ChemicalBook > CAS DataBase List > 4-Fluorobenzyl bromide
4-Fluorobenzyl bromide
Chemical Properties Uses- Product Name
- 4-Fluorobenzyl bromide
- CAS No.
- 459-46-1
- Chemical Name
- 4-Fluorobenzyl bromide
- Synonyms
- 1-(BROMOMETHYL)-4-FLUOROBENZENE;Of fluoride broMide;4-Fluorobenzyl bromi;P-FLUOROBENZYL BROMIDE;4-FLUOROBENZYL BROMIDE;α-BroMo-p-fluorotoluene;α-Bromo-4-fluorotoluene;1-bromo-3-fluorotoluene;à-bromo-4-fluorotoluene;4-FLUOROBBENZYL BROMIDE
- CBNumber
- CB3471414
- Molecular Formula
- C7H6BrF
- Formula Weight
- 189.02
- MOL File
- 459-46-1.mol
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4-Fluorobenzyl bromide Property
- Boiling point:
- 85 °C15 mm Hg(lit.)
- Density
- 1.517 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.547(lit.)
- Flash point:
- >230 °F
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- soluble in Chloroform
- form
- Liquid
- Specific Gravity
- 1.517
- color
- Clear colorless to yellow
- Sensitive
- Lachrymatory
- BRN
- 636507
- InChIKey
- NVNPLEPBDPJYRZ-UHFFFAOYSA-N
- CAS DataBase Reference
- 459-46-1(CAS DataBase Reference)
- NIST Chemistry Reference
- «alpha»-Bromo-4-fluorotoluene(459-46-1)
- EPA Substance Registry System
- 4-Fluorobenzyl bromide (459-46-1)
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Safety
- Hazard Codes
- C
- Risk Statements
- 34-36
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3265 8/PG 2
- WGK Germany
- 3
- Hazard Note
- Corrosive/Lachrymatory
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29039990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
P405Store locked up.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 209538
- Product name
- 4-Fluorobenzyl bromide
- Purity
- 97%
- Packaging
- 5g
- Price
- $41.4
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 209538
- Product name
- 4-Fluorobenzyl bromide
- Purity
- 97%
- Packaging
- 25g
- Price
- $111
- Updated
- 2024/03/01
TCI Chemical
- Product number
- F0214
- Product name
- 4-Fluorobenzyl Bromide
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $32
- Updated
- 2024/03/01
TCI Chemical
- Product number
- F0214
- Product name
- 4-Fluorobenzyl Bromide
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $90
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- A10208
- Product name
- 4-Fluorobenzyl bromide, 97%
- Packaging
- 10g
- Price
- $45.65
- Updated
- 2024/03/01
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4-Fluorobenzyl bromide Chemical Properties,Usage,Production
Chemical Properties
4-Fluorobenzyl bromide (C7H6BrF, CAS registry No. 459-46-1) is a colorless to light yellow liquid. Its flash point is 74.8 oC. It is stable at room temperature in closed containers under normal storage and handling conditions. 1,3-Difluorobenzene can react with water to form toxic fumes. Therefore, it should be stored in a tightly closed container and should be stored in a cool, dry and well-ventilated area away from incompatible substances.
Uses
4-Fluorobenzyl bromide is an important intermediate in organic chemistry. 4-Fluorobenzyl bromide can be used as alkylating reagent to participate in the alkylation reaction with sulfamic esters (R-O-SO2-NH2) in liquid-liquid phase transfer conditions, resulting in the preparation of the N-dialkyled products or the corresponding ethers by scission of the O-SO2 bond, depending on the nature of R.
4-Fluorobenzyl bromide can be used for the synthesis of glycyrrhetinic acid (GA) derivatives, which are slow-binding inhibitors of tyrosinase and have inhibitory effects on melanogenesis.
Chemical Properties
Colorless to light yellow liqui
Uses
4-Fluorobenzyl bromide was used in the preparation of:
- 3-acetyl-1-(4-fluorobenzyl)-4-hydroxy-1H-indole
- 1-(4-fluorobenzyl)-5-(pyrrolidine-1-sulfonyl)isatin
- (S)-1-(4-fluorobenzyl)-5-(2-(4-fluorophenoxymethyl)pyrrolidine-1-sulfonyl)isatin
- 8-bromo 9-(4-fluorobenzyl) adenine
- 8-bromo 3-(4-fluorobenzyl) adenine
Uses
4-Fluorobenzyl Bromide is a substituted benzyl bromide reagent used in the preparation of wide range of biologically active compounds such as bronchodialators, neurochemicals and antibacterials.
4-Fluorobenzyl bromide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Fluorobenzyl bromide manufacturers
Ouhuang Engineering Materials (Hubei) Co., Ltd
- Product
- 4-Fluorobenzyl Bromide 459-46-1
- Price
- US $100.00-30.00/kg
- Min. Order
- 1kg
- Purity
- 99.93%
- Supply Ability
- 1000kg per week
- Release date
- 2024-04-25
Henan Fengda Chemical Co., Ltd
- Product
- 4-Fluorobenzyl bromide 459-46-1
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-25
Hebei Mojin Biotechnology Co., Ltd
- Product
- 4-Fluorobenzyl Bromide 459-46-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-07-27
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