ChemicalBook > CAS DataBase List > 4,4'-Dimethoxytrityl chloride

4,4'-Dimethoxytrityl chloride

Product Name
4,4'-Dimethoxytrityl chloride
CAS No.
40615-36-9
Chemical Name
4,4'-Dimethoxytrityl chloride
Synonyms
DMT;DMT-CL;4,4'-(Chloro(phenyl)Methylene)bis(Methoxybenzene);4,4-DIMETHOXYTRITYL CHLORIDE;Dimethoxy Trityl Chloride;EPB49;DMT-Cl)D;DMTRT-CL;DMT CHLORIDE;TRT(MEO)2-CL
CBNumber
CB3442487
Molecular Formula
C21H19ClO2
Formula Weight
338.83
MOL File
40615-36-9.mol
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4,4'-Dimethoxytrityl chloride Property

Melting point:
123-125 °C
Boiling point:
455.07°C (rough estimate)
Density 
1.0887 (rough estimate)
vapor pressure 
0Pa at 20℃
refractive index 
1.5330 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Powder
color 
Pink
Water Solubility 
Soluble in chloroform and methanol. Partially soluble in water
Sensitive 
Moisture Sensitive
BRN 
2471942
Stability:
Hygroscopic, Moisture Sensitive
InChIKey
JBWYRBLDOOOJEU-UHFFFAOYSA-N
LogP
5.74 at 20℃
CAS DataBase Reference
40615-36-9(CAS DataBase Reference)
NIST Chemistry Reference
Methane, chlorobis(p-methoxyphenyl)phenyl-(40615-36-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-34
Safety Statements 
22-24/25-37/39-26-36-45-36/37/39
RIDADR 
3261
WGK Germany 
3
10-21
HS Code 
29093090
Toxicity
A hallucinogenic (psychedelic) agent that may catalyze the onset of emotional problems or psychosis in predisposed individuals. DMT is perhaps one of the least studied of the hallucinogens. It causes perceptual alterations and illusions, including changes in touch, taste, and odor. The thinking process is substantially altered; there are hallucinations and loss of contact with reality. There have been no overdose deaths attributed to the direct effects of DMT. The drug is very short-acting, with a duration of effect of about half an hour or less.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H335May cause respiratory irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
100013
Product name
4,4′-Dimethoxytrityl chloride
Purity
95%
Packaging
5g
Price
$61.9
Updated
2024/03/01
Sigma-Aldrich
Product number
100013
Product name
4,4′-Dimethoxytrityl chloride
Purity
95%
Packaging
25g
Price
$173
Updated
2024/03/01
TCI Chemical
Product number
D1612
Product name
4,4'-Dimethoxytrityl Chloride [Hydroxyl Protecting Agent]
Purity
>97.0%(HPLC)(T)
Packaging
5g
Price
$42
Updated
2024/03/01
TCI Chemical
Product number
D1612
Product name
4,4'-Dimethoxytrityl Chloride [Hydroxyl Protecting Agent]
Purity
>97.0%(HPLC)(T)
Packaging
25g
Price
$122
Updated
2024/03/01
Alfa Aesar
Product number
A11626
Product name
4,4'-Dimethoxytrityl chloride, 98%
Packaging
5g
Price
$46.65
Updated
2024/03/01
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4,4'-Dimethoxytrityl chloride Chemical Properties,Usage,Production

Chemical Properties

4,4'-Dimethoxytrityl chloride is pink powder

Uses

4,4'-Dimethoxytrityl chloride is a versatile protecting group for primary alcohols, specially useful in oligonucleotide synthesis

Uses

4,4'-Dimethoxytrityl chloride is used as a protective reagent for oligonucleotide synthesis. It is used for selective protection and deprotection procedures for thiol and hydroxy groups in nucleoside derivatives.

Uses

Hydroxyl protecting group for nucleosides and nucleotides.

Flammability and Explosibility

Not classified

Purification Methods

DMT crystallises from cyclohexane/acetyl chloride as the hydrochloride. Dry it over KOH pellets in a desiccator. When dissolved in *C6H6 and air is blown through, HCl is removed. It crystallises from Et2O. [Baeyer & Villiger Chem Ber 36 2788 1903, Smith et al. J Am Chem Soc 84 430 1962, Smith et al. J Am Chem Soc 85 3821 1963.] Ifit has hydrolysed considerably (see OH in IR), then repeat the crystallisation from cyclohexane/acetyl chloride — excess of AcCl is removed in a vacuum over KOH, then recrystallise it from Et2O. [Beilstein 6 IV 1042.]

4,4'-Dimethoxytrityl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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4,4'-Dimethoxytrityl chloride Suppliers

Suzhou Highfine Biotech Co., Ltd
Tel
0512-69209928 18306209922
Fax
0512-68417696
Email
cathyjia@highfine.com
Country
China
ProdList
499
Advantage
75
Nanjing Daqin Pharmaceutical Technology Co., Ltd.
Tel
025-58470199 18351831988
Fax
025-58470199
Email
sales@daqinpharma.com
Country
China
ProdList
312
Advantage
58
Shandong Kuangqi Pharmaceutical Technology Co., Ltd
Tel
13365408000
Email
535645846@qq.com
Country
China
ProdList
12
Advantage
58
Jiangsu laurel Pharma Co., Ltd
Tel
0517-83966898 15861782979
Email
32860091@qq.com
Country
China
ProdList
294
Advantage
58
Shanghai xinchenfa Chemical Technology Co.,Ltd
Tel
021-13564487020 13564487020
Email
3546809660@qq.com
Country
China
ProdList
514
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2210
Advantage
55
Wuhan EnTai Technology Development Co,.Ltd
Tel
86-27-82330560
Fax
86-27-82330547
Email
2536851935@qq.com
Country
China
ProdList
348
Advantage
69
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
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View Lastest Price from 4,4'-Dimethoxytrityl chloride manufacturers

Shanghai UCHEM Inc.
Product
4,4'-Dimethoxytrityl chloride 40615-36-9
Price
US $128.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
25kg
Release date
2023-12-19
Yunbio Tech Co.,Ltd.
Product
4,4'-Dimethoxytrityl chloride 40615-36-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2022-02-25
Hebei Mojin Biotechnology Co., Ltd
Product
4,4'-Dimethoxytrityl chloride 40615-36-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-10-17

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