Ginsenoside Rh2
- Product Name
- Ginsenoside Rh2
- CAS No.
- 78214-33-2
- Chemical Name
- Ginsenoside Rh2
- Synonyms
- 20(S)-Rh2;GINSENOSIDE RH2;Ginsenoside Rh2-RM;Ginsenoside Rh2(P);GINSENOSIDE Rh2(SH);Ginsenoside Rh2(AS);Ginsenoside Rh2 ,98%;3β-(β-D-Glucopyranosyl;R-form-Ginsenoside Rh2;Ginsenoside Rh2, 20(S)-
- CBNumber
- CB3728899
- Molecular Formula
- C36H62O8
- Formula Weight
- 622.88
- MOL File
- 78214-33-2.mol
Ginsenoside Rh2 Property
- Melting point:
- 139-144 °C
- Boiling point:
- 726.4±60.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
- pka
- 12.91±0.70(Predicted)
- form
- Solid
- color
- White
- InChIKey
- CKUVNOCSBYYHIS-IRFFNABBSA-N
- LogP
- 5.620 (est)
- CAS DataBase Reference
- 78214-33-2(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 73658
- Product name
- Ginsenoside Rh2
- Purity
- analytical standard
- Packaging
- 10mg
- Price
- $714
- Updated
- 2024/03/01
- Product number
- 23390
- Product name
- Ginsenoside Rh2
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $49
- Updated
- 2024/03/01
- Product number
- 23390
- Product name
- Ginsenoside Rh2
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $190
- Updated
- 2024/03/01
- Product number
- 23390
- Product name
- Ginsenoside Rh2
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $286
- Updated
- 2024/03/01
- Product number
- 23390
- Product name
- Ginsenoside Rh2
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $651
- Updated
- 2024/03/01
Ginsenoside Rh2 Chemical Properties,Usage,Production
Description
Ginsenoside Rh2 is a steroid glycoside found in plants of the genus Panax that has diverse biological activities. It inhibits release of β-hexosaminidase from RBL-2H3 cells (IC50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a dose of 25 mg/kg. It inhibits growth of HRA ovarian and BxPC-3 pancreatic cancer cells in a dose-dependent manner. In vivo, ginsenoside Rh2 decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma. Ginsenoside Rh2 also reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury.
Chemical Properties
White solid
Uses
20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro.
Definition
ChEBI: A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.
Biological Activity
Ginsenoside-Rh2, a plant glycosidewith a dammarane skeleton, has been shown to induce apoptosis in a caspase 3,8-dependent manner or the activation of cyclinA-Cdk2 by caspase 3-mediated cleavage of p21(WAF1/CIP1). Also, ginsenoside-Rh2 was shown to inhibit proliferation by inducing the protein expression of p21 and reducing the protein levels of cyclin D, which resulted in the downregulation of cyclin/Cdk complex kinase activity, a reduction in phosphorylation of pRb and the inhibition of E2F release or modulation of MAP kinases in various cancer cells[1].
Ginsenoside Rh2 Preparation Products And Raw materials
Raw materials
Preparation Products
Ginsenoside Rh2 Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6581
- Advantage
- 61
- Tel
- --
- Fax
- --
- enquiry@leancare.co.uk
- Country
- United Kingdom
- ProdList
- 6446
- Advantage
- 42
- Tel
- --
- Fax
- --
- sales@etascientific.com
- Country
- United Kingdom
- ProdList
- 6090
- Advantage
- 34
- Tel
- --
- Fax
- --
- sales@seqchem.com
- Country
- United Kingdom
- ProdList
- 3113
- Advantage
- 69
- Tel
- --
- Fax
- --
- info@apinchemicals.com
- Country
- United Kingdom
- ProdList
- 6807
- Advantage
- 42
View Lastest Price from Ginsenoside Rh2 manufacturers
- Product
- Ginsenoside Rh2 78214-33-2
- Price
- US $100.00-1000.00/KG
- Min. Order
- 1KG
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-10-06
- Product
- Ginsenoside Rh2 78214-33-2
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-09-27
- Product
- Ginsenoside Rh2 78214-33-2
- Price
- US $80.00/g
- Min. Order
- 1mg
- Purity
- 95%
- Supply Ability
- 50kg
- Release date
- 2020-03-04