Methyl 2-aminothiazole-5-carboxylate
- Product Name
- Methyl 2-aminothiazole-5-carboxylate
- CAS No.
- 6633-61-0
- Chemical Name
- Methyl 2-aminothiazole-5-carboxylate
- Synonyms
- NSC 42123;RARECHEM AL BF 1263;2-aminothiazole-5-carboxylate;2-aminothiazole-5-methyl formate;2-AMino-5-(Methoxycarbonyl)thiazole;Methyl 2-AMino-5-thiazolecarboxylate;METHYL 2-AMINOTHIAZOLE-5-CARBOXYLATE;Methyl 2-Aminothioazole-5-carboxylate;2-Amino-5-(methoxycarbonyl)-1,3-thiazole;Methyl 2-Aminothiazole-5-carboxylate >
- CBNumber
- CB3428872
- Molecular Formula
- C5H6N2O2S
- Formula Weight
- 158.18
- MOL File
- 6633-61-0.mol
Methyl 2-aminothiazole-5-carboxylate Property
- Melting point:
- 182-186°C
- Boiling point:
- 298.7±13.0 °C(Predicted)
- Density
- 1.408±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 3.02±0.10(Predicted)
- form
- Solid
- color
- Tan to Light Brown
- InChI
- InChI=1S/C5H6N2O2S/c1-9-4(8)3-2-7-5(6)10-3/h2H,1H3,(H2,6,7)
- InChIKey
- UJNNCGWBDJHCEM-UHFFFAOYSA-N
- SMILES
- S1C(C(OC)=O)=CN=C1N
- CAS DataBase Reference
- 6633-61-0(CAS DataBase Reference)
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- Hazard Note
- Harmful
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M2598
- Product name
- Methyl 2-Aminothiazole-5-carboxylate
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $56
- Updated
- 2025/07/31
- Product number
- M2598
- Product name
- Methyl 2-Aminothiazole-5-carboxylate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $223
- Updated
- 2025/07/31
- Product number
- M287280
- Product name
- Methyl 2-Aminothiazole-5-carboxylate
- Packaging
- 5G
- Price
- $55
- Updated
- 2021/12/16
- Product number
- J94046
- Product name
- Methyl 2-Aminothiazole-5-carboxylate
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- 066969
- Product name
- Methyl2-Amino-1,3-thiazole-5-carboxylate
- Purity
- 97%
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
Methyl 2-aminothiazole-5-carboxylate Chemical Properties,Usage,Production
Uses
Methyl 2-Aminothiazole-5-carboxylate (cas# 6633-61-0) is a compound useful in organic synthesis.
Synthesis
20656-61-5
17356-08-0
6633-61-0
General procedure for the synthesis of methyl 2-aminothiazole-5-carboxylate from methyl 2-chloro-3-oxopropionate and compound (CAS:17356-08-0): a mixture of 2.4 g of methyl 2-chloro-3-oxopropionate, 20 mL of water, and 1.75 g of thiourea was refluxed for 2 hours. Upon completion of the reaction, the mixture was cooled to room temperature, decolorized by adding 0.25 g of activated carbon (Norit) and filtered. The filtrate was adjusted to neutral pH by slowly adding 2.5 N sodium hydroxide solution to the filtrate.The precipitate was collected by filtration to give 1.23 g (44% yield) of methyl 2-aminothiazole-5-carboxylate.
References
[1] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1991, # 3, p. 349 - 352
[2] Patent: WO2003/97616, 2003, A1. Location in patent: Page/Page column 26
[3] Journal of the American Chemical Society, 1952, vol. 74, p. 5799
[4] Ann. Rep. Res. Inst. Tuberc. Kanazawa Univ., 1953, vol. 11, # 2, p. 39,41
[5] Chem.Abstr., 1955, p. 8250
Methyl 2-aminothiazole-5-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 2-aminothiazole-5-carboxylate Suppliers
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- 320-37350700
- Fax
- +32 (0)37350701
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View Lastest Price from Methyl 2-aminothiazole-5-carboxylate manufacturers
- Product
- Methyl 2-aminothiazole-5-carboxylate 6633-61-0
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-12-09
- Product
- Methyl 2-aminothiazole-5-carboxylate 6633-61-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-10
- Product
- Methyl 2-aminothiazole-5-carboxylate 6633-61-0
- Price
- US $40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-07