Balsalazide disodium

Product Name: Balsalazide disodium
CAS No.: 150399-21-6
Chemical Name: Balsalazide disodium
Synonyms: BALOFLOXACIN;BALSALAZIDE SODIUM;Balsazide Disodium;BALSALZIDE DISODIUM;Balsalazie DisodiuM;Balsalazide disodium;BALSALAZIDEDISODOUMSALT;Balsalazide Disodium USP;Balsalazide (sodium hydrate);Balsalazide Disodium Hydrate
CBNumber: CB3367030
Molecular Formula: C17H18N3NaO7
Formula Weight: 399.33
MOL File: 150399-21-6.mol

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Balsalazide disodium Property

Melting point:: >195°C (dec.)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form: Solid
color: Yellow
Merck: 14,945
InChIKey: XDCNKOBSQURQOZ-MVIJUDHYSA-L
SMILES: C(C1C(=CC=C(/N=N/C2C=CC(C(=O)NCCC(=O)O)=CC=2)C=1)O)(=O)O.[NaH].O

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Safety

HS Code: 2927000000

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1048255
Product name: Balsalazide disodium
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200MG
Price: $450
Updated: 2025/07/31

TCI Chemical

Product number: B4121
Product name: Balsalazide Disodium Salt Dihydrate
Purity: >98.0%(HPLC)(N)
Packaging: 1g
Price: $112
Updated: 2025/07/31

TCI Chemical

Product number: B4121
Product name: Balsalazide Disodium Salt Dihydrate
Purity: >98.0%(HPLC)(N)
Packaging: 5g
Price: $376
Updated: 2024/03/01

TRC

Product number: B116295
Product name: BalsalazideDisodiumDihydrate
Packaging: 10mg
Price: $130
Updated: 2021/12/16

TRC

Product number: B116295
Product name: BalsalazideDisodiumDihydrate
Packaging: 25mg
Price: $250
Updated: 2021/12/16

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Balsalazide disodium Chemical Properties,Usage,Production

Uses

antiinflammatory

Uses

Balsalazide Disodium Dihydrate is an analogue of Sulfasalazine (S699084), A prodrug of 5-aminosalicylic acid where carrier molecule is 4-aminobenzoyl-β-alanine. Anti-inflammatory (gastrointestinal).

Definition

ChEBI: The dihydrate of the disodium salt of balsalazide. A prodrug, releasing the anti-inflammatory 5-aminosalicylic acid (mesalazine) in the large intestine, it is used in the treatment of ulcerative colitis.

Indications

Balsalazide disodium is delivered intact to the colon, where it is cleaved by bacterial azoreduction to release equimolar quantities of mesalamine, the therapeutically active portion of the molecule, and 4-aminobenzoyl-β-alanine; the latter compound is only minimally absorbed and is largely inert.

brand name

Colazal (Salix).

in vivo

At the endpoint, the protein production of MIP-1β, MCP-1, IL-6, and IL-10 in the colon tissues decrease in concordance with the plasma concentrations of the cytokines. The drug-treated groups reveal lower expression of p-STAT3 compared to the CAC group. In addition, BCL2 decreases and BAX increases markedly in the BSZ+VSL#3 group^[1]. Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug^[2].

IC 50

IL-6; IL-1; STAT3

Balsalazide disodium Preparation Products And Raw materials

Raw materials

Preparation Products

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Balsalazide disodium Suppliers

Americas 1 Belgium 2 Canada 1 China 131 Cyprus 1 Europe 4 Germany 3 India 16 Japan 1 Poland 1 South Africa 1 United Arab Emirates 1 United Kingdom 12 United States 22 Global 197

LGM Pharma

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View Lastest Price from Balsalazide disodium manufacturers

Sinoway Industrial co., ltd.

Product: Balsalazide disodium 150399-21-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2025-01-02

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Balsalazide disodium 150399-21-6
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-12-17

Career Henan Chemical Co

Product: Balsalazide disodium 150399-21-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 200KG
Release date: 2019-08-30

150399-21-6, Balsalazide disodiumRelated Search:

Sodium Phosphate, Dibasic LACTOSE, MONOHYDRATE Pemetrexed Disodium Fructose sodium diphosphate PHENYL VALERATE PYRAZOPHOS Sulfasalazine CHLOROPHOSPHONAZO III Ethylenediaminetetraacetic acid disodium salt Diphenyl ether CARBONYL SULFIDE Disodium edetate dihydrate ERBIUM (III) 2,4-PENTANEDIONATE Phenyl salicylate PHENYL RESIN BALSALAZIDE DISODIUM SALT Phenylacetic acid BALOFLOXACIN,BALOFLOXACIN 98.5% EXTRA PURE,BALOFLOXACIN 98.5%,Balofloxacin425.46

BALSALAZIDE DISODIUM SALT DIHYDRATE

BALSALAZIDE DISODIUM DIHYDRATE

BALSALAZIDE SODIUM

BALSALZIDE DISODIUM

(E)-5-[[4-[[(2-CARBOXYETHYL)AMINO]CARBONYL]PHENYL]AZO]-2-HYDROXYBENZOIC ACID, DISODIUM SALT, DIHYDRATE

BALSALAZIDE DISODIUM 2-HYDRATE

BALSALAZIDEDISODOUMSALT

(E)-5-[[4-[[(2-Carboxyethyl)amino]-carbonyl]phenyl]azo-2-hydroxy-benzoic acid disodium salt

Balsalazide disodium

BALOFLOXACIN

Balsazide Disodium

Balsalazie DisodiuM

Balsalzide disodium dihydrate

Balsalazide Disodium (200 mg)

(3Z)-3-(2-{4-[(2-carboxyethyl)carbaMoyl]phenyl}hydrazin-1-ylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid

Benzoic acid,5-[(1E)-2-[4-[[(2-carboxyethyl)aMino]carbonyl]phenyl]diazenyl]-2-hydroxy-,sodiuM salt, hydrate (1:2:2)

Balsalazide (sodium hydrate)

Balsalazide Disodium Hydrate

disodium 3-[[4-[(2-carboxylatoethylamino)-oxomethyl]phenyl]hydrazinylidene]-6-oxo-1-cyclohexa-1,4-dienecarboxylate dihydrate

Balsalazide Disodium Salt Dihydrate&gt

5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic Acid Disodium Salt

Balsalazide disodium dihydrateQ: What is Balsalazide disodium dihydrate Q: What is the CAS Number of Balsalazide disodium dihydrate Q: What is the storage condition of Balsalazide disodium dihydrate Q: What are the applications of Balsalazide disodium dihydrate

Balsalazide Disodium (1048255)

5-[(1E)-2-[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]diazenyl]-2-hydroxy-Benzoic acid sodium salt hydrate (1:2:2)

Balsalazide Disodium Salt Dihydrate, ≥ 98.0%

Balsalazide Disodium USP

Sodium (E)-5-((4-((2-carboxylatoethyl)carbamoyl)phenyl)diazenyl)-2-hydroxybenzoate dihydrate

Balsalazide sodium hydrate, 10 mM in DMSO

150399-21-6

150339-21-6

0399-21-6

C17H13N3Na2O62H2O

C17H13N3O6Na22H2O

C17H17N3Na2O8

C17H15N3O62H2O2Na

COLAZAL

Intermediates