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GW 842166X

Product Name
GW 842166X
CAS No.
666260-75-9
Chemical Name
GW 842166X
Synonyms
CS-631;GW 842166;GW 842166X;GW842166X;GW 842166;GW842166X/GW-842166X;GW 842166X USP/EP/BP;2-(2,4-dichloroanilino)-N-(oxan-4-ylmethyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide;2-(2,4-dichlorophenylamino)-N-((tetrahydro-2H-pyran-4-yl)methyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide;2-(2,4-Dichlorophenylamino)-4-trifluoromethylpyrimidine-5-carboxylic acid [(tetrahydropyran-4-yl)methyl]amide;5-Pyrimidinecarboxamide, 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro-2H-pyran-4-yl)methyl]-4-(trifluoromethyl)-
CBNumber
CB32455643
Molecular Formula
C18H17Cl2F3N4O2
Formula Weight
449.25
MOL File
666260-75-9.mol
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GW 842166X Property

storage temp. 
Store at -20°C
solubility 
DMF:20.0(Max Conc. mg/mL);44.52(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.56(Max Conc. mM)
DMSO:37.77(Max Conc. mg/mL);84.07(Max Conc. mM)
Ethanol:0.3(Max Conc. mg/mL);0.67(Max Conc. mM)
form 
Powder
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10010372
Product name
GW 842166X
Purity
≥98%
Packaging
1mg
Price
$22
Updated
2024/03/01
Cayman Chemical
Product number
10010372
Product name
GW 842166X
Purity
≥98%
Packaging
5mg
Price
$95
Updated
2024/03/01
Cayman Chemical
Product number
10010372
Product name
GW 842166X
Purity
≥98%
Packaging
10mg
Price
$168
Updated
2024/03/01
Cayman Chemical
Product number
10010372
Product name
GW 842166X
Purity
≥98%
Packaging
25mg
Price
$319
Updated
2024/03/01
TRC
Product number
G931520
Product name
GW-842166X
Packaging
25mg
Price
$370
Updated
2021/12/16
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GW 842166X Chemical Properties,Usage,Production

Description

The peripheral cannabinoid (CB2) receptor is a G protein-coupled receptor (GPCR) that is localized predominantly in immune cells, monocytes, macrophages, and in several peripheral organs and binds the active component of cannabis, Δ9-tetrahydrocannabinol, as well as anandamide, an endogenous CB receptor ligand. GW 842166X is a peripheral cannabinoid (CB2) receptor agonist with ED50 values of 91 and 63 nM in rat and human, respectively. When administered orally to rats in the Freund’s complete adjuvant (FCA) model of inflammatory pain, GW 842166X is highly potent with an ED50 value of 0.1 mg/kg and full reversal of hyperalgesia at 0.3 mg/kg.

Uses

GW-842166X is pyrimidine ester based compound that is known as a highly selective CB2 receptor agonist for the treatment of inflammatory and neuropathic pain.

Definition

ChEBI: 5-pyrimidinecarboxamide, 2-[(2,4-dichlorophenyl)amino]-n-[(tetrahydro-2h-pyran-4-yl)methyl]-4-(trifluoromethyl)- is a dichlorobenzene.

GW 842166X Preparation Products And Raw materials

Raw materials

Preparation Products

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GW 842166X Suppliers

Canada 1 China 84 United States 13 Global 98
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
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View Lastest Price from GW 842166X manufacturers

Career Henan Chemical Co
Product
GW842166X 666260-75-9
Price
US $1.00/g
Min. Order
1g
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-10

666260-75-9, GW 842166XRelated Search:

CHLOROPHENYLSILANE 97 Phenylsilane Benzeneruthenium(II) chloride dimer Phenyl dichlorophosphate Phenyltrichlorosilane WY-14643 SIRTINOL Rimonabant DAPT 17-DMAG GW 842166X

  • GW 842166X
  • GW 842166
  • GW842166X/GW-842166X
  • 2-(2,4-Dichlorophenylamino)-4-trifluoromethylpyrimidine-5-carboxylic acid [(tetrahydropyran-4-yl)methyl]amide
  • 2-(2,4-dichlorophenylamino)-N-((tetrahydro-2H-pyran-4-yl)methyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide
  • 2-(2,4-dichloroanilino)-N-(oxan-4-ylmethyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide
  • GW842166X;GW 842166
  • CS-631
  • 5-Pyrimidinecarboxamide, 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro-2H-pyran-4-yl)methyl]-4-(trifluoromethyl)-
  • GW 842166X USP/EP/BP
  • 666260-75-9
  • C18H17Cl2F3N4O2
  • Inhibitors