ChemicalBook > CAS DataBase List > Fluorene

Fluorene

Product Name
Fluorene
CAS No.
86-73-7
Chemical Name
Fluorene
Synonyms
9H-FLUORENE;FLUOCINONIDE;Fluorene 98%;DIPHENYLENEMETHANE;uorene;FLUORENE;NSC 6787;Fluorene>Fluorene,98%;2,3-BENZINDENE
CBNumber
CB3717011
Molecular Formula
C13H10
Formula Weight
166.22
MOL File
86-73-7.mol
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Fluorene Property

Melting point:
111-114 °C (lit.)
Boiling point:
298 °C (lit.)
Density 
1.2
vapor pressure 
13 hPa (146 °C)
refractive index 
1.6470
Flash point:
151 °C
storage temp. 
room temp
solubility 
0.002g/l insoluble
form 
Crystalline Powder
pka
>15 (Christensen et al., 1975)
color 
Almost white to light brown
Water Solubility 
insoluble
Merck 
14,4155
BRN 
1363491
Henry's Law Constant
1.89(x 10-5 atm?m3/mol) at 4 °C, 12.5 at 25 °C (dynamic equilibrium method, Bamford et al., 1999)
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey
NIHNNTQXNPWCJQ-UHFFFAOYSA-N
LogP
4.164
CAS DataBase Reference
86-73-7(CAS DataBase Reference)
NIST Chemistry Reference
Fluorene(86-73-7)
IARC
3 (Vol. Sup 7, 92) 2010
EPA Substance Registry System
Fluorene (86-73-7)
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Safety

Hazard Codes 
N,T,F,Xn,Xi
Risk Statements 
50/53-39/23/24/25-23/24/25-11-67-65-38-36/38-36/37/38-52/53-20
Safety Statements 
60-61-24/25-45-36/37-16-7-62-33-24-22-36/37/39-27-26-25-9
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
RTECS 
LL5670000
Hazard Note 
Harmful
TSCA 
Yes
HazardClass 
9
PackingGroup 
III
HS Code 
29029080
Hazardous Substances Data
86-73-7(Hazardous Substances Data)
Toxicity
Drinking water standard: No MCLGs or MCLs have been proposed, however, a DWEL of 1 mg/L was recommended (U.S. EPA, 2000).
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
128333
Product name
Fluorene
Purity
98%
Packaging
5g
Price
$41.8
Updated
2024/03/01
Sigma-Aldrich
Product number
48568
Product name
Fluorene
Purity
analytical standard
Packaging
5000mg
Price
$74.9
Updated
2024/03/01
Sigma-Aldrich
Product number
128333
Product name
Fluorene
Purity
98%
Packaging
100g
Price
$92.7
Updated
2024/03/01
Sigma-Aldrich
Product number
8.20572
Product name
Fluorene
Purity
for synthesis
Packaging
100g
Price
$97
Updated
2022/05/15
Sigma-Aldrich
Product number
8.20572
Product name
Fluorene
Purity
for synthesis
Packaging
820572
Price
$1877
Updated
2022/05/15
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Fluorene Chemical Properties,Usage,Production

Description

Fluorene, when pure, is found as dazzlingwhite flakes or small, crystalline plates. It is fluorescentwhen impure. Polynuclear aromatic hydrocarbons (PAHs)are compounds containing multiple benzene rings and arealso called polycyclic aromatic hydrocarbons. Molecularweight=166.23; Boiling point=293C (decomposes);Freezing/Melting point=116-117C; Flash point=151C. Hazard Identification (based on NFPA-704 MRating System): Health 1, Flammability 1, Reactivity 0.Insoluble in water.

Chemical Properties

white crystals

Chemical Properties

Fluorene, when pure, is found as dazzling white flakes or small, crystalline plates. It is fluorescent when impure. Polycyclic aromatic hydrocarbons (PAHs) are compounds containing multiple benzene rings and are also called polynuclear aromatic hydrocarbons.

Physical properties

Small white leaflets or crystalline flakes from ethanol. Fluorescent when impure.

Uses

Fluorene was used study the extraction of specific, semiconducting single-wall carbon nanotubes (SWCNTs).

Uses

Polycyclic aromatic hydrocarbons as micropollutants.

Definition

ChEBI: An ortho-fused tricyclic hydrocarbon that is a major component of fossil fuels and their derivatives

Synthesis Reference(s)

Journal of the American Chemical Society, 73, p. 2656, 1951 DOI: 10.1021/ja01150a069
Synthetic Communications, 26, p. 1467, 1996 DOI: 10.1080/00397919608003512
The Journal of Organic Chemistry, 37, p. 1273, 1972 DOI: 10.1021/jo00973a049

General Description

White leaflets. Sublimes easily under a vacuum. Fluorescent when impure.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic hydrocarbons, such as Fluorene, and strong oxidizing agents. They can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), nitration, sulfonation, and the Friedel-Crafts reaction.

Hazard

Questionable carcinogen.

Health Hazard

Acute toxicity in animals is very low. AnLD50 (intraperitoneal) in mice is 2000 mg/kg.Carcinogenicity of this compound in animalsis not well established. It tested negative in ahistidine reversion–Ames test.

Health Hazard

ACUTE/CHRONIC HAZARDS: Fire hazards: Slight, when exposed to heat or flame.

Potential Exposure

Fluorene is used in resins, dyes, and is a chemical intermediate.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.

Source

Fluorene was detected in groundwater beneath a former coal gasification plant in Seattle, WA at a concentration of 140 μg/L (ASTR, 1995). Present in diesel fuel and corresponding aqueous phase (distilled water) at concentrations of 350 to 900 mg/L and 12 to 26 g/L, respectively (Lee et al., 1992). Schauer et al. (1999) reported fluorene in diesel fuel at a concentration of 52 g/g and in a diesel-powered medium-duty truck exhaust at an emission rate of 34.6 g/km. Diesel fuel obtained from a service station in Schlieren, Switzerland contained fluorene at an estimated concentration of 170 mg/L (Schluep et al., 2001).
Based on laboratory analysis of 7 coal tar samples, fluorene concentrations ranged from 1,100 to 12,000 ppm (EPRI, 1990). Lao et al. (1975) reported a fluorene concentration of 27.39 g/kg in a coal tar sample. Detected in 1-yr aged coal tar film and bulk coal tar at an identical concentration of 4,400 mg/kg (Nelson et al., 1996). A high-temperature coal tar contained fluorene at an average concentration of 0.64 wt % (McNeil, 1983). Identified in high-temperature coal tar pitches at concentrations ranging from 800 to 4,000 mg/kg (Arrendale and Rogers, 1981). Lee et al. (1992a) equilibrated 8 coal tars with distilled water at 25 °C. The maximum concentration of fluorene observed in the aqueous phase was 0.3 mg/L.
Fluorene was detected in asphalt fumes at an average concentration of 34.95 ng/m3 (Wang et al., 2001).
Nine commercially available creosote samples contained fluorene at concentrations ranging from 19,000 to 73,000 mg/kg (Kohler et al., 2000).
Thomas and Delfino (1991) equilibrated contaminant-free groundwater collected from Gainesville, FL with individual fractions of three individual petroleum products at 24–25 °C for 24 h. The aqueous phase was analyzed for organic compounds via U.S. EPA approved test method 625. Average fluorene concentrations reported in water-soluble fractions of unleaded gasoline, kerosene, and diesel fuel were 1, 3, and 10 μg/L, respectively.
Fluorene was detected in soot generated from underventilated combustion of natural gas doped with toluene (3 mole %) (Tolocka and Miller, 1995).
Schauer et al. (2001) measured organic compound emission rates for volatile organic compounds, gas-phase semi-volatile organic compounds, and particle-phase organic compounds from the residential (fireplace) combustion of pine, oak, and eucalyptus. The gas-phase emission rates of fluorene were 4.44 mg/kg of pine burned, 3.83 mg/kg of oak burned, and 2.613 mg/kg of eucalyptus burned.
California Phase II reformulated gasoline contained fluorene at a concentration of 4.35 mg/kg. Gas-phase tailpipe emission rates from gasoline-powered automobiles with and without catalytic converters were 9.72 and 358 μg/km, respectively (Schauer et al., 2002).
Under atmospheric conditions, a low rank coal (0.5–1 mm particle size) from Spain was burned in a fluidized bed reactor at seven different temperatures (50 °C increments), beginning at 650 °C. The combustion experiment was also conducted at different amounts of excess oxygen (5 to 40%) and different flow rates (700 to 1,100 L/h). At 20% excess oxygen and a flow rate of 860 L/h, the amount of fluorine emitted ranged from 850.7 ng/kg at 950 °C to 3,632.8 ng/kg at 750 °C. The greatest amount of PAHs emitted were observed at 750 °C (Mastral et al., 1999).
In one study, fluorene comprised about 7.6% of polyaromatic hydrocarbons in creosote (Grifoll et al., 1995).
Identified as an impurity in commcerially available acenaphthene (Marciniak, 2002).
Typical concentration of fluorene in a heavy pyrolysis oil is 1.6 wt % (Chevron Phillips, May 2003).

Environmental Fate

Biological. Fluorene was statically incubated in the dark at 25 °C with yeast extract and settled domestic wastewater inoculum. Significant biodegradation with gradual adaptation was observed. At concentrations of 5 and 10 mg/L, biodegradation yields at the end of 4 wk of incubation were 77 and 45%, respectively (Tabak et al., 1981).
Photolytic. Fluorene reacts with photochemically produced OH radicals in the atmosphere. The atmospheric half-life was estimated to range from 6.81 to 68.1 h (Atkinson, 1987). Behymer and Hites (1985) determined the effect of different substrates on the rate of photooxidation of fluorene (25 μg/g substrate) using a rotary photoreactor. The photolytic half-lives of fluorene using silica gel, alumina, and fly ash were 110, 62, and 37 h, respectively. Gas-phase reaction rate constants for OH radicals, NO3 radicals, and ozone at 24 °C were 1.6 x 10-11, 3.5 x 10-15, and <2 x 10-19 in cm3/molecule?sec, respectively (Kwok et al., 1997).
Chemical/Physical. Oxidation by ozone to fluorenone has been reported (Nikolaou, 1984). Chlorination of fluorene in polluted humus poor lake water gave a chlorinated derivative tentatively identified as 2-chlorofluorene (Johnsen et al., 1989). This compound was also identified as a chlorination product of fluorene at low pH (<4) (Oyler et al., 1983). It was suggested that the chlorination of fluorene in tap water accounted for the presence of chlorofluorene (Shiraishi et al., 1985).

storage

Color Code—Green: General storage may be used.Prior to working with this chemical you should be trainedon its proper handling and storage. Store in tightly closedcontainers in a cool, well-ventilated area away from oxidizers and source of ignition.

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz ardous material, Technical Name Required.

Purification Methods

Purify fluorene by chromatography of CCl4 or pet ether (b 40-60o) solution on alumina, with *benzene as eluent. Crystallise it from 95% EtOH, 90% acetic acid and again from EtOH. Crystallisation using glacial acetic acid retains an impurity which is removed by partial mercuration and precipitation with LiBr [Brown et al. J Am Chem Soc 84 1229 1962]. It has also been crystallised from hexane, or *benzene/EtOH, distilled under vacuum and purified by zone refining. [Gorman et al. J Am Chem Soc 107 4404 1985, Beilstein 5 IV 2142.]

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explo sions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Compound can react exo thermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), nitration, sulfonation, and the Friedel Crafts reaction.

Waste Disposal

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately when there is a release of this designated hazardous substance, in an amount equal to or greater than its RQ listed above. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metro politan area call (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (Section IV. D.3.b).

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View Lastest Price from Fluorene manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Fluorene 86-73-7
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-07
Hebei Weibang Biotechnology Co., Ltd
Product
Fluorene 86-73-7
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-21
Shaanxi Dideu Medichem Co. Ltd
Product
Fluorene 86-73-7
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
99%
Supply Ability
2000tons
Release date
2019-12-31

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  • FLUORENE, 1X1ML, MEOH, 200UG/ML
  • Fluorene,98%
  • fluorene solution
  • 9H-Fluorene 98%
  • Fluorene Zone Refined
  • Fluorene, 98% 100GR
  • Fluorene, 98% 25GR
  • Fluorene, 98% 500GR
  • NSC 6787
  • Fluorene Standard
  • uorene
  • FluoreneSolution,1000mg/L,1ml
  • FluoreneSolution,500mg/L,1ml
  • FluoreneSolution,100mg/L,1ml
  • FluoreneZoneRefined(numberofpasses:70)&gt
  • FluoreneSolution,2000mg/L,1ml
  • FluoreneSolution,50mg/L,1ml
  • Fluorene 200 μg/mL In Isooctane
  • Fluorene&gt
  • Fluorene (8CI)
  • Fluorene in Methanol
  • Fluorene 10 μg/ml Cyclohexane
  • Fluorene 100 μg/ml Acetonitrile
  • Fluorene 100 μg/ml Cyclohexane
  • L20800000ALFluorenE10μg/mLin Acetonitrile
  • L20800000CY FluorenE10μg/mLin Cyclohexane
  • XA20800000ALFluorenE100μg/mLin Acetonitrile
  • 86-73-7
  • 86737