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OMEGA-GRAMMOTOXIN SIA

Product Name
OMEGA-GRAMMOTOXIN SIA
CAS No.
152617-90-8
Chemical Name
OMEGA-GRAMMOTOXIN SIA
Synonyms
GRTX;ω-Grammotoxin SIA;w-Grammotoxin SIA;ω-Grammotoxin SIA;OMEGA-GRAMMOTOXIN SIA;ASP-CYS-VAL-ARG-PHE-TRP-GLY-LYS-CYS-SER-GLN-THR-SER-ASP-CYS-CYS-PRO-HIS-LEU-ALA-CYS-LYS-SER-LYS-TRP-PRO-ARG-ASN-ILE-CYS-VAL-TRP-ASP-GLY-SER-VAL
CBNumber
CB3749418
Molecular Formula
C177H268N52O50S6
Formula Weight
4116.73
MOL File
Mol file
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OMEGA-GRAMMOTOXIN SIA Property

storage temp. 
−20°C
solubility 
aqueous buffer: soluble
Sequence
Asp-Cys-Val-Arg-Phe-Trp-Gly-Lys-Cys-Ser-Gln-Thr-Ser-Asp-Cys-Cys-Pro-His-Leu-Ala-Cys-Lys-Ser-Lys-Trp-Pro-Arg-Asn-Ile-Cys-Val-Trp-Asp-Gly-Ser-Val-NH2 (Disulfide bridge:Cys2-Cys16;Cys9-Cys21;Cys15-Cys30)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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OMEGA-GRAMMOTOXIN SIA Chemical Properties,Usage,Production

Uses

ω-Grammotoxin SIA (GrTx) is P/Q and N-type voltage-gated Calcium channels inhibitor. ω-Grammotoxin SIA is also a protein toxin that can be obtained from spider venom. ω-Grammotoxin SIA has the potential to study neurological diseases as well as cardiovascular diseases[1].

References

[1] Takeuchi K, et al. Solution structure of omega-grammotoxin SIA, a gating modifier of P/Q and N-type Ca(2+) channel. J Mol Biol. 2002 Aug 16;321(3):517-26. DOI:10.1016/s0022-2836(02)00595-8

OMEGA-GRAMMOTOXIN SIA Preparation Products And Raw materials

Raw materials

Preparation Products

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OMEGA-GRAMMOTOXIN SIA Suppliers

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152617-90-8, OMEGA-GRAMMOTOXIN SIARelated Search:

TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) TERT-BUTYL ISOCYANIDE Cupric acetylacetonate SALCOMINE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Ethyl isocyanoacetate Benzyl isocyanide METHYL ISOCYANOACETATE Aluminum acetylacetonate PHENYLSELENOL 2,4-PENTANEDIONE, SILVER DERIVATIVE Ferric acetylacetonate Tris(2,4-pentanedionato)chroMiuM(III) N-BUTYLISOCYANIDE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Tosylmethyl isocyanide COBALT(II) ACETYLACETONATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)

  • ASP-CYS-VAL-ARG-PHE-TRP-GLY-LYS-CYS-SER-GLN-THR-SER-ASP-CYS-CYS-PRO-HIS-LEU-ALA-CYS-LYS-SER-LYS-TRP-PRO-ARG-ASN-ILE-CYS-VAL-TRP-ASP-GLY-SER-VAL
  • GRTX
  • OMEGA-GRAMMOTOXIN SIA
  • ω-Grammotoxin SIA
  • w-Grammotoxin SIA
  • ω-Grammotoxin SIA
  • 152617-90-8
  • C177H268N52O50S6
  • Calcium Channel Modulators
  • Peptide Toxins
  • Voltage-gated Ion Channels