ChemicalBook > CAS DataBase List > 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE

1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE

Product Name: 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE
CAS No.: 154471-65-5
Chemical Name: 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE
Synonyms: 1-methyl-3-trifluoromethylpyrazol;1-Methyl-3-(trifluoroMethyl)pyrazole;1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE;1H-Pyrazole, 1-methyl-3-(trifluoromethyl)-;1-Methyl-3-trifluoromethyl-1H-pyrazole ,97%
CBNumber: CB3759512
Molecular Formula: C5H5F3N2
Formula Weight: 150.1
MOL File: 154471-65-5.mol

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1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE Property

Boiling point:: 137.7±35.0 °C(Predicted)
Density: 1.32g/ml
storage temp.: 2-8°C
pka: -0.71±0.10(Predicted)
Appearance: Colorless to light yellow Liquid
InChI: InChI=1S/C5H5F3N2/c1-10-3-2-4(9-10)5(6,7)8/h2-3H,1H3
InChIKey: MQSLINQSJFALSP-UHFFFAOYSA-N
SMILES: N1(C)C=CC(C(F)(F)F)=N1

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Safety

Safety Statements: 22-24/25
HS Code: 29331990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: M332173
Product name: 1-Methyl-3-(trifluoromethyl)-1H-pyrazole
Packaging: 500mg
Price: $65
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0016506
Product name: 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE
Purity: 95.00%
Packaging: 250MG
Price: $146.06
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK135649
Product name: 1-Methyl-3-trifluoromethyl-1H-pyrazole
Purity: 97%
Packaging: 1g
Price: $149
Updated: 2021/12/16

Apolloscientific

Product number: PC31708
Product name: 1-Methyl-3-(trifluoromethyl)-1H-pyrazole
Packaging: 1g
Price: $151
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-3-U9
Product name: 1-Methyl-3-(trifluoromethyl)-1H-pyrazole
Packaging: 1g
Price: $167
Updated: 2021/12/16

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1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Synthesis

59938-06-6

60-34-4

153085-15-5

154471-65-5

(E)-1-ethoxy-3-trifluoromethyl-1,3-butadiene (ETFBO, 270 g, 1.61 mol, 1.00 eq.) was dissolved in methanol (750 mL). The resulting solution was cooled in an ice-water bath, followed by the slow dropwise addition of methylhydrazine (88.3 mL, 77.7 g, 1.69 mol, 1.05 eq.) over 20 min. The reaction mixture was heated to 55 °C and stirred in dry air (via a drying tube) at this temperature for 20 hours. Upon completion of the reaction, the solvent was removed by rotary evaporation and the residue was subjected to decompression distillation: the first fraction was collected at 150 mbar, bath temperature of 130 °C, and collection temperature of 73-85 °C to give 129 g of the mixture of isomers, and the second fraction was collected at 70 mbar, bath temperature of 150 °C, and collection temperature of 75-85 °C to give 24 g of 1 -methyl-3-trifluoromethyl-1H-pyrazole. the total yield was 153 g (1.02 mol), 63% yield.

References

[1] Patent: EP2662359, 2013, A1. Location in patent: Page/Page column 6; 10

1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE Preparation Products And Raw materials

Raw materials

n-Butyl vinyl ether Ethyl vinyl ether Trifluoroacetic acid Trifluoroacetic anhydride Diethyl ether Dichloromethane Methylhydrazine Methanol Pyridine 4-Dimethylaminopyridine

Preparation Products

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1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE Suppliers

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View Lastest Price from 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE manufacturers

Career Henan Chemical Co

Product: 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE 154471-65-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-02

154471-65-5, 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLERelated Search:

2-[1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-5-YL]-THIOPHENE-5-CARBOXALDEHYDE 5-HYDROXY-1-METHYL-3-TRIFLUOROMETHYL-1H-PYRAZOLE 2-[1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-5-YL]-THIOPHENE-5-CARBOXYLIC ACID 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXALDEHYDE 3-Hydroxy-1-methyl-5-trifluoromethyl-1H-pyrazole, 99+%,5-HYDROXY-2-METHYL-3-TRIFLUOROMETHYL-1H-PYRAZOLE (3-(Trifluoromethyl)-1-methyl-1H-pyrazol-4-yl)methanamine hydrochloride ,97% (5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANAMINE 3-(Trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide ,98% Penthiopyrad 1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 2-METHYL-5-TRIFLUOROMETHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID 2-[1-METHYL-5-(TRIFLUOROMETHYL)PYRAZOL-3-YL]-THIOPHENE-5-SULFONYL CHLORIDE 5-[1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-5-YL]THIOPHENE2-SULFONYL CHLORIDE 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-SULFONYL CHLORIDE 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 3-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE 3-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-AMINE ETHYL 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE

1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE

1-Methyl-3-trifluoromethyl-1H-pyrazole ,97%

1-Methyl-3-(trifluoroMethyl)pyrazole

1H-Pyrazole, 1-methyl-3-(trifluoromethyl)-

1-methyl-3-trifluoromethylpyrazol

154471-65-5

C5H5F3N2

C5H5F3N