4-Fluorobenzyl bromide

Chemical Properties Uses

Product Name: 4-Fluorobenzyl bromide
CAS No.: 459-46-1
Chemical Name: 4-Fluorobenzyl bromide
Synonyms: 1-(BROMOMETHYL)-4-FLUOROBENZENE;Of fluoride broMide;4-Fluorobenzyl bromi;P-FLUOROBENZYL BROMIDE;4-FLUOROBENZYL BROMIDE;α-BroMo-p-fluorotoluene;α-Bromo-4-fluorotoluene;1-bromo-3-fluorotoluene;à-bromo-4-fluorotoluene;4-FLUOROBBENZYL BROMIDE
CBNumber: CB3471414
Molecular Formula: C7H6BrF
Formula Weight: 189.02
MOL File: 459-46-1.mol

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4-Fluorobenzyl bromide Property

Boiling point:: 85 °C15 mm Hg(lit.)
Density: 1.517 g/mL at 25 °C(lit.)
refractive index: n20/D 1.547(lit.)
Flash point:: >230 °F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: soluble in Chloroform
form: Liquid
Specific Gravity: 1.517
color: Clear colorless to yellow
Sensitive: Lachrymatory
BRN: 636507
InChIKey: NVNPLEPBDPJYRZ-UHFFFAOYSA-N
CAS DataBase Reference: 459-46-1(CAS DataBase Reference)
NIST Chemistry Reference: «alpha»-Bromo-4-fluorotoluene(459-46-1)
EPA Substance Registry System: 4-Fluorobenzyl bromide (459-46-1)

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Safety

Hazard Codes: C
Risk Statements: 34-36
Safety Statements: 26-36/37/39-45
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
Hazard Note: Corrosive/Lachrymatory
TSCA: Yes
HazardClass: 8
PackingGroup: III
HS Code: 29039990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 209538
Product name: 4-Fluorobenzyl bromide
Purity: 97%
Packaging: 5g
Price: $41.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 209538
Product name: 4-Fluorobenzyl bromide
Purity: 97%
Packaging: 25g
Price: $111
Updated: 2024/03/01

TCI Chemical

Product number: F0214
Product name: 4-Fluorobenzyl Bromide
Purity: >97.0%(GC)
Packaging: 5g
Price: $32
Updated: 2024/03/01

TCI Chemical

Product number: F0214
Product name: 4-Fluorobenzyl Bromide
Purity: >97.0%(GC)
Packaging: 25g
Price: $90
Updated: 2024/03/01

Alfa Aesar

Product number: A10208
Product name: 4-Fluorobenzyl bromide, 97%
Packaging: 10g
Price: $45.65
Updated: 2024/03/01

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4-Fluorobenzyl bromide Chemical Properties,Usage,Production

Chemical Properties

4-Fluorobenzyl bromide (C7H6BrF, CAS registry No. 459-46-1) is a colorless to light yellow liquid. Its flash point is 74.8 oC. It is stable at room temperature in closed containers under normal storage and handling conditions. 1,3-Difluorobenzene can react with water to form toxic fumes. Therefore, it should be stored in a tightly closed container and should be stored in a cool, dry and well-ventilated area away from incompatible substances.

Uses

4-Fluorobenzyl bromide is an important intermediate in organic chemistry. 4-Fluorobenzyl bromide can be used as alkylating reagent to participate in the alkylation reaction with sulfamic esters (R-O-SO2-NH2) in liquid-liquid phase transfer conditions, resulting in the preparation of the N-dialkyled products or the corresponding ethers by scission of the O-SO2 bond, depending on the nature of R.
4-Fluorobenzyl bromide can be used for the synthesis of glycyrrhetinic acid (GA) derivatives, which are slow-binding inhibitors of tyrosinase and have inhibitory effects on melanogenesis.

Chemical Properties

Colorless to light yellow liqui

Uses

4-Fluorobenzyl bromide was used in the preparation of:

3-acetyl-1-(4-fluorobenzyl)-4-hydroxy-1H-indole
1-(4-fluorobenzyl)-5-(pyrrolidine-1-sulfonyl)isatin
(S)-1-(4-fluorobenzyl)-5-(2-(4-fluorophenoxymethyl)pyrrolidine-1-sulfonyl)isatin
8-bromo 9-(4-fluorobenzyl) adenine
8-bromo 3-(4-fluorobenzyl) adenine

Uses

4-Fluorobenzyl Bromide is a substituted benzyl bromide reagent used in the preparation of wide range of biologically active compounds such as bronchodialators, neurochemicals and antibacterials.

4-Fluorobenzyl bromide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Fluorobenzyl bromide Suppliers

Americas 1 Belgium 4 Canada 2 China 299 Europe 4 France 2 Germany 7 India 21 Israel 1 Italy 1 Japan 4 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 16 United States 47 Global 413

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View Lastest Price from 4-Fluorobenzyl bromide manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: 4-Fluorobenzyl Bromide 459-46-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-11

Hebei Chuanghai Biotechnology Co,.LTD

Product: 4-Fluorobenzyl bromide 459-46-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99.%
Supply Ability: 10 ton
Release date: 2024-08-22

Henan Fengda Chemical Co., Ltd

Product: 4-Fluorobenzyl bromide 459-46-1
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-25

459-46-1, 4-Fluorobenzyl bromideRelated Search:

Rocuronium bromide [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl 2,2-dimethyl-3-pro p-1-enyl-cyclopropane-1-carboxylate Diethylstilbestrol Ethyl bromodifluoroacetate Fluorobenzene Ethidium bromide 4-Fluorobenzyl chloride BRETYLIUM TOSYLATE Allyl bromide Sodium bromate alpha-Chloro-o-fluorotoluene 4-n-Propoxyphenylacetylene Bromine 1,2-Bis(bromomethyl)benzene 9-BROMOFLUORENE 2-(Trifluoromethyl)benzyl bromide 1,2,4,5-TETRAKIS(BROMOMETHYL)BENZENE Methyl bromide

P-FLUOROBENZYL BROMIDE

4-Fluoro-1-(bromomethyl)benzene

α-Bromo-4-fluorotoluene

4-Fluorobenzyl bromi

BroMobenzene of fluoride

Of fluoride broMide

1-(Bromomethyl)-4-fluorobenzene, alpha-Bromo-4-fluorotoluene

α-BroMo-p-fluorotoluene

Toluene, α-broMo-p-fluoro- (6CI,7CI,8CI)

The fluorine broMine benzyl

ALPHA-BROMO-P-FLUOROTOLUENE

ALPHA-BROMO-4-FLUOROTOLUENE

4-FLUOROBENZYL BROMIDE

1-(BROMOMETHYL)-4-FLUOROBENZENE

1-(bromomethyl)-4-fluoro-benzen

Benzene, 1-(bromomethyl)-4-fluoro-

Toluene, alpha-bromo-p-fluoro-

4-fluoro(bromomethyl)benzene

1-bromo-3-fluorotoluene

à-bromo-4-fluorotoluene

4-Fluorobenzyl bromide 90%

4-Fluorobenzyl Bromide p-Fluorobenzyl Bromide

4-FLUOROBENZYL BROMIDE 98% (GC)

4-Fluorobenzylbromide,97%

α-Bromo-4-fluorotoluene, 1-Bromomethyl-4-fluorobenzene

4-Fluorobenzyl bromide ,98%

4-FLUOROBBENZYL BROMIDE

A-BROMO-4-FLUOROTOLUENE

4-FluorobenzylBromide&gt

4-Fluorobenzyl bromide, 98%, for synthesis

4-Fluorobenzyl bromide ISO 9001：2015 REACH

α-Bromo-p-fluorotoluene

459-46-1

BENZYL HALIDE

Building Blocks

Aryl

C7

Halogenated Hydrocarbons

Organic Building Blocks

Benzyl

Fluoro-contained benzyl bromide series

alkyl bromide|alkyl Fluorine

Halogenated Heterocycles ,Pyrimidines

Fluorinated benzene series

bc0001