ChemicalBook > CAS DataBase List > 2-Methoxy-3-nitropyridine

2-Methoxy-3-nitropyridine

Product Name
2-Methoxy-3-nitropyridine
CAS No.
20265-35-4
Chemical Name
2-Methoxy-3-nitropyridine
Synonyms
2-METHOXY-3-NITROPYRIDINE;3-Nitro-2-methoxypyridine;Pyridine, 2-methoxy-3-nitro-;2-Methoxy-3-nitropyridine>METHYL 3-NITRO-2-PYRIDINYL ETHER;2-Methoxy-3-nitropyridine ISO 9001：2015 REACH
CBNumber
CB3476383
Molecular Formula
C6H6N2O3
Formula Weight
154.12
MOL File
20265-35-4.mol
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2-Methoxy-3-nitropyridine Property

Melting point:
53-55°C
Boiling point:
247.9±20.0 °C(Predicted)
Density 
1.300±0.06 g/cm3(Predicted)
Flash point:
>110℃
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
pka
-0?+-.0.10(Predicted)
color 
White to Amber
BRN 
138199
InChI
InChI=1S/C6H6N2O3/c1-11-6-5(8(9)10)3-2-4-7-6/h2-4H,1H3
InChIKey
WZNQCVOSOCGWJG-UHFFFAOYSA-N
SMILES
C1(OC)=NC=CC=C1[N+]([O-])=O
CAS DataBase Reference
20265-35-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22-41-37/38
Safety Statements 
26-36/37/39-22-36-39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M1395
Product name
2-Methoxy-3-nitropyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$104
Updated
2025/07/31
TCI Chemical
Product number
M1395
Product name
2-Methoxy-3-nitropyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$327
Updated
2025/07/31
TRC
Product number
M219128
Product name
2-Methoxy-3-nitropyridine
Packaging
2.5g
Price
$75
Updated
2021/12/16
TRC
Product number
M219128
Product name
2-Methoxy-3-nitropyridine
Packaging
500mg
Price
$60
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0021156
Product name
2-METHOXY-3-NITRO PYRIDINE
Purity
95.00%
Packaging
25G
Price
$1245.09
Updated
2021/12/16
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2-Methoxy-3-nitropyridine Chemical Properties,Usage,Production

Uses

2-Methoxy-3-nitropyridine is a pyridine compound used as a reagent in chemical reactions or as an intermediate component in organic synthesis. It can be reduced to amines and then converted to N-substituted derivatives.

Preparation

2-Methoxy-3-nitropyridine can be prepared by methylation of 2-hydroxy-3-nitropyridine[1].

Synthesis

5470-18-8

20265-35-4

Example 12 Synthesis of 2-methoxy-3-nitropyridine STR27: 2-chloro-3-nitropyridine (25 g, 0.157 mol) was suspended in methanol (300 ml), followed by addition of sodium methanolate (17 g, 0.315 mol). The reaction mixture was heated to reflux for 2 hours. After completion of the reaction, some of the solvent was removed by distillation under reduced pressure. The remaining reaction mixture was diluted with water (1 liter) and filtered to collect the precipitate precipitated. The resulting white solid was washed with copious amounts of water and subsequently dried under vacuum to afford the target product 2-methoxy-3-nitropyridine (18.2 g, 75% yield). The structure of the product was confirmed by 1H NMR (CDCl3): δ 8.42 (dd, J = 5,2 Hz, 1H); 8.28 (dd, J = 8,2 Hz, 1H); 7.06 (dd, J = 8,5 Hz, 1H); 4.13 (s, 3H).

References

[1] GRUBER W. PYRIDINE DERIVATIVES: PART VI MALONATIONS OF SUBSTITUTED NITROPYRIDINES[J]. Canadian Journal of Chemistry, 1953. DOI:10.1139/V53-152.

2-Methoxy-3-nitropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Methoxy-3-nitropyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-Methoxy-3-nitropyridine 20265-35-4
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-06-29
PNP Biotech Co. Ltd
Product
2-Methoxy-5-nitropyridine 20265-35-4
Price
US $0.00/kg
Min. Order
25kg
Purity
98%
Supply Ability
Inquiry
Release date
2022-09-16
Dideu Industries Group Limited
Product
2-Methoxy-3-nitropyridine 20265-35-4
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-07

20265-35-4, 2-Methoxy-3-nitropyridineRelated Search:

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  • 2-Methoxy-3-nitropyridine ISO 9001：2015 REACH
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  • Pyridine
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