ChemicalBook > CAS DataBase List > 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine
3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine
- Product Name
- 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine
- CAS No.
- 330819-85-7
- Chemical Name
- 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine
- Synonyms
- 5H-Cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine, 6,7-dihydro-2-(methylthio)-;3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine
- CBNumber
- CB34482085
- Molecular Formula
- C10H11N3S2
- Formula Weight
- 237.34
- MOL File
- 330819-85-7.mol
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3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 30mg/mL; DMF:PBS (pH 7.2) (1:4): 0.2mg/mL; DMSO: 20mg/mL; PBS (pH 7.2): insolube
- form
- A crystalline solid
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 21987
- Product name
- VU0029251
- Packaging
- 1mg
- Price
- $26
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21987
- Product name
- VU0029251
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21987
- Product name
- VU0029251
- Packaging
- 10mg
- Price
- $204
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21987
- Product name
- VU0029251
- Packaging
- 25mg
- Price
- $383
- Updated
- 2024/03/01
AK Scientific
- Product number
- 8099CD
- Product name
- 10-Methylsulfanyl-7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(12),2(6),8,10-tetraen-12-amine
- Packaging
- 5mg
- Price
- $213
- Updated
- 2021/12/16
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3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Chemical Properties,Usage,Production
Description
VU0029251 is a partial antagonist of metabotropic glutamate receptor 5 (mGluR5; Ki = 1.07 μM).1 It inhibits calcium mobilization induced by glutamate in HEK293 cell membranes expressing rat mGluR5 (IC50 = 1.7 μM).
References
1. Rodriguez, A.L., Grier, M.D., Jones, C.K., et al. Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity Mol. Pharmacol. 78(6),1105-1123(2010).
3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Suppliers
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