N,N,N',N'-Tetramethylazodicarboxamide

ChemicalBook > CAS DataBase List > N,N,N',N'-Tetramethylazodicarboxamide

N,N,N',N'-Tetramethylazodicarboxamide

Description References

Product Name: N,N,N',N'-Tetramethylazodicarboxamide
CAS No.: 10465-78-8
Chemical Name: N,N,N',N'-Tetramethylazodicarboxamide
Synonyms: TMAD;DIAMIDE;Tetramethylazodicarboxamide;N1,N1,N2,N2-Tetramethyldiazene-1,2-dicarboxamide;(3E)-3-(dimethylcarbamoylimino)-1,1-dimethyl-urea;(E)-1-[(dimethylcarbamoyl)imino]-3,3-dimethylurea;Nsc143013;Diamide ,98%;Diamide, 98%, for synthesis;Azobis(N,N-dimethylformamide)
CBNumber: CB3340747
Molecular Formula: C6H12N4O2
Formula Weight: 172.19
MOL File: 10465-78-8.mol

Less

N,N,N',N'-Tetramethylazodicarboxamide Property

Melting point:: 112 °C
Boiling point:: 220.4±23.0 °C(Predicted)
Density: 1.13±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: soluble in Methanol
form: crystalline
pka: -0?+-.0.70(Predicted)
color: yellow
BRN: 1910409
InChI: InChI=1S/C6H12N4O2/c1-9(2)5(11)7-8-6(12)10(3)4/h1-4H3/b8-7+
InChIKey: VLSDXINSOMDCBK-BQYQJAHWSA-N
SMILES: C(=O)(/N=N/C(=O)N(C)C)N(C)C
CAS DataBase Reference: 10465-78-8(CAS DataBase Reference)

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3
RTECS: LQ1041000
F: 4.10
HS Code: 29270000

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D3648
Product name: Diamide
Packaging: 1g
Price: $143
Updated: 2024/03/01

Sigma-Aldrich

Product number: D3648
Product name: Diamide
Packaging: 5g
Price: $629
Updated: 2024/03/01

TCI Chemical

Product number: A1458
Product name: 1,1'-Azobis(N,N-dimethylformamide)
Purity: >97.0%(T)
Packaging: 1g
Price: $23
Updated: 2024/03/01

TCI Chemical

Product number: A1458
Product name: 1,1'-Azobis(N,N-dimethylformamide)
Purity: >97.0%(T)
Packaging: 5g
Price: $84
Updated: 2024/03/01

Alfa Aesar

Product number: J64865
Product name: 1,1'-Azobis(N,N-dimethylformamide), 95%
Packaging: 1g
Price: $140
Updated: 2024/03/01

Less

N,N,N',N'-Tetramethylazodicarboxamide Chemical Properties,Usage,Production

Description

N,N,N’,N’-Tetramethylazodicarboxamide (also named as Diamide, TMAD) is a reagent used for the oxidization of thiols in proteins. It is used as a reagent in the Mitsunobu reaction in place of diethyl azodicarboxylate. It can be used to titrate protein gluotathiolation to discriminate from other protein modifications.

References

N. S. Kosower, E. M. Kosower, Diamide: A oxidant probe for this, Methods in Enzymology, 1995, vol. 251, pp. 123133

Chemical Properties

Yellow crystals

Uses

Reported to be of use as a thiol oxidizing agent. Diamide has been used to titrate protein glutathiolation to discriminate from other oxidative protein modifications. Treatment increased protein glutathiolation in a concentration-dependent manner and had comparably little effect on protein-protein disulfide formation.

Definition

ChEBI: 1,1'-azobis(N,N-dimethylformamide) is a monoazo compound.

Synthesis Reference(s)

The Journal of Organic Chemistry, 38, p. 1652, 1973 DOI: 10.1021/jo00949a007

N,N,N',N'-Tetramethylazodicarboxamide Preparation Products And Raw materials

Raw materials

Silver oxide Triethylamine Dimethylcarbamoyl chloride Dichloromethane HYDRAZINE

Preparation Products

Less

N,N,N',N'-Tetramethylazodicarboxamide Suppliers

Americas 1 China 136 Czech Republic 1 Europe 3 Germany 3 India 5 Japan 2 Switzerland 1 United Kingdom 8 United States 27 Global 187

Suzhou Highfine Biotech Co., Ltd

Tel: 0512-68311833 13962195826
Fax: 0512-68417696
Email: wuhao@highfine.com
Country: China
ProdList: 498
Advantage: 75

Suzhou BEC Biological Technology Co., Ltd

Tel: +86-512-68095917 13862064516
Fax: +86-512-68417933
Email: sales@bek.com.cn
Country: China
ProdList: 145
Advantage: 59

SuZhou Jonathan New Material Technology Co., Ltd.

Tel: 0512-68312916,63926215 18912725070
Fax: 0512-68417933
Email: jon@jonnmt.com
Country: China
ProdList: 114
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: sales@accelachem.com
Country: China
ProdList: 11728
Advantage: 58

Changzhou Jianuokang Pharmaceutical Co., Ltd.

Tel: 0519-85202684; 13775120798
Fax: 0519-85202684
Email: jnkpharmtech@163.com
Country: China
ProdList: 295
Advantage: 55

Shanghai Hansi Chemical Industry Co., Ltd.

Tel: 17717618050
Email: zllg@gh-reagent.com
Country: China
ProdList: 10424
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

PharmaBlock Sciences (Nanjing),Inc.

Tel: 400-0255188 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 4986
Advantage: 55

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169097
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12458
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9551
Advantage: 66

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: +8613162137806 18575662672
Fax: 021 51613951
Email: mzeng@3wpharm.com
Country: China
ProdList: 9747
Advantage: 57

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 4550
Advantage: 62

ZhengZhou HuaWen Chemical Co.Ltd

Tel: 0370-2785118 15343847665
Fax: QQ：3470079902
Email: huawenchem@163.com
Country: China
ProdList: 3205
Advantage: 55

Shanghai Shenyue Chemical Co., Ltd.

Tel: 021-021-52212593 15300879511
Fax: +86 (21) 51062076
Email: sales@nuohey.com
Country: China
ProdList: 6135
Advantage: 60

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9872
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17779
Advantage: 75

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12338
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9452
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19918
Advantage: 55

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9906
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8033
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7934
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41438
Advantage: 60

Shanghai DiBai Chemicals Co., Ltd.

Tel: 021-54359730 400-008-9730
Fax: 021-54353864
Email: info@chemxyz.com
Country: China
ProdList: 3993
Advantage: 60

Shanghai URChem Limited

Tel: 021-50890968 +86-18601776121;
Fax: 086-21-68416099 58604179
Email: danny@urchem.com
Country: China
ProdList: 517
Advantage: 58

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9636
Advantage: 58

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5223
Advantage: 58

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 17501653713 17501653715
Email: xingui2022@126.com
Country: China
ProdList: 10033
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15878
Advantage: 55

Shanghai Song Yuan Chemical Technology Co., Ltd.

Tel: 010-1234567 18521000990
Fax: 86-021-33275113
Email: sonyuanchemical@163.com
Country: China
ProdList: 6490
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Quzhou Rundong Chemical (Technology) Co.

Tel: 0570-8789886 18892685668
Fax: 0570-8789985
Email: info@rundongchemical.com
Country: China
ProdList: 3989
Advantage: 60

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9958
Advantage: 56

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9638
Advantage: 58

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 3496
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27322
Advantage: 60

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9604
Advantage: 55

Grader reagent

Tel: 18221735425
Email: sales@xinpingchem.com
Country: China
ProdList: 9951
Advantage: 58

Shanghai Chaolan Chemical Technology Center

Tel: QQ:65489617 15618227136
Fax: 21-5161 9052
Email: info@SuperLan-chem.com
Country: China
ProdList: 9737
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Shenzhen Sendi Biological Technology Co., Ltd.

Tel: 18124570582 TEL：0755-23574479 2355327139
Fax: 0755-23229476 QQ: 2355327139
Email: siliao02@yccreate.com
Country: China
ProdList: 6120
Advantage: 58

Shanghai Kangman Biological Technology Co., Ltd.

Tel: 18800375331
Fax: 021-50908862
Email: kangmansales@163.com
Country: China
ProdList: 7580
Advantage: 55

Zhengzhou Huiju Chemical Co., Ltd.

Tel: 0371-55900031 18137872243
Fax: QQ：2853979815
Email: 2853979815@qq.com
Country: China
ProdList: 10004
Advantage: 55

Taian Jiaye Biotechnology Co.Ltd

Tel: 13127280945
Email: 285424065@qq.com
Country: China
ProdList: 9980
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28821
Advantage: 58

Less

View Lastest Price from N,N,N',N'-Tetramethylazodicarboxamide manufacturers

Career Henan Chemical Co

Product: N,N,N',N'-Tetramethylazodicarboxamide 10465-78-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2018-08-06

10465-78-8, N,N,N',N'-TetramethylazodicarboxamideRelated Search:

Di-tert-Butyl azodicarboxylate N,N-Dimethylformamide Polyacrylamide Metformin PHTHALAMIDE 1,1'-(Azodicarbonyl)-dipiperidine Azodicarbonamide Pentamethyldiethylenetriamine Diethyl azodicarboxylate Dibenzyl azodicarboxylate Diisopropyl azodicarboxylate 1,8-Bis(dimethylamino)naphthalene N,N,N',N'-Tetraphenylbenzidine N,N,N',N'-TETRAMETHYLDIAMINOMETHANE AZODICARBOXYLIC BISMORPHOLIDE 1,1-DIMETHYLUREA Formamide N,N,N',N'-Tetramethylazodicarboxamide

AZODICARBOXYLIC ACID BIS[DIMETHYLAMIDE]

DIAMIDE

DIAZINE-DICARBOXYLIC ACID BIS[N,N-DIMETHYLAMIDE]

1,1'-AZOBIS(N,N'-DIMETHYLFORMAMIDE)

1,1'-AZOBIS(N,N-DIMETHYLFORMAMIDE)

N,N,N',N'-TETRAMETHYLAZODICARBAMIDE

N,N,N',N'-TETRAMETHYLAZODICARBOXAMIDE

1,1’-azobis(n,n-dimethyl-formamid

n,n,n’,n’-tetramethylazoformamide

Diamide N,N,N',N'-Tetramethylazodicarboxamide

Azodicarboxylic acid bis(dimethylamide), diamide

N1,N1,N2,N2-Tetramethyldiazene-1,2-dicarboxamide

TMAD N,N,N',N'-tetramethylazodicarboxamide

1,1'-Azobis(N,N-dimethylformamide)≥ 98%(Titration)

N,N,N',N'-Tetramethylazobisformamide

Nsc143013

N,N,N',N'-Tetramethylazodicarboxamide(TMAD)

Diamide ,98%

1-[(diMethylcarbaMoyl)iMino]-3,3-diMethylurea

tetramethyl-diazenedicarboxamid

tetramethyldiazenedicarboxamide

1,1-Azobis(N,N-dimethylforamide)

3-(N,N-dimethylcarbamoylimido)-1,1-dimethylurea

Diamide 1,1-Azobis(N,N-dimethylformamide)

blowing (and foaming) agent AC

Tetramethylazodicarboxamide

3-(Dimethylcarbamoylimino)-1,1-dimethylurea

Diazenedicarboxamide, tetramethyl-

Azobis(N,N-dimethylformamide)

N,N,N',N'-Tetramethyldiazene-1,2-dicarboxamide

N,N,N',N'-Tetramethyldiazenedicarboxamide

TMAD

1,1'-Azobis(N,N-dimethylformamide),98%

Tetramethylazodicarboxamide(TMAD)

(3E)-3-(dimethylcarbamoylimino)-1,1-dimethyl-urea

1,1μ-Azobis(N,N-dimethylformamide), Azodicarboxylic acid bis(dimethylamide), Diazinedicarboxylic acid bis(N,N-dimethylamide), N,N,Nμ,Nμ-Tetramethylazodicarboxamide

Azodicarboxylic acid bis(dimethylamide), diamide, Diamide, Diazinedicarboxylic acid bis(N,N-dimethylamide), N,N,Nμ,Nμ-Tetramethylazodicarboxamide

1,1′-Azobis(N,N-dimethylformamide), Azodicarboxylic acid bis(dimethylamide)

Diazenedicarboxylic acid bis(N,N-dimethylamide)

Formamide, 1,1'-azobis[N,N-dimethyl-

1,1'-Azobis(N,N-dimethylformamide) &gt

Diamide, 98%, for synthesis

1,2-Diazenedicarboxamide, N1,N1,N2,N2-tetramethyl-

N,N,N',N'-Tetramethylazodicarboxamide ISO 9001：2015 REACH

(E)-1-[(dimethylcarbamoyl)imino]-3,3-dimethylurea

TIANFU-CHEM CAS:10465-78-8 N,N,N',N'-Tetramethylazodicarboxamide

(E)-N1,N1,N2,N2-tetramethyldiazene-1,2-dicarboxamide

N,N,N',N'-Tetramethylazodicarboxamide

10465-78-8

CH32NCONNCONCH32

Amides

BioChemical

Building Blocks

Biochemicals and Reagents

Carbonyl Compounds

Glyceraldehyde 3-Phosphate Dehydrogenase from a green algae

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors by Enzyme