic chalcones, which act as antitubercular agents.
General Description
Off-white chunky solid.
Air & Water Reactions
2-Dimethylaminoisopropyl chloride hydrochloride is hygroscopic. Soluble in water.
Reactivity Profile
2-Dimethylaminoisopropyl chloride hydrochloride is incompatible with strong oxidizing agents. . Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Fire Hazard
Flash point data for 2-Dimethylaminoisopropyl chloride hydrochloride are not available; however, 2-Dimethylaminoisopropyl chloride hydrochloride is probably combustible.
Synthesis
Following the procedure of Schultz and Sprague, J. Am. Chem. Soc., 70, 48 (1948), a solution containing 3.77 g. of 1-dimethylamino-2-propanol and 10 ml. of chloroform was cooled with stirring to a temperature of about 0?? C. A solution of 5.72 g. of freshly distilled thionylchloride in 2 ml. of chloroform was added thereto. The reaction mixture was allowed to come to ambient temperature over a period of about 30 minutes and was then heated to refluxing temperature for an additional 30 minutes. The precipitated material redissolved on heating. 1-Dimethylamino-2-chloropropane hydrochloride began to crystallize from the boiling solvent. The reaction mixture was cooled, diluted with ether and filtered. The reaction product comprising 1-dimethylamino-2-chloropropane hydrochloride weighed about 5.5 g. (95 percent yield). Recrystallization yielded purified 1-dimethylamino-2-chloropropane hydrochloride melting at 192??-194?? C.
2-Dimethylaminoisopropyl chloride hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
2-Dimethylaminoisopropyl chloride hydrochloride Suppliers
- Tel
- --
- Fax
- --
- davide.pessina@deimossrl.it
- Country
- Italy
- ProdList
- 601
- Advantage
- 58
View Lastest Price from 2-Dimethylaminoisopropyl chloride hydrochloride manufacturers
- Product
- 2-DMPC 4584-49-0
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2024-05-25
- Product
- 2-Dimethylaminoisopropyl chloride hydrochloride 4584-49-0
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100mt
- Release date
- 2020-11-05
- Product
- 2-Dimethylaminoisopropyl chloride hydrochloride 4584-49-0
- Price
- US $100.00-70.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2024-08-16