Balsalazide disodium
- Product Name
- Balsalazide disodium
- CAS No.
- 150399-21-6
- Chemical Name
- Balsalazide disodium
- Synonyms
- BALOFLOXACIN;BALSALAZIDE SODIUM;Balsazide Disodium;BALSALZIDE DISODIUM;Balsalazie DisodiuM;Balsalazide disodium;BALSALAZIDEDISODOUMSALT;Balsalazide Disodium USP;Balsalazide (sodium hydrate);Balsalazide Disodium Hydrate
- CBNumber
- CB3367030
- Molecular Formula
- C17H18N3NaO7
- Formula Weight
- 399.33
- MOL File
- 150399-21-6.mol
Balsalazide disodium Property
- Melting point:
- >195°C (dec.)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- Yellow
- Merck
- 14,945
- InChIKey
- XDCNKOBSQURQOZ-MVIJUDHYSA-L
- SMILES
- C(C1C(=CC=C(/N=N/C2C=CC(C(=O)NCCC(=O)O)=CC=2)C=1)O)(=O)O.[NaH].O
Safety
- HS Code
- 2927000000
N-Bromosuccinimide Price
- Product number
- 1048255
- Product name
- Balsalazide disodium
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200MG
- Price
- $450
- Updated
- 2025/07/31
- Product number
- B4121
- Product name
- Balsalazide Disodium Salt Dihydrate
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 1g
- Price
- $112
- Updated
- 2025/07/31
- Product number
- B4121
- Product name
- Balsalazide Disodium Salt Dihydrate
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 5g
- Price
- $376
- Updated
- 2024/03/01
- Product number
- B116295
- Product name
- BalsalazideDisodiumDihydrate
- Packaging
- 10mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- B116295
- Product name
- BalsalazideDisodiumDihydrate
- Packaging
- 25mg
- Price
- $250
- Updated
- 2021/12/16
Balsalazide disodium Chemical Properties,Usage,Production
Uses
antiinflammatory
Uses
Balsalazide Disodium Dihydrate is an analogue of Sulfasalazine (S699084), A prodrug of 5-aminosalicylic acid where carrier molecule is 4-aminobenzoyl-β-alanine. Anti-inflammatory (gastrointestinal).
Definition
ChEBI: The dihydrate of the disodium salt of balsalazide. A prodrug, releasing the anti-inflammatory 5-aminosalicylic acid (mesalazine) in the large intestine, it is used in the treatment of ulcerative colitis.
Indications
Balsalazide disodium is delivered intact to the colon, where it is cleaved by bacterial azoreduction to release equimolar quantities of mesalamine, the therapeutically active portion of the molecule, and 4-aminobenzoyl-β-alanine; the latter compound is only minimally absorbed and is largely inert.
brand name
Colazal (Salix).
in vivo
At the endpoint, the protein production of MIP-1β, MCP-1, IL-6, and IL-10 in the colon tissues decrease in concordance with the plasma concentrations of the cytokines. The drug-treated groups reveal lower expression of p-STAT3 compared to the CAC group. In addition, BCL2 decreases and BAX increases markedly in the BSZ+VSL#3 group[1]. Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug[2].
IC 50
IL-6; IL-1; STAT3
Balsalazide disodium Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Balsalazide disodium manufacturers
- Product
- Balsalazide disodium 150399-21-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20tons
- Release date
- 2025-01-02
- Product
- Balsalazide disodium 150399-21-6
- Price
- US $150.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2024-12-17
- Product
- Balsalazide disodium 150399-21-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 200KG
- Release date
- 2019-08-30