2-Methoxy-3-nitropyridine
- Product Name
- 2-Methoxy-3-nitropyridine
- CAS No.
- 20265-35-4
- Chemical Name
- 2-Methoxy-3-nitropyridine
- Synonyms
- 2-METHOXY-3-NITROPYRIDINE;3-Nitro-2-methoxypyridine;Pyridine, 2-methoxy-3-nitro-;2-Methoxy-3-nitropyridine>METHYL 3-NITRO-2-PYRIDINYL ETHER;2-Methoxy-3-nitropyridine ISO 9001：2015 REACH
- CBNumber
- CB3476383
- Molecular Formula
- C6H6N2O3
- Formula Weight
- 154.12
- MOL File
- 20265-35-4.mol
2-Methoxy-3-nitropyridine Property
- Melting point:
- 53-55°C
- Boiling point:
- 247.9±20.0 °C(Predicted)
- Density
- 1.300±0.06 g/cm3(Predicted)
- Flash point:
- >110℃
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to crystal
- pka
- -0?+-.0.10(Predicted)
- color
- White to Amber
- BRN
- 138199
- InChI
- InChI=1S/C6H6N2O3/c1-11-6-5(8(9)10)3-2-4-7-6/h2-4H,1H3
- InChIKey
- WZNQCVOSOCGWJG-UHFFFAOYSA-N
- SMILES
- C1(OC)=NC=CC=C1[N+]([O-])=O
- CAS DataBase Reference
- 20265-35-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22-41-37/38
- Safety Statements
- 26-36/37/39-22-36-39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M1395
- Product name
- 2-Methoxy-3-nitropyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $104
- Updated
- 2025/07/31
- Product number
- M1395
- Product name
- 2-Methoxy-3-nitropyridine
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $327
- Updated
- 2025/07/31
- Product number
- M219128
- Product name
- 2-Methoxy-3-nitropyridine
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- M219128
- Product name
- 2-Methoxy-3-nitropyridine
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- CHM0021156
- Product name
- 2-METHOXY-3-NITRO PYRIDINE
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $1245.09
- Updated
- 2021/12/16
2-Methoxy-3-nitropyridine Chemical Properties,Usage,Production
Uses
2-Methoxy-3-nitropyridine is a pyridine compound used as a reagent in chemical reactions or as an intermediate component in organic synthesis. It can be reduced to amines and then converted to N-substituted derivatives.
Preparation
2-Methoxy-3-nitropyridine can be prepared by methylation of 2-hydroxy-3-nitropyridine[1].
Synthesis
5470-18-8
20265-35-4
Example 12 Synthesis of 2-methoxy-3-nitropyridine STR27: 2-chloro-3-nitropyridine (25 g, 0.157 mol) was suspended in methanol (300 ml), followed by addition of sodium methanolate (17 g, 0.315 mol). The reaction mixture was heated to reflux for 2 hours. After completion of the reaction, some of the solvent was removed by distillation under reduced pressure. The remaining reaction mixture was diluted with water (1 liter) and filtered to collect the precipitate precipitated. The resulting white solid was washed with copious amounts of water and subsequently dried under vacuum to afford the target product 2-methoxy-3-nitropyridine (18.2 g, 75% yield). The structure of the product was confirmed by 1H NMR (CDCl3): δ 8.42 (dd, J = 5,2 Hz, 1H); 8.28 (dd, J = 8,2 Hz, 1H); 7.06 (dd, J = 8,5 Hz, 1H); 4.13 (s, 3H).
References
[1] GRUBER W. PYRIDINE DERIVATIVES: PART VI MALONATIONS OF SUBSTITUTED NITROPYRIDINES[J]. Canadian Journal of Chemistry, 1953. DOI:10.1139/V53-152.
2-Methoxy-3-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Methoxy-3-nitropyridine Suppliers
- Tel
- --
- Fax
- --
- szeviki@szeviki.hu
- Country
- Hungary
- ProdList
- 23
- Advantage
- 58
View Lastest Price from 2-Methoxy-3-nitropyridine manufacturers
- Product
- 2-Methoxy-3-nitropyridine 20265-35-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-06-29
- Product
- 2-Methoxy-5-nitropyridine 20265-35-4
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 98%
- Supply Ability
- Inquiry
- Release date
- 2022-09-16
- Product
- 2-Methoxy-3-nitropyridine 20265-35-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-07