2-Bromo-5-nitrobenzotrifluoride
- Product Name
- 2-Bromo-5-nitrobenzotrifluoride
- CAS No.
- 367-67-9
- Chemical Name
- 2-Bromo-5-nitrobenzotrifluoride
- Synonyms
- 2-Bromo-5-nitrobenzo;Alvocidib Impurity 32;LABOTEST-BB LT01143236;Bicalutamide Impurity 5;Bicalutamide Impurity 3;Bicalutamide Impurity 10;Bicalutamide Impurity 20;2-Bromo-5-nitrobenzotrifluorid;2-broMo-5-nitrotrifluorotoluol;2-Bromo-5-nitrobenzotrifluride
- CBNumber
- CB3721603
- Molecular Formula
- C7H3BrF3NO2
- Formula Weight
- 270
- MOL File
- 367-67-9.mol
2-Bromo-5-nitrobenzotrifluoride Property
- Melting point:
- 41-44 °C (lit.)
- Boiling point:
- 87-88 °C/3 mmHg (lit.)
- Density
- 1.7750 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- color
- White to Light yellow to Green
- BRN
- 2460260
- Exposure limits
- ACGIH: TWA 2.5 mg/m3
NIOSH: IDLH 250 mg/m3 - InChI
- InChI=1S/C7H3BrF3NO2/c8-6-2-1-4(12(13)14)3-5(6)7(9,10)11/h1-3H
- InChIKey
- SXEQQBBOAMHOID-UHFFFAOYSA-N
- SMILES
- C1(Br)=CC=C([N+]([O-])=O)C=C1C(F)(F)F
- CAS DataBase Reference
- 367-67-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 37/39-26-24/25
- RIDADR
- 2306
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29049090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 365769
- Product name
- 2-Bromo-5-nitrobenzotrifluoride
- Purity
- 97%
- Packaging
- 5g
- Price
- $31.2
- Updated
- 2023/06/20
- Product number
- B3686
- Product name
- 2-Bromo-5-nitrobenzotrifluoride
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $24
- Updated
- 2025/07/31
- Product number
- B3686
- Product name
- 2-Bromo-5-nitrobenzotrifluoride
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $95
- Updated
- 2025/07/31
- Product number
- B697970
- Product name
- 2-Bromo-5-nitrobenzotrifluoride
- Packaging
- 5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 264248
- Product name
- 2-Bromo-5-nitrobenzotrifluoride
- Packaging
- 100g
- Price
- $380
- Updated
- 2021/12/16
2-Bromo-5-nitrobenzotrifluoride Chemical Properties,Usage,Production
Chemical Properties
yellow crystals
Uses
2-Bromo-5-nitrobenzotrifluoride may be used in the preparation of:
- new unsymmetrical diamine monomer containing both the benzimidazole ring and trifluoromethyl group, 6,4′-diamino-2′-trifluoromethyl-2-phenylbenzimidazole
- 2,5-bis[(4-nitro-2-trifluoromethylphenoxy)-phenyl]diphenylphosphine oxide (BNTFDPO)
Synthesis
392-83-6
367-67-9
General procedure for the synthesis of 2-bromo-5-nitrobenzotrifluoride from o-bromobenzotrifluoride: 260 g of concentrated sulfuric acid (98%) was placed in a reaction flask at room temperature, and 120 g of fuming nitric acid was added slowly to prepare a nitrification acid mixture. The temperature of the reaction system was maintained at 50-60°C, and 390g of o-bromobenzotrifluoride was slowly added to the mixed acid. After the addition was completed, the temperature was maintained and the reaction continued to be stirred until the GC test showed that the raw material was completely consumed and the reaction was completed. After the reaction solution was left to stratify, the upper organic phase was separated and washed to neutrality with alkali. A bright yellow liquid was obtained, which was immediately post-treated to finally obtain 450.4 g of 2-bromo-5-nitrobenzotrifluoride, with a GC purity of 95% and a yield of 92%.
References
[1] Patent: CN106905104, 2017, A. Location in patent: Paragraph 0020-0021
[2] Journal of the American Chemical Society, 1951, vol. 73, p. 3932
2-Bromo-5-nitrobenzotrifluoride Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromo-5-nitrobenzotrifluoride Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from 2-Bromo-5-nitrobenzotrifluoride manufacturers
- Product
- 2-Bromo-5-nitrobenzotrifluoride 367-67-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-07-01
- Product
- 2-Bromo-5-nitrobenzotrifluoride 367-67-9
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-05
- Product
- 2-Bromo-5-nitrobenzotrifluoride 367-67-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 50mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-08