Necitumumab

Product Name: Necitumumab
CAS No.: 906805-06-9
Chemical Name: Necitumumab
Synonyms: Necitumumab;IMC-11F8/LY301221;Necitumumab (anti-EGFR);Research Grade Necitumumab;Research Grade Necitumumab(DHB86901)
CBNumber: CB33044071
Formula Weight: 0
MOL File: Mol file

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Necitumumab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Necitumumab Chemical Properties,Usage,Production

Uses

Necitumumab is a human IgG monoclonal antibody directed against EGFR. Necitumumab can be used for research of NSCLC, colorectal cancer, etc[1].

Clinical Use

IgG1 monoclonal antibody:
Treatment of locally advanced or metastatic epidermal growth factor receptor (EGFR) expressing squamous non-small cell lung cancer

Drug interactions

Potentially hazardous interactions with other drugs
Live vaccines: avoid concomitant use.

Metabolism

The elimination routes of necitumumab are only partially documented, and involve degradation to peptides after being internalised into its target cells, proteolysis within the liver or the reticuloendothelial system, as well as nonspecific endocytosis.

References

[1] Garnock-Jones KP. Necitumumab: First Global Approval. Drugs. 2016 Feb;76(2):283-9. DOI:10.1007/s40265-015-0537-0

Necitumumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Necitumumab Suppliers

China 21 United States 1 Global 22

Shanghai Synchem Pharma Co., ltd

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Biolab Reagents

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Wuhan Jingkangen Biomedical Technology Co., Ltd

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906805-06-9, NecitumumabRelated Search:

Fresolimumab Telisotuzumab Drozitumab Cinpanemab Emactuzumab Omalizumab Tucotuzumab Celmoleukin Nidanilimab Lenzilumab Odronextamab

IMC-11F8/LY301221

Necitumumab

Research Grade Necitumumab(DHB86901)

Necitumumab (anti-EGFR)

Research Grade Necitumumab

906805-06-9