ChemicalBook > CAS DataBase List > 5α-Cholestane

5α-Cholestane

Product Name: 5α-Cholestane
CAS No.: 481-21-0
Chemical Name: 5α-Cholestane
Synonyms: CHOLESTANE;NSC 224419;α-Cholestane;5α-Cholestane;5-α-cholestane;Cholestane(5α);(5A)-CHOLESTANE;alpha-Cholestane;5ALPHA-CHOLESTANE;Cholestane, (5α)-
CBNumber: CB3239829
Molecular Formula: C27H48
Formula Weight: 372.67
MOL File: 481-21-0.mol

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5α-Cholestane Property

Melting point:: 78-80 °C
Boiling point:: 250 °C (1 mmHg)
Density: 0.9090
refractive index: 1.4887
storage temp.: room temp
solubility: DMF: 1 mg/ml
DMSO: 0.1 mg/ml
Ethanol: 20 mg/ml
Ethanol: PBS (pH 7.2)(1:2): 0.1 mg/mlPBS (pH 7.2): 0.1 mg/ml
form: Crystalline Powder
color: White
Merck: 13,2219
BRN: 2051806
LogP: 11.945 (est)
CAS DataBase Reference: 481-21-0(CAS DataBase Reference)
EPA Substance Registry System: Cholestane, (5.alpha.)- (481-21-0)

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Safety

Hazard Codes: Xn
Risk Statements: 22-38-40-48/20/22-67-36/38-20-63
Safety Statements: 24/25-36/37-26
RIDADR: UN 1888 6.1/PG 3
WGK Germany: 3
HS Code: 29021990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H336May cause drowsiness or dizziness

H351Suspected of causing cancer

H372Causes damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C8003
Product name: 5α-Cholestane
Purity: ≥97.0% (HPLC)
Packaging: 1g
Price: $195.04
Updated: 2025/07/31

Sigma-Aldrich

Product number: C8003
Product name: 5α-Cholestane
Purity: ≥97.0% (HPLC)
Packaging: 5g
Price: $836
Updated: 2025/07/31

Sigma-Aldrich

Product number: 47124
Product name: 5-α-Cholestane
Purity: certified reference material, 10?mg/mL in chloroform
Packaging: 1ML
Price: $53.29
Updated: 2025/07/31

Sigma-Aldrich

Product number: R205370
Product name: 5-ALPHA-CHOLESTANE
Purity: AldrichCPR
Packaging: 1MG
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 26763
Product name: 5α-Cholestane
Packaging: 500mg
Price: $92
Updated: 2024/03/01

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5α-Cholestane Chemical Properties,Usage,Production

Description

5α-Cholestane is a sterol that has been found in dust samples from urban and rural paved and agricultural and public unpaved roads. It has been used as an internal standard for the quantification of phytosterols by HPLC-MS/MS and fecal sterols by GC-FID and GC-MS.

Chemical Properties

WHITE CRYSTALLINE POWDER

Uses

5α-Cholestane was used as standard in cholesterol analysis by GC and HPLC.

Uses

α-Cholestane is the trans-decalin homolog of Coprostane.

Definition

ChEBI: The 5alpha-stereoisomer of cholestane.

Biochem/physiol Actions

5α-Cholestane is a sterol produced endogenously from cholesterol and has been isolated from human feces. It is derived from cholesterol by the action of intestinal microorganisms. Derivatives of 5α-cholestane in plants are called Brassinosteroids that selectively activate the PPI3K/Akt pathway.

Purification Methods

Crystallise 5-cholestane from Et2O/EtOH or EtOAc. [Ruzicka et al. Helv Chim Acta 16 327 1933, Beilstein 5 III 1132, 5 IV 1227.]

References

[1] W. ROGGE B S P Medeiros. Organic Compounds in Dust from Rural and Urban Paved and Unpaved Roads Taken During the San Joaquin Valley Fugitive Dust Characterization Study[J]. Environmental Engineering Science, 2012, 25 1: 1-13. DOI: 10.1089/ees.2010.0124
[2] SUKANYA MINGYAI. Effects of Extraction Methods on Phytochemicals of Rice Bran Oils Produced from Colored Rice.[J]. Journal of oleo science, 2018, 67 2: 135-142. DOI: 10.5650/jos.ess17122
[3] CAROLINE SCH?NNING; Thor A S; Rhys Leeming. Faecal contamination of source-separated human urine based on the content of faecal sterols[J]. Water Research, 2002, 36 8: Pages 1965-1972. DOI: 10.1016/s0043-1354(01)00427-4

5α-Cholestane Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5α-Cholestane manufacturers

Career Henan Chemical Co

Product: 5α-Cholestane 481-21-0
Price: US $1.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-24

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481-21-0

C27H48

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